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Immunoglobulin A Nephropathy

  • Reference work entry
Pediatric Nephrology

Abstract

Immunoglobulin A (IgA) nephropathy was first described in 1968 by Berger and Hinglais (1) and is now recognized as a distinct clinicopathologic entity with a higher frequency worldwide than any other primary glomerulopathy (2). It was initially considered a benign condition, but extended follow-up of patients indicated that 20–50% of adults would ultimately progress to end-stage renal failure (2, 3). Likewise, the favorable prognosis initially attributed to children with IgA nephropathy must be questioned in the light of studies (4–8).

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Authors and Affiliations

  1. Department of Pediatrics, Wakayama Medical University, Wakayama City, Japan

    Koichi Nakanishi & Norishige Yoshikawa

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  1. Koichi Nakanishi
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  2. Norishige Yoshikawa
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  1. Medical College of Wisconsin, Wisconsin, USA

    Ellis Avner (Director, Children's Research Institute, CHHS, Associate Dean for Research, Professor of Pediatrics and Physiology) (Director, Children's Research Institute, CHHS, Associate Dean for Research, Professor of Pediatrics and Physiology)

  2. Harvard Medical School, Children's Hospital Boston, 300 Longwood Avenue, Boston, Massachusetts, 02115, USA

    William Harmon (Professor of Pediatrics, Director, Pediatric Nephrology) (Professor of Pediatrics, Director, Pediatric Nephrology)

  3. Service de Néphrologie Pédiatrique Centre de référence des Maladies Rénales Héréditaires de l'Enfant et de l'Adulte (MARHEA), Hôpital Necker‐Enfants Malades, 149, rue de Sèvres, 75743, Paris Cedex 15, France

    Patrick Niaudet

  4. Department of Pediatrics Wakayama Medical University, Wakayama Medical University Hospital, 641–8510811–1, Kimiidera, Wakayama City, Japan

    Norishige Yoshikawa (Professor and Chair Pediatrician‐in‐Chief) (Professor and Chair Pediatrician‐in‐Chief)

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© 2009 Springer-Verlag Berlin Heidelberg

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Nakanishi, K., Yoshikawa, N. (2009). Immunoglobulin A Nephropathy. In: Avner, E., Harmon, W., Niaudet, P., Yoshikawa, N. (eds) Pediatric Nephrology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-76341-3_31

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  • DOI: https://doi.org/10.1007/978-3-540-76341-3_31

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-76327-7

  • Online ISBN: 978-3-540-76341-3

  • eBook Packages: MedicineReference Module Medicine

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