Zusammenfassung
Die beeindruckenden Dimensionen von Ursachen und Folgen individueller und kollektiver Aggression und Gewaltanwendung sind allseits ersichtlich. Umso erstaunlicher ist, dass dieses Thema in den psychiatrischen Lehr- und Fachbüchern bislang kaum Beachtung fand, obwohl es naheliegt anzunehmen, dass abnorme Funktionsweisen des Gehirns in erheblichem Maße zu gewalttätigem Verhalten beitragen. Im nachstehenden Kapitel wird ein Überblick über die neurobiologischen Grundlagen aggressiven Verhaltens einschließlich Genetik, über Epidemiologie, Neuropathologie, Pathophysiologie und Psycho pathologie von Aggression und Gewalt gegeben. Es folgt eine Darstellung von Gewaltneigung infolge psychischer Störungen, der Ergebnisse von Hirnstruktur- und -funktionsbildgebung und schließlich der pharmakotherapeutischen Optionen zur Behandlung krankhaft aggressiven Verhaltens. Es erscheint notwendig, dass das Themenfeld von Aggression und Gewalt stärker in die psychiatrische Lehre und Forschung integriert wird als bisher.
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Literatur
Adler L, Lehmann K, Räder K, Schünemann KF (1993) Amokläufer – kontentanalytische Untersuchung an 196 Pressemitteilungen aus industrialisierten Ländern. Fortschr Neurol Psychiat 61: 424– 433
Adler L, Marx D, Apel H, Wolfersdorf M, Hajak G (2006) Zur Stabilitat des »Amoklaufer«-Syndroms. Fortschr Neurol Psychiatr 74: 582– 590
Archer J (2006) Testosterone and human aggression: an evaluation of the challenge hypothesis. Neurosci Biobehav Rev 30: 319–345
Arseneault L, Moffitt TE, Caspi A et al. (2000) Mental disorders and violence in a total birth cohort: results from the Dunedin Study. Arch Gen Psychiatry 57: 979–986
Banks T, Dabbs JM Jr (1996) Salivary testosterone and cortisol in a delinquent and violent urban subculture. J Soc Psychol 136: 49–56
Barratt ES, Stanford MS, Dowdy L et al. (1999) Impulsive and premeditated aggression: a factor analysis of self-reported acts. Psychiatry Res 86: 163–173
Bhatt S,Siegel A (2006) Potentiating role of interleukin 2 (IL-2) receptors in the midbrain periaqueductal gray (PAG) upon defensive rage behavior in the cat: role of neurokinin NK(1) receptors. Behav Brain Res 167: 251–260
Binks CA, Fenton M, McCarthy L et al. (2006) Pharmacological interventions for people with borderline personality disorder. Cochrane Database Syst Rev CD005653
Birbaumer N, Veit R, Lotze M et al. (2005) Deficient fear conditioning in psychopathy: a functional magnetic resonance imaging study. Arch Gen Psychiatry 62: 799–805
Bogerts B (1997) The temporolimbic system theory of positive schizophrenic symptoms. Schizophr Bull 23: 423–435
Bogerts B (1999) The neuropathology of schizophrenic diseases: historical aspects and present knowledge. Eur Arch Psychiatry Clin Neurosci 249 Suppl 4: 2–13
Bogerts B (2008) Funktionell-neuroanatomische und neuropathologische Grundlagen psychischer Erkrankungen. In: Möller HJ (Hrsg) Psychiatrie und Psychotherapie, Bd. 2. Springer, Berlin Heidelberg New York Tokio, S 109–128
Book AS, Starzyk KB,Quinsey VL (2001) The relationship between testosterone and aggression: a meta-analysis. Aggression and Violent Behavior 6: 579–599
Braham LG, Trower P,Birchwood M (2004) Acting on command hallucinations and dangerous behavior: a critique of the major findings in the last decade. Clin Psychol Rev 24: 513–528
Buckholtz JW, Treadway MT, Cowan RL et al. (2010) Mesolimbic dopamine reward system hypersensitivity in individuals with psychopathic traits. Nat Neurosci 13: 419–421
Bufkin JL, Luttrell VR (2005) Neuroimaging studies of aggressive and violent behavior: current findings and implications for criminology and criminal justice. Trauma Violence Abuse 6: 176–191
Caspi A, Moffitt TE (2006) Gene-environment interactions in psychiatry: joining forces with neuroscience. Nat Rev Neurosci 7: 583– 590
Caspi A, McClay J, Moffitt TE et al. (2002) Role of genotype in the cycle of violence in maltreated children. Science 297: 851–854
Chemtob CM, Novaco RW, Hamada RS et al. (1997) Anger regulation deficits in combat-related posttraumatic stress disorder. J Trauma Stress 10: 17–36
Citrome L, Levine J, Allingham B (2000) Changes in use of valproate and other mood stabilizers for patients with schizophrenia from 1994 to 1998. Psychiatr Serv 51: 634–638
Citrome L, Nolan KA,Volavka J (2004) Science-based treatment of aggression and agitation. In: Kingston FD (ed) The science, treatment, and prevention of antisocial behaviors, Vol. 2. Civic Research Institute, New York
Cloninger CR, Sigvardsson S, Bohman M,von Knorring AL (1982) Predisposition to petty criminality in Swedish adoptees. II. Cross-fostering analysis of gene-environment interaction. Arch Gen Psychiatry 39: 1242–1247
