Abstract
Chronic endophthalmitis, due to Corynebacterium minutissimum, developed in a patient following uncomplicated extracapsular cataract extraction and posterior chamber intraocular lens (PC-IOL) implantation. In this case, which to our knowledge is the first reported case of Corynebacterium minutissimum endophthalmitis, chronic inflammation persisted for 8 months with fluctuations in the inflammation. The specimens from the capsular bag yielded positive culture, but the vitreous culture was negative. The case was successfully treated by a capsular bag irrigation with vancomycin.
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References
Fox GM, Joondeph BC, Flynn HW, Pflugfelder SC, Roussel TJ. Delayed-onset pseudophakic endophthalmitis. Am J Ophthalmol 1991; 11: 163–73.
Mandelbaum S, Meisler DM. Postoperative chronic microbial endophthalmitis. Int Ophthalmol Clin 1993; 33: 71–9.
Coyle MB, Hollis DG, Groman NB. Corynebacterium spp. and other coryneform organisms. In: Lennette EH, Balows A, Hausler WJ, Shadomy HJ (eds) ‘Manual of Clinical Microbiology’, 4th ed. American Society for Microbiology, Washington; D.C., pp 193–204, 1985.
Lipsky BA, Goldberger AC, Tompkins LS, et al. Infections caused by nondiphtheria corynebacteria. Rev Infect Dis 1982; 4: 1220–35.
Locksley RM. The lowly diphtheroid: non diphtheria corynebacterial infections in humans. West J Med 1982; 137: 45–52.
Rubinfeld RS, Cohen EJ, Arentsen JJ, Laibson PR. Diphtheroids as ocular pathogens. Am J Ophthalmol 1989; 108: 251–4.
Hanscom T, Maxwell WA. Corynebacterium endophthalmitis: Laboratory studies and report of a case treated by vitrectomy. Arch Ophthalmol 1979; 97: 500.
Margo CE, Pavan PR, Groden LR. Chronic vitritis with macrophagic inclusions. A sequela of treated endophthalmitis due to a coryneform bacterium. Ophthalmology 1988; 95: 156.
McManaway JW, Weinwerg RS, Coudron PE. Corynebacterium endophthalmitis. Two case reports. Arch Ophthalmol 1990; 108: 942–4.
Margo CE, Pavan PR, Groden LR. Chronic vitritis with macrophagic inclusions: a sequela of treated endophthalmitis due to a coryneform bacterium. Ophthalmology 1988; 95: 156–61.
Salvanet-Bouccara A, Serrhini A, Forestier F, Dublanchet A. Endophtalmie chronique a Corynebacterium. A propos de 3 cas. J Fr Ophthalmol 1992; 15: 378–83.
Riley PS, Hollis GB, Utter DG, Weaver RE, Baker CN. Characterization and identification of 95 diptheroid (group JK) cultures isolated from clinical specimens. J Clin Microbial 1979; 9: 418–24.
Krech T, Hollis DG. Corynebacterium and related organisms. In: Balows A, Hausler WJ, Herrmann KL, Isenberg HD, Shadomy HJ (eds) ‘Manual of Clinical Microbiology’, 5th ed. American Society for Microbiology, Washington, D.C., pp 277–286, 1991.
Owens SL, Lam S, Tessler HH, Deutsch TA. Preliminary study of a new intraocular method in the diagnosis and treatment of propionibacterium acnes endophthalmitis following cataract extraction. Ophthalmic Surg 1993; 108: 9442–4.
Brady SE, Cohen EJ, Fischer DH. Diagnosis and treatment of chronic postoperative bacterial endophthalmitis. Ophthalmic Surg 1988; 19: 580–4.
Meisler DM, Mandelbaum S. Propionibacterium - associated endophthalmitis after extracapsular cataract extraction. Review of reported cases. Ophthalmology 1989; 96: 54–61.
Chien AM, Raber IM, Fischer DH, Eagle RC, Naidoff MA. Propionibacterium acnes endophthalmitis after intracapsular cataract extraction. Ophthalmology 1992; 99: 487–90.
Zambrano W, Flynn HW, Pflugfelder SC, et al. Management options for propionibacterium acnes endophthalmitis. Ophthalmology 1989; 96: 1100.
Winward KE, Pflugfelder SC, Flynn HW, Roussel TJ, Davis JL. Postoperative propionibacterium endophthalmitis. Treatment strategies and long term results. Ophthalmology 1993; 100: 447–51.
Barza M. Antibacterial agents in the treatment of ocular infections. Infect Dis Clin North Am 1989; 3: 533–51.
Borhani H, Peyman GA, Wagapoor H. Use of vancomycin in vitrectomy infusion solution and evaluation of retinal toxicity. Int Ophthalmol 1993; 17: 85–8.
Wilhelm MP. Vancomycin. Mayo Clin Proc 1991; 66: 1165–70.
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Arsan, A.K., Sizmaz, S., Özkan, S.B. et al. Corynebacterium minutissimum endophthalmitis: Management with antibiotic irrigation of the capsular bag. Int Ophthalmol 19, 313–316 (1995). https://doi.org/10.1007/BF00130928
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DOI: https://doi.org/10.1007/BF00130928