Abstract
The aim of the study was to determine the prognostic value of a high augmentation index, which was a surrogate marker of arterial stiffness in patients with spontaneous intracerebral hemorrhage. The outcome was divided into two groups in which the following data were collected in a computer running SphygmoCor CvMS software version 8.2. Logistic regression analysis was carried out among significant variables to identify an independent predictor of 6-month outcome and mortality. Sixty patients were recruited into the study. Admission Glasgow Coma Scale score (OR, 0.7; 95% CI, 0.450–0.971; P = 0.035), total white cell count (OR, 1.2; 95% CI, 1.028–1.453; P = 0.023) and hematoma volume (OR, 1.1; 95% CI, 1.024–1.204; P = 0.011) were found to be statistically significant for identifying poor 6-month outcome in multivariate analysis.
Factors independently associated with mortality were a high augmentation index (OR, 8.6; 95% CI, 1.794–40.940; P = 0.007) and midline shift (OR, 7.5; 95% CI, 1.809–31.004; P = 0.005). Admission Glasgow Coma Scale score, total white cell count and hematoma volume were significant predictors for poor 6-month outcome, and a high augmentation index and midline shift were predictors for 6-month mortality in this study.
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Acknowledgments
Prof Jafri Malin Abdullah FASc, MD. PhD, FRCS (Ed), FACS, FICS (USA), FWFNS, DSCN (Belgium) Chairperson of Task Force of the Academy of Science Malaysia in improving Research and Development in Health and Medical Sciences
Conflict of interest statement We declare that we have no conflict of interest.
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Keong, L.H., Ghani, A.R.I., Awang, M.S., Sayuthi, S., Idris, B., Abdullah, J.M. (2011). The Role of a High Augmentation Index in Spontaneous Intracerebral Hemorrhage to Prognosticate Mortality. In: Zhang, J., Colohan, A. (eds) Intracerebral Hemorrhage Research. Acta Neurochirurgica Supplementum, vol 111. Springer, Vienna. https://doi.org/10.1007/978-3-7091-0693-8_63
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