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Aspiration and Inhalation

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Forensic Histopathology

Abstract

While aspiration of objects and coarse material, ­including gastric contents, can often be diagnosed macroscopically, aspiration of liquids or finer foreign matter, including blood or dust, can often only be proved with microscopy. Aspiration is considered to be evidence of vitality when the aspirated material has reached the peripheral branches of the bronchial tree (small bronchi, pulmonary alveoli). In the case of terminal or agonal aspiration, the aspirated material can at deepest be found in the tracheal lumen and the main bronchi, as well as occasionally in the segmental bronchi. However, the spread of aspirated material to the periphery of the bronchial tree as a result of resuscitation measures must be considered when making a diagnosis. Histological examinations are particularly necessary to demonstrate aspiration as a sign of vitality, which is usually possible histologically but also radiologically prior to autopsy in more severe cases (Yen et al. 2005).

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Dettmeyer, R.B. (2011). Aspiration and Inhalation. In: Forensic Histopathology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-20659-7_11

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