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Giant Cell Tumor

Giant Cell Tumor of Bone, Osteoclastoma

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Book cover Bone and Soft Tissue Tumors

Abstract

Giant cell tumor of bone is defined as an intramedullary bone tumor, with a specific predilection for age and location, composed of mononucleated cells and osteoclast-like multi-nucleated giant cells, and having a variable and unpredictable potential for growth1. The giant cell tumor usually behaves as a benign tumor, but has a significant tendency to recur locally and, rarely, may produce pulmonary metastases. These have the same histological features as the primary tumor and are frequently curable. Rarely, a giant cell tumor may transform into a high-grade sarcoma.

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Giant cell tumor

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Authors and Affiliations

  1. University of Bologna, Italy

    Mario Campanacci M.D. (Orthopaedic Surgeon, Professor of Orthopaedic Surgery and Pathology, Director of the 1st Orthopaedic Clinic, Director of the Graduate School of Orthopaedics, Director of the Tumor Centre)

  2. Rizzoli Orthopaedic Institute, Bologna, Italy

    Mario Campanacci M.D. (Orthopaedic Surgeon, Professor of Orthopaedic Surgery and Pathology, Director of the 1st Orthopaedic Clinic, Director of the Graduate School of Orthopaedics, Director of the Tumor Centre)

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© 1999 Springer-Verlag Wien

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Campanacci, M. (1999). Giant Cell Tumor. In: Bone and Soft Tissue Tumors. Springer, Vienna. https://doi.org/10.1007/978-3-7091-3846-5_4

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  • DOI: https://doi.org/10.1007/978-3-7091-3846-5_4

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