Skip to main content

Cyclodestructive Procedures

  • Chapter

Abstract

■ The main advantages of transscleral cyclodestructive procedures compared to other glaucoma surgical procedures are (a) ease of performance and (b) possibility of retreatments.

■ Both transscleral cyclocryocoagulation and cyclophotocoagulation using either Nd:YAG or diode laser are characterized by (a) a comparable success rate and (b) no linear dosage–efficacy relationship.

■ Because transscleral cyclophotocoagulation acts more selectively (by melanin absorption) than cyclocryocoagulation, (a) postoperative inflammatory reaction is less intense and (b) the risk of further scleral damage, such as scleral atrophy from scleritis, is lower.

■ There is a strong age-dependent probability of success for all cyclodestructive procedures, which is independent of the underlying type of glaucoma.

■ Transscleral cyclophotocoagulation has not only a lower risk profile, but also a lower success rate than other surgical procedures in pediatric glaucoma, including secondary glaucoma in pediatric uveitis. It remains a surgical procedure of last choice in children.

■ Transscleral cyclophotocoagulation offers a good therapeutic opportunity in older patients with uveitic glaucoma after other glaucoma surgery has failed. Probably it has the best benefit–risk ratio in scleritis-associated glaucoma if parameters of application are reduced.

■ Endoscopic cyclophotocoagulation is an intraocular procedure, which allows more precise diode laser application under direct visualization of the ciliary processes. Whereas the results in refractory glaucoma are encouraging, success rate is much lower in pediatric glaucoma. More experience is needed with this treatment modality concerning inflammatory glaucoma.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   159.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Ansari E, Gandhewar J (2007) Long-term efficacy and visual acuity following transscleral diode laser photocoagulation in cases of refractory and non-refractory glaucoma. Eye 21: 936–940

    Article  PubMed  CAS  Google Scholar 

  2. Beadles KA, Smith MF (1994) Inadvertent sclerotomy during transscleral Nd:YAG cyclophotocoagulation. Am J Ophthalmol 118: 669–670

    PubMed  CAS  Google Scholar 

  3. Bechrakis NE, Müller-Stolzenburg NW, Helbig H, Foerster MH (1994) Sympathetic ophthalmia following laser cyclocoagulation. Arch Ophthalmol 112: 80–84

    PubMed  CAS  Google Scholar 

  4. Benson MT, Nelson ME (1990) Cyclocryotherapy: a review over a 10-year period. Br J Ophthalmol 74: 103–105

    Article  PubMed  CAS  Google Scholar 

  5. Bloom PA, Tsai JC, Sharma K, Miller MH, Rice NSC, Hitchings RA, Khaw PT (1997) “Cyclodiode” trans-scleral diode laser cyclophotocoagulation in the treatment of advanced refractory glaucoma. Ophthalmology 104: 1508–1520

    PubMed  CAS  Google Scholar 

  6. Brindley G, Shields MB (1986) Value and limitations of cyclocryotherapy. Graefes Arch Clin Exp Ophthalmol 224: 545–548

    Article  PubMed  CAS  Google Scholar 

  7. Chang SH, Chen YC, Li CY, Wu SC (2004) Contact diode laser cyclophotocoagulation for refractory glaucoma: comparison of two treatment protocols. Can J Ophthalmol 39: 511–516

    PubMed  Google Scholar 

  8. Chen J, Cohn RA, Lin SC, Cortes AE, Alvarado JA (1997) Endoscopic photocoagulation of the ciliary body for treatment of refractory glaucomas. Am J Ophthalmol 124: 787–796

    PubMed  CAS  Google Scholar 

  9. Fankhauser F, Kwasniewska S, van der Zypen E (2004) Cyclodestructve procedure. I. Clinical and morphological aspects: a review. Ophthalmologica 218:77–95

    Article  PubMed  Google Scholar 

  10. Gaasterland DE, Pollack IP (1992) Initial experience with a new method of laser transscleral cyclophotocoagulation for ciliary ablation in severe glaucoma. Trans Am Ophthalmol Soc 90: 225–246

    PubMed  CAS  Google Scholar 

  11. Goldenberg-Cohen N, Bahar I, Ostakinski M, Lusky M, Weinberger D, Gaten DD (2005) Cyclocryotherapy versus transscleral diode laser cyclophotocoagulation for uncontrolled intraocular pressure. Ophthalmic Surg Lasers Imaging 36: 272–279

    PubMed  Google Scholar 

  12. Grüb M, Rohrbach JM, Bartz-Schmidt KU, Schlote T (2006) Transscleral diode laser cyclophotocoagulation as primary and secondary surgical treatment in primary open-angle and pseudoexfoliative glaucoma. Graefes Arch Clin Exp Ophthalmol 244: 1293–1299