Coccaro EF, Bergeman CS,McClearn GE (1993) Heritability of irritable impulsiveness: a study of twins reared together and apart. Psychiatry Res 48: 229–242
Coccaro EF, Kavoussi RJ (1997) Fluoxetine and impulsive aggressive behavior in personality-disordered subjects. Arch Gen Psychiatry 54: 1081–1088
Coccaro EF, Kavoussi RJ, Berman ME, Lish JD (1998) Intermittent explosive disorder-revised: development, reliability, and validity of research criteria. Compr Psychiatry 39: 368–376
Coccaro EF, Lee RJ,Kavoussi RJ (2009) A double-blind, randomized, placebo-controlled trial of fluoxetine in patients with intermittent explosive disorder. J Clin Psychiatry 70: 653–662
Coccaro EF, McCloskey MS, Fitzgerald DA, Phan KL (2007) Amygdala and orbitofrontal reactivity to social threat in individuals with impulsive aggression. Biol Psychiatry 62: 168–178
Collins JJ, Bailey SL (1990) Relationship of mood disorders to violence. J Nerv Ment Dis 178: 44–47
Collins PJ, Larkin EP, Shubsachs AP (1991) Lithium carbonate in chronic schizophrenia--a brief trial of lithium carbonate added to neuroleptics for treatment of resistant schizophrenic patients. Acta Psychiatr Scand 84: 150–154
Conacher GN, Workman DG (1989) Violent crime possibly associated with anabolic steroid use. Am J Psychiatry 146: 679
Cornell DG, Warren J, Hawk G et al. (1996) Psychopathy in instrumental and reactive violent offenders. J Consult Clin Psychol 64: 783– 790
Cowdry RW, Gardner DL (1988) Pharmacotherapy of borderline personality disorder. Alprazolam, carbamazepine, trifluoperazine, and tranylcypromine. Arch Gen Psychiatry 45: 111–119
Dabbs JM, Jr., Frady RL et al. (1987) Saliva testosterone and criminal violence in young adult prison inmates. Psychosom Med 49: 174–182
Davidge KM, Atkinson L, Douglas L et al. (2004) Association of the serotonin transporter and 5HT1Dbeta receptor genes with extreme, persistent and pervasive aggressive behaviour in children. Psychiatr Genet 14: 143–146
de Oliveira-Souza R, Hare RD, Bramati IE et al. (2008) Psychopathy as a disorder of the moral brain: fronto-temporo-limbic grey matter reductions demonstrated by voxel-based morphometry. Neuroimage 40: 1202–1213
Deeley Q, Daly E, Surguladze S et al. (2006) Facial emotion processing in criminal psychopathy. Preliminary functional magnetic resonance imaging study. Br J Psychiatry 189: 533–539
DiLalla DL, Carey G, Gottesman II, Bouchard TJ Jr. (1996) Heritability of MMPI personality indicators of psychopathology in twins reared apart. J Abnorm Psychol 105: 491–499
Dixon L, Hamilton-Giachritsis C, Browne K (2008) Classifying partner femicide. J Interpers Violence 23: 74–93
Donovan SJ, Stewart JW, Nunes EV et al. (2000) Divalproex treatment for youth with explosive temper and mood lability: a doubleblind, placebo-controlled crossover design. Am J Psychiatry 157: 818–820
Dressing H, Gass P, Kuhner C,Habermeyer E (2005) [Psychiatric signifi- cance of stalking]. Gesundheitswesen 67: 869–871
Dressing H, Kuehner C, Gass P (2006) The epidemiology and characteristics of stalking. Curr Opin Psychiatry 19: 395–399
Dressing H, Kuhner C, Gass P (2007) Multiaxial classification of stalking. Guidelines for the assessment of criminal liability and prognosis. Nervenarzt 78: 764, 766–768, 770–762
Elbogen EB, Johnson SC (2009) The intricate link between violence and mental disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Arch Gen Psychiatry 66: 152–161
Eronen M, Hakola P,Tiihonen J (1996 a) Mental disorders and homicidal behavior in Finland. Arch Gen Psychiatry 53: 497–501
Eronen M, Tiihonen J,Hakola P (1996 b) Schizophrenia and homicidal behavior. Schizophr Bull 22: 83–89
Fayyad J, De Graaf R, Kessler R et al. (2007) Cross-national prevalence and correlates of adult attention-deficit hyperactivity disorder. Br J Psychiatry 190: 402–409
Fazel S, Grann M, Carlstrom E et al. (2009) Risk factors for violent crime in Schizophrenia: a national cohort study of 13,806 patients. J Clin Psychiatry 70: 362–369
Fazel S, Gulati G, Linsell L et al. (2009) Schizophrenia and violence: systematic review and meta-analysis. PLoS Med 6: e1000120
Flor H, Birbaumer N, Hermann C et al. (2002) Aversive Pavlovian conditioning in psychopaths: peripheral and central correlates. Psychophysiology 39: 505–518
Freeman TW, Roca V (2001) Gun use, attitudes toward violence, and aggression among combat veterans with chronic posttraumatic stress disorder. J Nerv Ment Dis 189: 317–320
Freeman TW, Roca V, Kimbrell T (2003) A survey of gun collection and use among three groups of veteran patients admitted to veterans affairs hospital treatment programs. South Med J 96: 240–243
Freud S (1920) Jenseits des Lustprinzips. Fischer Verlag, Frankfurt a. M.
