Abstract
Intravitreal liposome-encapsulated antibiotics and antiviral drugs were used in patients with acute toxoplasmosis retinochoroiditis, presumed propionibacterium acne endophthalmitis after cataract surgery, and presumed cytomegalovirus retinitis associated with AIDS. A single intravitreal dose was effective in the treatment of all the conditions. Intravitreal liposomes may prove to be an advantageous drug delivery system for the treatment of chronic intraocular inflammatory disorders.
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Peyman, G.A., Charles, H.C., Liu, K.R. et al. Intravitreal liposome-encapsulated drugs: A preliminary human report. Int Ophthalmol 12, 175–182 (1988). https://doi.org/10.1007/BF00130002
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DOI: https://doi.org/10.1007/BF00130002