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Allergic Inflammation and Atopic Disease: Role of Th9 Cells

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Th9 Cells

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1585))

Abstract

IL-9-producing T helper cells (Th9) have recently emerged as an important T cell subset contributing to the pathogenicity of allergic diseases. Here, we describe the role of Th9 cells in allergic inflammation and provide detailed protocols to characterize IL-9-producing T cells and analyze OVA-specific IL-9 production in allergic lung diseases using a mouse model of OVA-induced chronic allergic lung inflammation.

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Acknowledgment

We gratefully thank all members of the Angkasekwinai lab and the Chen Dong lab at the University of Texas MD Anderson Cancer Center for optimization of this protocol and for lab training.

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Authors and Affiliations

  1. Department of Medical Technology, Faculty of Allied Health Sciences, Thammasat University, Pathumthani, 12120, Thailand

    Pornpimon Angkasekwinai

  2. Graduate Program, Faculty of Allied Health Sciences, Thammasat University, Pathumthani, 12120, Thailand

    Pornpimon Angkasekwinai

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  1. Pornpimon Angkasekwinai
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Correspondence to Pornpimon Angkasekwinai .

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Editors and Affiliations

  1. School of Bio Science, Sir JC Bose Laboratory Complex, Indian Institute of Technology, Kharagpur, West Bengal, India

    Ritobrata Goswami

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Angkasekwinai, P. (2017). Allergic Inflammation and Atopic Disease: Role of Th9 Cells. In: Goswami, R. (eds) Th9 Cells. Methods in Molecular Biology, vol 1585. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6877-0_15

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  • DOI: https://doi.org/10.1007/978-1-4939-6877-0_15

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-6876-3

  • Online ISBN: 978-1-4939-6877-0

  • eBook Packages: Springer Protocols

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