Freud S (1930) Das Unbehagen in der Kultur. Internationaler Psychoanalytischer Verlag, Wien
Freud S (1933) Warum Krieg? Briefwechsel mit Albert Einstein. Diogenes, Zürich
Fromm E (1973) The Anatomy of Human Destructiveness. Holt, Rinehart and Winston, New York
Giotakos O, Markianos M, Vaidakis N,Christodoulou GN (2004) Sex hormones and biogenic amine turnover of sex offenders in relation to their temperament and character dimensions. Psychiatry Res 127: 185–193
Gladue BA (1991) Qualitative and quantitative sex differences in selfreported aggressive behavioural charteristics. Psychol Rep. 68: 675–684
Goff DC, Keefe R, Citrome L et al. (2007) Lamotrigine as add-on therapy in schizophrenia: results of 2 placebo-controlled trials. J Clin Psychopharmacol 27: 582–589
Goldsmith HH, Gottesman II (1981) Origins of variation in behavioral style: a longitudinal study of temperament in young twins. Child Dev 52: 91–103
Goodall J (1971) In the shadow of man. William Collins Sons & Co., London
Goodman WK, Ward H, Kablinger A, Murphy T (1997) Fluvoxamine in the treatment of obsessive-compulsive disorder and related conditions. J Clin Psychiatry 58 Suppl 5: 32–49
Gordon HL, Baird AA, End A (2004) Functional differences among those high and low on a trait measure of psychopathy. Biol Psychiatry 56: 516–521
Gotz MJ, Johnstone EC, Ratcliffe SG (1999) Criminality and antisocial behaviour in unselected men with sex chromosome abnormalities. Psychol Med 29: 953–962
Gutknecht L, Jacob C, Strobel A et al. (2007) Tryptophan hydroxylase- 2 gene variation influences personality traits and disorders related to emotional dysregulation. Int J Neuropsychopharmacol 10: 309–320
Citrome L, Nolan KA,Volavka J (2004) Science-based treatment of aggression and agitation. In: Kingston FD (ed) The science, treatment, and prevention of antisocial behaviors, Vol. 2. Civic Research Institute, New York
Cloninger CR, Sigvardsson S, Bohman M,von Knorring AL (1982) Predisposition to petty criminality in Swedish adoptees. II. Cross-fostering analysis of gene-environment interaction. Arch Gen Psychiatry 39: 1242–1247
Coccaro EF, Bergeman CS,McClearn GE (1993) Heritability of irritable impulsiveness: a study of twins reared together and apart. Psychiatry Res 48: 229–242
Coccaro EF, Kavoussi RJ (1997) Fluoxetine and impulsive aggressive behavior in personality-disordered subjects. Arch Gen Psychiatry 54: 1081–1088
Coccaro EF, Kavoussi RJ, Berman ME, Lish JD (1998) Intermittent explosive disorder-revised: development, reliability, and validity of research criteria. Compr Psychiatry 39: 368–376
Coccaro EF, Lee RJ,Kavoussi RJ (2009) A double-blind, randomized, placebo-controlled trial of fluoxetine in patients with intermittent explosive disorder. J Clin Psychiatry 70: 653–662
Coccaro EF, McCloskey MS, Fitzgerald DA, Phan KL (2007) Amygdala and orbitofrontal reactivity to social threat in individuals with impulsive aggression. Biol Psychiatry 62: 168–178
Collins JJ, Bailey SL (1990) Relationship of mood disorders to violence. J Nerv Ment Dis 178: 44–47
Collins PJ, Larkin EP, Shubsachs AP (1991) Lithium carbonate in chronic schizophrenia--a brief trial of lithium carbonate added to neuroleptics for treatment of resistant schizophrenic patients. Acta Psychiatr Scand 84: 150–154
Conacher GN, Workman DG (1989) Violent crime possibly associated with anabolic steroid use. Am J Psychiatry 146: 679
Cornell DG, Warren J, Hawk G et al. (1996) Psychopathy in instrumental and reactive violent offenders. J Consult Clin Psychol 64: 783– 790
Cowdry RW, Gardner DL (1988) Pharmacotherapy of borderline personality disorder. Alprazolam, carbamazepine, trifluoperazine, and tranylcypromine. Arch Gen Psychiatry 45: 111–119
Dabbs JM, Jr., Frady RL et al. (1987) Saliva testosterone and criminal violence in young adult prison inmates. Psychosom Med 49: 174–182
Davidge KM, Atkinson L, Douglas L et al. (2004) Association of the serotonin transporter and 5HT1Dbeta receptor genes with extreme, persistent and pervasive aggressive behaviour in children. Psychiatr Genet 14: 143–146
de Oliveira-Souza R, Hare RD, Bramati IE et al. (2008) Psychopathy as a disorder of the moral brain: fronto-temporo-limbic grey matter reductions demonstrated by voxel-based morphometry. Neuroimage 40: 1202–1213
Deeley Q, Daly E, Surguladze S et al. (2006) Facial emotion processing in criminal psychopathy. Preliminary functional magnetic resonance imaging study. Br J Psychiatry 189: 533–539
DiLalla DL, Carey G, Gottesman II, Bouchard TJ Jr. (1996) Heritability of MMPI personality indicators of psychopathology in twins reared apart. J Abnorm Psychol 105: 491–499
