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Motor and Perceptual Timing in Parkinson’s Disease

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Book cover Neurobiology of Interval Timing

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 829))

Abstract

Neuroimaging has been a powerful tool for understanding the neural architecture of interval timing. However, identifying the critical brain regions engaged in timing was initially driven by investigation of human patients and animals. This chapter draws on the important contribution that the study of patients with Parkinson’s disease (PD) has made in identifying the basal ganglia as a key component of motor and perceptual timing. The chapter initially describes the experimental tasks that have been critical in PD (and non-PD) timing research before systematically discussing the results from behavioural studies. This is followed by a critique of neuroimaging studies that have given insight into the pattern of neural activity during motor and perceptual timing in PD. Finally, discussion of the effects of medical and surgical treatment on timing in PD enables further evaluation of the role of dopamine in interval timing.

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Author information

Authors and Affiliations

  1. School of Psychology, Cardiff University, Cardiff, UK

    Catherine R. G. Jones

  2. Sobell Department of Motor Neuroscience and Movement Disorders, UCL Institute of Neurology, London, UK

    Marjan Jahanshahi

Authors
  1. Catherine R. G. Jones
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  2. Marjan Jahanshahi
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Correspondence to Catherine R. G. Jones .

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Editors and Affiliations

  1. Campus Juriquilla, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Queretaro, Querétaro, Mexico

    Hugo Merchant

  2. Campus Juriquilla, Instituto de Neurobiología, Universidad Nacional Autónoma de México, Queretaro, Querétaro, Mexico

    Victor de Lafuente

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Jones, C.R.G., Jahanshahi, M. (2014). Motor and Perceptual Timing in Parkinson’s Disease. In: Merchant, H., de Lafuente, V. (eds) Neurobiology of Interval Timing. Advances in Experimental Medicine and Biology, vol 829. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1782-2_14

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