Editors:
- Provides cutting-edge research developments on the regulation of cytokine expression
- Illustrates the regulation of cytokine expression in both healthy physiological conditions and in pathological situations
- Covers all major cytokines with respect to the regulation of their gene expression and protein production
- Written by experts in this field
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 941)
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Table of contents (10 chapters)
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Front Matter
About this book
This book explores the major cytokines, such as IL-1 and IFN-γ, with respect to the regulation of their gene expression and protein production in specific immune cell types. It discusses both healthy physiological settings and in pathological situations in which the expression of some cytokines could be dysregulated, resulting in either immunodeficiency or exacerbated inflammatory sequelae in animal models as well as in human patients. Cytokines are important regulators of immune responses that require the highly coordinated participation and communication of multiple cell types. The expression of cytokines by various producer cell types is therefore carefully regulated in response to environmental cues at multiple levels: transcription, translation and posttranslational modification. Presentingcutting-edge advances in our understanding of the regulation of cytokine expression, this book is a valuable resource for anyone involved or interested in immune regulation.
Editors and Affiliations
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State Key Laboratory of Microbial Metabolism, Sheng Yushou Center of Cell Biology and Immunology, School of Life Science and Biotechnology, Shanghai Jiaotong University, Shanghai, China
Xiaojing Ma
About the editor
Bibliographic Information
Book Title: Regulation of Cytokine Gene Expression in Immunity and Diseases
Editors: Xiaojing Ma
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-94-024-0921-5
Publisher: Springer Dordrecht
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature B.V. 2016
Hardcover ISBN: 978-94-024-0919-2Published: 21 October 2016
Softcover ISBN: 978-94-024-1436-3Published: 29 June 2018
eBook ISBN: 978-94-024-0921-5Published: 12 October 2016
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: VIII, 225
Number of Illustrations: 1 b/w illustrations, 22 illustrations in colour
Topics: Immunology, Gene Expression, Cytokines and Growth Factors, Cell Biology