Dixon L, Hamilton-Giachritsis C, Browne K (2008) Classifying partner femicide. J Interpers Violence 23: 74–93
Donovan SJ, Stewart JW, Nunes EV et al. (2000) Divalproex treatment for youth with explosive temper and mood lability: a doubleblind, placebo-controlled crossover design. Am J Psychiatry 157: 818–820
Dressing H, Gass P, Kuhner C,Habermeyer E (2005) [Psychiatric signifi- cance of stalking]. Gesundheitswesen 67: 869–871
Dressing H, Kuehner C, Gass P (2006) The epidemiology and characteristics of stalking. Curr Opin Psychiatry 19: 395–399
Dressing H, Kuhner C, Gass P (2007) Multiaxial classification of stalking. Guidelines for the assessment of criminal liability and prognosis. Nervenarzt 78: 764, 766–768, 770–762
Elbogen EB, Johnson SC (2009) The intricate link between violence and mental disorder: results from the National Epidemiologic Survey on Alcohol and Related Conditions. Arch Gen Psychiatry 66: 152–161
Eronen M, Hakola P,Tiihonen J (1996 a) Mental disorders and homicidal behavior in Finland. Arch Gen Psychiatry 53: 497–501
Eronen M, Tiihonen J,Hakola P (1996 b) Schizophrenia and homicidal behavior. Schizophr Bull 22: 83–89
Fayyad J, De Graaf R, Kessler R et al. (2007) Cross-national prevalence and correlates of adult attention-deficit hyperactivity disorder. Br J Psychiatry 190: 402–409
Fazel S, Grann M, Carlstrom E et al. (2009) Risk factors for violent crime in Schizophrenia: a national cohort study of 13,806 patients. J Clin Psychiatry 70: 362–369
Fazel S, Gulati G, Linsell L et al. (2009) Schizophrenia and violence: systematic review and meta-analysis. PLoS Med 6: e1000120
Flor H, Birbaumer N, Hermann C et al. (2002) Aversive Pavlovian conditioning in psychopaths: peripheral and central correlates. Psychophysiology 39: 505–518
Freeman TW, Roca V (2001) Gun use, attitudes toward violence, and aggression among combat veterans with chronic posttraumatic stress disorder. J Nerv Ment Dis 189: 317–320
Freeman TW, Roca V, Kimbrell T (2003) A survey of gun collection and use among three groups of veteran patients admitted to veterans affairs hospital treatment programs. South Med J 96: 240–243
Freud S (1920) Jenseits des Lustprinzips. Fischer Verlag, Frankfurt a. M.
Freud S (1930) Das Unbehagen in der Kultur. Internationaler Psychoanalytischer Verlag, Wien
Freud S (1933) Warum Krieg? Briefwechsel mit Albert Einstein. Diogenes, Zürich
Fromm E (1973) The Anatomy of Human Destructiveness. Holt, Rinehart and Winston, New York
Giotakos O, Markianos M, Vaidakis N,Christodoulou GN (2004) Sex hormones and biogenic amine turnover of sex offenders in relation to their temperament and character dimensions. Psychiatry Res 127: 185–193
Gladue BA (1991) Qualitative and quantitative sex differences in selfreported aggressive behavioural charteristics. Psychol Rep. 68: 675–684
Goff DC, Keefe R, Citrome L et al. (2007) Lamotrigine as add-on therapy in schizophrenia: results of 2 placebo-controlled trials. J Clin Psychopharmacol 27: 582–589
Goldsmith HH, Gottesman II (1981) Origins of variation in behavioral style: a longitudinal study of temperament in young twins. Child Dev 52: 91–103
Goodall J (1971) In the shadow of man. William Collins Sons & Co., London
Goodman WK, Ward H, Kablinger A, Murphy T (1997) Fluvoxamine in the treatment of obsessive-compulsive disorder and related conditions. J Clin Psychiatry 58 Suppl 5: 32–49
Gordon HL, Baird AA, End A (2004) Functional differences among those high and low on a trait measure of psychopathy. Biol Psychiatry 56: 516–521
Gotz MJ, Johnstone EC, Ratcliffe SG (1999) Criminality and antisocial behaviour in unselected men with sex chromosome abnormalities. Psychol Med 29: 953–962
Gutknecht L, Jacob C, Strobel A et al. (2007) Tryptophan hydroxylase- 2 gene variation influences personality traits and disorders related to emotional dysregulation. Int J Neuropsychopharmacol 10: 309–320
Hampden-Turner D (1981) Maps of the Mind. Macmillan, New York, p 81
Hare RD (1991) The Psychopathy Checklist – Revised. Multi-Health Systems, Toronto, ON
Hare RD, Clark D, Grann M, Thornton D (2000) Psychopathy and the predictive validity of the PCL-R: an international perspective. Behav Sci Law 18: 623–645
Hassanain M, Bhatt S, Zalcman S,Siegel A (2005) Potentiating role of interleukin-1beta (IL-1beta) and IL-1beta type 1 receptors in the medial hypothalamus in defensive rage behavior in the cat. Brain Res 1048: 1–11
Hennig J, Reuter M, Netter P et al. (2005) Two types of aggression are differentially related to serotonergic activity and the A779C TPH polymorphism. Behav Neurosci 119: 16–25