    Article  Google Scholar 

  13. Hardten DR, Brown JD (1991) Malignant glaucoma after Nd:YAG cyclophotocoagulation. Am J Ophthalmol 111: 245–247

    PubMed  CAS  Google Scholar 

  14. Heinz C, Koch JM, Heiligenhaus A (2006) Transscleral diode laser cyclophotocoagulation as primary surgical treatment for secondary glaucoma in juvenile idiopathic arthritis: high failure rate after short time follow up. Br J Ophthalmol 90: 737–740

    Article  PubMed  CAS  Google Scholar 

  15. Howard GM, de Roetth AJ (1967) Histopathologic changes following cryotherapy of the rabbit ciliary body. Am J Ophthalmol 64: 700–701

    PubMed  CAS  Google Scholar 

  16. Kirwan JF, Shah P, Khaw PT (2002) Diode laser cyclophotocoagulation: role in the management of refractory pediatric glaucomas. Ophthalmology 109: 316–323

    Article  PubMed  Google Scholar 

  17. Lai JS, Tham CC, Chan JC, Lam DS (2005) Diode laser transscleral cyclophotocoagulation as primary surgical treatment for medically uncontrolled chronic angle closure glaucoma: long-term clinical outcomes. J Glaucoma 14: 114–119

    Article  PubMed  Google Scholar 

  18. Lima FE, Magacho C, Carvalho DM, Susanna R Jr, Avila MP (2004) A prospective, comparative study between endoscopic cyclophotocoagulation and the Ahmed drainage implant in refractory glaucoma. J Glaucoma 13: 233–237

    Article  PubMed  Google Scholar 

  19. Matrobattista JM, Luntz M (1996) Ciliary body ablation: where are we and how did we get here? Surv Ophthalmol 41: 193–213

    Article  Google Scholar 

  20. Neely DE, Plaqer DA (2001) Endocyclophotocoagulation for management of difficult pediatric glaucomas. J AAPOS 5: 221–229

    Article  PubMed  CAS  Google Scholar 

  21. Prost M (1983) Cyclocryotherapy for glaucoma. Evaluation of techniques. Surv Ophthalmol 28: 93–100

    Article  PubMed  CAS  Google Scholar 

  22. Schlote T, Mielke J, Zierhut M, Jean B, Thiel H-J (1998) Zyklophotokoagulation als effektive und sichere Methode zur Therapie des Sekundärglaukoms bei anteriorer, nekrotisierender Skleritis. Klin Monatsbl Augenheilkd 213: 306–308

    Article  PubMed  CAS  Google Scholar 

  23. Schlote T, Derse M, Zierhut M (2000) Transscleral diode laser cyclophotocoagulation for the treatment of refractory glaucoma secondary to inflammatory eye diseases. Br J Ophthalmol 84: 999–1003

    Article  PubMed  CAS  Google Scholar 

  24. Schlote T, Beck J, Rohrbach JM, Funk RHW (2001a) Alteration of the vascular supply in the rabbit ciliary body by transscleral diode laser cyclophotocoagulation. Graefes Arch Clin Exp Ophthalmol 239: 53–58

    Article  CAS  Google Scholar 

  25. Schlote T, Derse M, Rassmann K, Nicaeus T, Dietz K, Thiel H-J (2001b) Efficacy and safety of contact transscleral diode laser cyclophotocoagulation for advanced glaucoma. J Glaucoma 10: 294–301

    Article  CAS  Google Scholar 

  26. Schlote T, Derse M (2001c) Subconjunctival anesthesia in contact diode laser cyclophotocoagulation. Ophthalmic Surg Lasers 32: 289–293

    CAS  Google Scholar 

  27. Simmons RB, Prum BE, Shields SR, Echelmann DA, Shields MB (1994) Videographic and histologic comparison of Nd:YAG and diode laser contact transscleral cyclophotocoagulation. Am J Ophthalmol 117:337–341

    PubMed  CAS  Google Scholar 

  28. Threlkeld AB, Johnson MH (1999) Contact transscleral diode laser cyclophotocoagulation for refractory glaucoma. J Glaucoma 8: 3–7

    Article  PubMed  CAS  Google Scholar 

  29. Vesti E, Rong-Guang W, Raitta C (1992) Transillumination guided cyclocryotherapy in the treatment of secondary glaucoma. Eur J Ophthalmol 2: 190–195

    Google Scholar 

  30. Wagle NS, Freedman SF, Buckley EG, Davis JS, Biglan AW (1998) Long-term outcome of cyclocryotherapy for refractory pediatric glaucoma. Ophthalmology 105: 1921–1927

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2008 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Schlote, T. (2008). Cyclodestructive Procedures. In: Becker, M., Davis, J. (eds) Surgical Management of Inflammatory Eye Disease. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-33862-8_17

Download citation

  • DOI: https://doi.org/10.1007/978-3-540-33862-8_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-33861-1

  • Online ISBN: 978-3-540-33862-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics