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Fundus changes in chronic membranoproliferative glomerulonephritis type II

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Abstract

Chronic membranoproliferative glomerulonephritis type II (dense deposit disease) is a renal disease characterized by dense deposits in the glomerular and tubular basement membranes. We report a retinopathy with diffuse retinal pigment alterations in 11 out of 12 patients with this disease. Four of the eleven patients also presented disciform macular detachment and choroidal neovascularisation. The lesions were observed at the earliest 1 year after the diagnosis of the renal disease. In a control group of 17 patients with chronic membranoproliferative glomerulonephritis type I none of the patients presented similar fundus lesions.

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Authors and Affiliations

  1. Department of Ophthalmology, K.U. Leuven, Leuven, Belgium

    Brigitte Michielsen, Anita Leys MD & Luc Missotten

  2. Department of Pathology, K.U. Leuven, Leuven, Belgium

    Boudewijn Van Damme

Authors
  1. Brigitte Michielsen
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  2. Anita Leys MD
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  3. Boudewijn Van Damme
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  4. Luc Missotten
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Michielsen, B., Leys, A., Van Damme, B. et al. Fundus changes in chronic membranoproliferative glomerulonephritis type II. Doc Ophthalmol 76, 219–229 (1990). https://doi.org/10.1007/BF00142681

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  • DOI: https://doi.org/10.1007/BF00142681

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