Herpertz SC, Dietrich TM, Wenning B et al. (2001) Evidence of abnormal amygdala functioning in borderline personality disorder: a functional MRI study. Biol Psychiatry 50: 292–298
Hiley-Young B, Blake DD, Abueg FR et al. (1995) Warzone violence in Vietnam: an examination of premilitary, military, and postmilitary factors in PTSD in-patients. J Trauma Stress 8: 125–141
Hollander E, Allen A, Lopez RP et al. (2001) A preliminary doubleblind, placebo-controlled trial of divalproex sodium in borderline personality disorder. J Clin Psychiatry 62: 199–203
Hollander E, Swann AC, Coccaro EF et al. (2005) Impact of trait impulsivity and state aggression on divalproex versus placebo response in borderline personality disorder. Am J Psychiatry 162: 621–624
Jacobs PA, Brunton M, Melville MM et al. (1965) Aggressive behavior, mental sub-normality and the XYY male. Nature 208: 1351–1352
Kessler RC, Adler L, Barkley R et al. (2006 a) The prevalence and correlates of adult ADHD in the United States: results from the National Comorbidity Survey Replication. Am J Psychiatry 163: 716–723
Kessler RC, Coccaro EF, Fava M, Jaeger S, Jin R,Walters E (2006 b) The prevalence and correlates of DSM-IV intermittent explosive disorder in the National Comorbidity Survey Replication. Arch Gen Psychiatry 63: 669–678
Kiehl KA, Smith AM, Hare RD et al. (2001) Limbic abnormalities in affective processing by criminal psychopaths as revealed by functional magnetic resonance imaging. Biol Psychiatry 50: 677–684
Kienlen KK, Birmingham DL, Solberg KB et al. (1997) A comparative study of psychotic and nonpsychotic stalking. J Am Acad Psychiatry Law 25: 317–334
Kim-Cohen J, Caspi A, Taylor A et al. (2006) MAOA, maltreatment, and gene-environment interaction predicting children's mental health: new evidence and a meta-analysis. Mol Psychiatry 11: 903–913
Klotz F, Garle M, Granath F,Thiblin I (2006) Criminality among individuals testing positive for the presence of anabolic androgenic steroids. Arch Gen Psychiatry 63: 1274–1279
Krakowski MI, Czobor P, Citrome L et al. (2006) Atypical antipsychotic agents in the treatment of violent patients with schizophrenia and schizoaffective disorder. Arch Gen Psychiatry 63: 622–629
Krug ET, Dahlberg LL, Mercy JA et al. (2002) World report on violence and health. Geneva, World Health Organization
Langbehn DR,Cadoret RJ (2001) The adult antisocial syndrome with and without antecedent conduct disorder: comparisons from an adoption study. Compr Psychiatry 42: 272–282
Lieb K, Zanarini MC, Schmahl C et al. (2004) Borderline personality disorder. Lancet 364: 453–461
Lilienfeld SO, Andrews BP (1996) Development and preliminary validation of a self-report measure of psychopathic personality traits in noncriminal populations. J Pers Assess 66: 488–524
Linehan MM (1987) Dialectical behavior therapy for borderline personality disorder. Theory and method. Bull Menninger Clin 51: 261–276
Link BG, Stueve A, Phelan J (1998) Psychotic symptoms and violent behaviors: probing the components of »threat/control-override« symptoms. Soc Psychiatry Psychiatr Epidemiol 33 Suppl 1: S55– 60
Logan C, Blackburn R (2009) Mental disorder in violent women in secure settings: potential relevance to risk for future violence. Int J Law Psychiatry 32: 31–38
Lorenz K (1963) Das sogenannte Böse. Dr. G. Borotha-Schoeler Verlag, Wien
Maclean PD (1952) Some psychiatric implications of physiological studies on frontotemporal portion of limbic system (visceral brain). Electroencephalogr Clin Neurophysiol 4: 407–418
Mannuzza S, Klein RG, Bessler A et al. (1993) Adult outcome of hyperactive boys. Educational achievement, occupational rank, and psychiatric status. Arch Gen Psychiatry 50: 565–576
Mannuzza S, Klein RG, Bessler A et al. (1998) Adult psychiatric status of hyperactive boys grown up. Am J Psychiatry 155: 493–498
Mark VH, Ervin FR (1970) Violence and the brain. Harper & Row Publ, New York
McElroy SL (1999) Recognition and treatment of DSM-IV intermittent explosive disorder. J Clin Psychiatry 60 Suppl 15: 12–16
Meloy JR (1999) Stalking. An old behavior, a new crime. Psychiatr Clin North Am 22: 85–99
Meloy JR, Fisher H (2005) Some thoughts on the neurobiology of stalking. J Forensic Sci 50: 1472–1480
Meloy JR, Gothard S (1995) Demographic and clinical comparison of obsessional followers and offenders with mental disorders. Am J Psychiatry 152: 258–263
Meloy JR, Davis B, Lovette J (2001) Risk factors for violence among stalkers. J Threat Assess 1: 3–16
Meyer-Lindenberg, A Buckholtz JW, Kolachana B et al. (2006) Neural mechanisms of genetic risk for impulsivity and violence in humans. Proc Natl Acad Sci U S A 103: 6269–6274
Miller NE, Dollard JC, Doob LW et al. (1939) Frustration and Aggression. Yale University Press, New Haven, Connecticut
Moffitt TE (1990) Juvenile delinquency and attention deficit disorder: boys' developmental trajectories from age 3 to age 15. Child Dev 61: 893–910
Moffitt TE, Melchior M (2007) Why does the worldwide prevalence of childhood attention deficit hyperactivity disorder matter? Am J Psychiatry 164: 856–858
Morrison KA (2001) Predicting violent behavior in stalkers: a preliminary investigation of Canadian cases in criminal harassment. J Forensic Sci 46: 1403–1410
Mullen PE, Pathe M, Purcell R,Stuart GW (1999) Study of stalkers. Am J Psychiatry 156: 1244–1249
Mullen PE, Burgess P, Wallace C et al. (2000) Community care and criminal offending in schizophrenia. Lancet 355: 614–617
Mullen PE, Mackenzie R, Ogloff JR et al. (2006) Assessing and managing the risks in the stalking situation. J Am Acad Psychiatry Law 34: 439–450
Muller JL, Sommer M, Wagner V et al. (2003) Abnormalities in emotion processing within cortical and subcortical regions in criminal psychopaths: evidence from a functional magnetic resonance imaging study using pictures with emotional content. Biol Psychiatry 54: 152–162
Narabayashi H, Nagao T, Saito Y et al. (1963) Stereotaxic amygdalotomy for behavior disorders. Arch Neurol 9: 1–16
Narabayashi H, Uno M (1966) Long range results of stereotaxic amygdalotomy for behavior disorders. Confin Neurol 27: 168–171
Norra C, Mrazek M, Tuchtenhagen F, Gobbele R, Buchner H, Sass H,Herpertz SC (2003) Enhanced intensity dependence as a marker of low serotonergic neurotransmission in borderline personality disorder. J Psychiatr Res 37: 23–33
O'Connor DB, Archer J,Wu FC (2004) Effects of testosterone on mood, aggression, and sexual behavior in young men: a double-blind, placebo-controlled, cross-over study. J Clin Endocrinol Metab 89: 2837–2845
Okuma T, Yamashita I, Takahashi R et al. (1989) A double-blind study of adjunctive carbamazepine versus placebo on excited states of schizophrenic and schizoaffective disorders. Acta Psychiatr Scand 80: 250–259
Oquendo MA, Friend JM, Halberstam B et al. (2003) Association of comorbid posttraumatic stress disorder and major depression with greater risk for suicidal behavior. Am J Psychiatry 160: 580–582
Oquendo M, Brent DA, Birmaher B et al. (2005) Posttraumatic stress disorder comorbid with major depression: factors mediating the association with suicidal behavior. Am J Psychiatry 162: 560–566
Paris J (2009) The treatment of borderline personality disorder: implications of research on diagnosis, etiology, and outcome. Annu Rev Clin Psychol 5: 277–290
Paris J, Zweig-Frank H, Kin NM et al. (2004) Neurobiological correlates of diagnosis and underlying traits in patients with borderline personality disorder compared with normal controls. Psychiatry Res 121: 239–252
Pathe M, Mullen PE (1997) The impact of stalkers on their victims. Br J Psychiatry 170: 12–17
Pathe MT, Mullen PE, Purcell R (2002) Patients who stalk doctors: their motives and management. Med J Aust 176: 335–338
Peter E, Bogerts B (2010) Epidemiologie und Psychopathologie des Amoklaufes. Erste Ergebnisse einer Analyse von Strafakten von 27 Amkoläufen. Nervenarzt (eingereicht)
Ploog D (1975) Biologische Grundlagen aggressiven Verhaltens. Psychiatrische und ethologische Aspekte abnormen Verhalten. In: Kranz H, Heinrich K (Hrsg) 1. Düsseldorfer Symposium. Thieme, Stuttgart, S 49–77
Podlowski A, Gregory SL,Blackwood NJ (2008) Persistent violent offending among adult men: A critical review of neuroimaging data. In: Hodgins S, Viding E und Plodowski A (eds) The neurobiological basis of violence: science and rehabilitation. Oxford University Press, Oxford, pp 137–155
Prakash R (1985) Lithium-responsive schizophrenia: case reports. J Clin Psychiatry 46: 141–142
Purcell R, Pathe M, Mullen PE (2004) Stalking: defining and prosecuting a new category of offending. Int J Law Psychiatry 27: 157– 169
Putkonen A, Ryynanen OP, Eronen M, Tiihonen J (2002) The quantitative risk of violent crime and criminal offending: a case-control study among the offspring of recidivistic Finnish homicide offenders. Acta Psychiatr Scand Suppl 54–57
Putkonen A, Ryynanen OP, Eronen M,Tiihonen J (2007) Transmission of violent offending and crime across three generations. Soc Psychiatry Psychiatr Epidemiol 42: 94–99
Raine A, Ishikawa SS, Arce E et al. (2004) Hippocampal structural asymmetry in unsuccessful psychopaths. Biol Psychiatry 55: 185– 191
Raine A, Lencz T, Bihrle S et al. (2000) Reduced prefrontal gray matter volume and reduced autonomic activity in antisocial personality disorder. Arch Gen Psychiatry 57: 119–127; discussion 128–119
Reif A, Rosler M, Freitag CM et al. (2007) Nature and nurture predispose to violent behavior: serotonergic genes and adverse childhood environment. Neuropsychopharmacology 32: 2375–2383
Reist C, Nakamura K, Sagart E et al. (2003) Impulsive aggressive behavior: open-label treatment with citalopram. J Clin Psychiatry 64: 81–85
Resnick HS, Foy DW, Donahoe CP, Miller EN (1989) Antisocial behavior and post-traumatic stress disorder in Vietnam veterans. J Clin Psychol 45: 860–866
Retz W, Retz-Junginger P, Supprian T et al. (2004) Association of serotonin transporter promoter gene polymorphism with violence: relation with personality disorders, impulsivity, and childhood ADHD psychopathology. Behav Sci Law 22: 415–425
Retz W, Freitag CM, Retz-Junginger P et al. (2008) A functional serotonin transporter promoter gene polymorphism increases ADHD symptoms in delinquents: interaction with adverse childhood environment. Psychiatry Res 158: 123–131
Rhee SH,Waldman ID (2002) Genetic and environmental influences on antisocial behavior: a meta-analysis of twin and adoption studies. Psychol Bull 128: 490–529
Rilling JK, Glenn AL, Jairam MR et al. (2007) Neural correlates of social cooperation and non-cooperation as a function of psychopathy. Biol Psychiatry 61: 1260–1271
Rinne T, van den Brink W, Wouters L, van Dyck R (2002) SSRI treatment of borderline personality disorder: a randomized, placebo-controlled clinical trial for female patients with borderline personality disorder. Am J Psychiatry 159: 2048–2054
Rosenfeld B (2003) Recidivism in stalking and obsessional harassment. Law Hum Behav 27: 251–265
Rosenfeld B, Harmon R (2002) Factors associated with violence in stalking and obsessional harassment cases. Crim Just Behav 29: 671–691
Rösler M,Retz W (2008) ADHS, Antisoziale Persönlichkeitsstörung und Delinquenz. Zeitschrift für Psychiatrie, Psychologie und Psychotherapie 56: 121–132
Rosler M, Retz W, Retz-Junginger P et al. (2004) Prevalence of attention deficit-/hyperactivity disorder (ADHD) and comorbid disorders in young male prison inmates. Eur Arch Psychiatry Clin Neurosci 254: 365–371
Rujescu D, Giegling I, Sato T et al. (2003) Genetic variations in tryptophan hydroxylase in suicidal behavior: analysis and meta-analysis. Biol Psychiatry 54: 465–473
Rummel RJ (1994) Death by Government. Transaction Publishers, New Brunswick/NJ
Rummel RJ (1997) Statistics of democide: genocide and mass murder since 1900. Transaction Publishers, Rutgers University, New Brunswick/NJ
Salzman C, Wolfson AN, Schatzberg A et al. (1995) Effect of fluoxetine on anger in symptomatic volunteers with borderline personality disorder. J Clin Psychopharmacol 15: 23–29
Sansone RA, Sansone LA (2009) Borderline personality and criminality. Psychiatry (Edgmont) 6: 16–20
Schanda H (2006) Untersuchungen zur Frage des Zusammenhangs zwischen Psychosen und Kriminalitat/Gewalttatigkeit – Studiendesigns, methodische Probleme, Ergebnisse. Fortschr Neurol Psychiatr 74: 85–100
Schiltz K, Witzel JG, Bausch-Hölterhoff J, Bogerts B (2010) Hirnpathologische Veränderungen bei Gewaltdelinquenz – sechs Kasuistiken und Literaturüberblick. In: Müller JL (Hrsg) Neurobiologie forensisch-relevanter Störungen. Kohlhammer, Stuttgart, S 85– 95
Schmahl C, Bohus M, Esposito F et al. (2006) Neural correlates of antinociception in borderline personality disorder. Arch Gen Psychiatry 63: 659–667
Schneider F, Habel U, Kessler C et al. (2000) Functional imaging of conditioned aversive emotional responses in antisocial personality disorder. Neuropsychobiology 42: 192–201
Schoenfeld FB, Marmar CR, Neylan TC (2004) Current concepts in pharmacotherapy of posttraumatic stress disorder. Psychiatr Serv 55: 519–531
Schünemann KF (1992) Über nicht kulturgebundene Amokläufe – Eine inhaltsanalytische Untersuchung von 196 Fällen. Georg-August- Universität, Göttingen, FB Medizin
Shalev A, Hermesh H,Munitz H (1987) Severe akathisia causing neuroleptic failure: an indication for lithium therapy in schizophrenia? Acta Psychiatr Scand 76: 715–718
Sheard MH, Marini JL, Bridges CI, Wagner E (1976) The effect of lithium on impulsive aggressive behavior in man. Am J Psychiatry 133: 1409–1413
Sherman MD, Sautter F, Jackson MH et al. (2006) Domestic violence in veterans with posttraumatic stress disorder who seek couples therapy. J Marital Fam Ther 32: 479–490
Siegel A, Bhatt S, Bhatt R, Zalcman SS (2007) The neurobiological bases for development of pharmacological treatments of aggressive disorders. Curr Neuropharmacol 5: 135–147
Siever LJ (2008) Neurobiology of aggression and violence. Am J Psychiatry 165: 429–442
Sinclair HC, Frieze IH (2000) Initial courtship behavior and stalking: how should we draw the line? Violence Vict 15: 23–40
Skodol AE, Gunderson JG, Pfohl B et al. (2002) The borderline diagnosis I: psychopathology, comorbidity, and personality structure. Biol Psychiatry 51: 936–950
Swanson JW, Swartz MS, Van Dorn RA et al. (2006) A national study of violent behavior in persons with schizophrenia. Arch Gen Psychiatry 63: 490–499
Tariot PN, Erb R, Podgorski CA et al. (1998) Efficacy and tolerability of carbamazepine for agitation and aggression in dementia. Am J Psychiatry 155: 54–61
Taylor FB, Lowe K, Thompson C et al. (2006) Daytime prazosin reduces psychological distress to trauma specific cues in civilian trauma posttraumatic stress disorder. Biol Psychiatry 59: 577–581
Thiblin I, Parlklo T (2002) Anabolic androgenic steroids and violence. Acta Psychiatr Scand Suppl 125–128
Tjaden PG, Thoennes N (2001) Coworker violence and Gender. Findings from the National Violence Against Women Survey. Am J Med 20: 85–89
Torgersen S, Lygren S, Oien PA et al. (2000) A twin study of personality disorders. Compr Psychiatry 41: 416–425
Vartiainen H, Tiihonen J, Putkonen A et al. (1995) Citalopram, a selective serotonin reuptake inhibitor, in the treatment of aggression in schizophrenia. Acta Psychiatr Scand 91: 348–351
Veit R, Flor H, Erb M et al. (2002) Brain circuits involved in emotional learning in antisocial behavior and social phobia in humans. Neurosci Lett 328: 233–236
Vermeiren R (2003) Psychopathology and delinquency in adolescents: a descriptive and developmental perspective. Clin Psychol Rev 23: 277–318
Viding E, Fontaine NM, Oliver BR, Plomin R (2009) Negative parental discipline, conduct problems and callous-unemotional traits: monozygotic twin differences study. Br J Psychiatry 195: 414– 419
Virkkunen M, Kallio E, Rawlings R et al. (1994 a) Personality profiles and state aggressiveness in Finnish alcoholic, violent offenders, fire setters, and healthy volunteers. Arch Gen Psychiatry 51: 28– 33
Virkkunen M, Rawlings R, Tokola R et al. (1994 b) CSF biochemistries, glucose metabolism, and diurnal activity rhythms in alcoholic, violent offenders, fire setters, and healthy volunteers. Arch Gen Psychiatry 51: 20–27
Virkkunen M, Goldman D, Nielsen DA, Linnoila M (1995) Low brain serotonin turnover rate (low CSF 5-HIAA) and impulsive violence. J Psychiatry Neurosci 20: 271–275
Volavka J (2002) Neurobiology of Violence. American Psychiatric Publishing, Washington, DC
Volavka J, Zito JM, Vitrai J,Czobar P (1993) Clozapine effects on hostility and aggression in schizophrenia. J Clin Psychopharmacol 13: 287–289
Volavka J, Czobor P, Nolan K et al. (2004) Overt aggression and psychotic symptoms in patients with schizophrenia treated with clozapine, olanzapine, risperidone, or haloperidol. J Clin Psychopharmacol 24: 225–228
Walker LE (2006) Battered woman syndrome: empirical findings. Ann N Y Acad Sci 1087: 142–157
Yang Y, Raine A, Lencz T et al. (2005) Volume reduction in prefrontal gray matter in unsuccessful criminal psychopaths. Biol Psychiatry 57: 1103–1108
Yarvis RM (1990) Axis I and Axis II diagnostic parameters of homicide. Bull Am Acad Psychiatry Law 18: 249–269
Zalsman G, Frisch A, Bromberg M et al. (2001) Family-based association study of serotonin transporter promoter in suicidal adolescents: no association with suicidality but possible role in violence traits. Am J Med Genet 105: 239–245
Zanarini MC, Frankenburg FR, Parachini EA (2004) A preliminary, randomized trial of fluoxetine, olanzapine, and the olanzapinefluoxetine combination in women with borderline personality disorder. J Clin Psychiatry 65: 903–907
Zetzsche T, Preuss UW, Frodl T et al. (2007) Hippocampal volume reduction and history of aggressive behaviour in patients with borderline personality disorder. Psychiatry Res 154: 157–170
Zill P, Buttner A, Eisenmenger W et al. (2004) Single nucleotide polymorphism and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene in suicide victims. Biol Psychiatry 56: 581–586
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Bogerts, B., Peter, E., Schiltz, K. (2011). Aggression, Gewalt, Amok, Stalking. In: Möller, HJ., Laux, G., Kapfhammer, HP. (eds) Psychiatrie, Psychosomatik, Psychotherapie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-03637-8_81
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