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Massive pelvic osteolysis in the Gorham-Stout syndrome

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Summary

Massive osteolysis is a very rare tumour-like lesion usually affecting young adults. There are 132 reported cases which we have reviewed, including 31 single cases of pelvic involvement. The term “massive osteolysis” is based on the typical radiological findings, such as increasing translucency and loss of bone density. The diagnosis of the Gorham-Stout syndrome must be confirmed by the microscopic finding of intramedullary vascular structures. Our patient was a 23 year old white Caucasian, who had the full clinical signs of Gorham-Stout syndrome. She had achieved 2 normal pregnancies and deliveries in spite of her massive pelvic osteolysis.

Résumé

L'ostéolyse massive est une lésion pseudotumorale extrêmement rare, qui atteint habituellement les adultes jeunes. Il en existe 132 cas publiés, qui ont été passés en revue, parmi lesquels 31 cas d'atteinte limitée au bassin. Le terme «d'ostéolyse massive» est basé sur les images radiologiques typiques, telles que l'augmentation de la transparence et la diminution de la densité de l'os. Le diagnostic de syndrome de Gorham-Stout doit être étayé par des constatations microscopiques concernant les structures vasculaires intra-médullaires. Notre malade est une européenne blanche de 23 ans qui présente le tableau complet du syndrome de Gorham-Stout. Elle a eu deux grossesses et deux accouchements normaux malgrè son ostéolyse massive du bassin.

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Authors and Affiliations

  1. Orthopädische Abteilung der Universitätskliniken, Hugstetter Strasse 55, W-7800, Freiburg i. Brsg., Germany

    H.-A. Kulenkampff

  2. Abteilung Röntgendiagnostik der Radiologischen Universitätskliniken, W-7800, Freiburg i. Brsg., Germany

    G. M. Richter

  3. Abteilung Strahlentherapie und Radiologische Onkologie der Radiologischen Klinik der St Vincentius-Krankenhäuser, W-7500, Karlsruhe, Germany

    W. E. Hasse

  4. Referenzzentrum für Knochentumoren am Pathologischen Institut der Universität, W-7800, Freiburg i. Brsg., Germany

    C.-P. Adler

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  1. H.-A. Kulenkampff
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Kulenkampff, HA., Richter, G.M., Hasse, W.E. et al. Massive pelvic osteolysis in the Gorham-Stout syndrome. International Orthopaedics 14, 361–366 (1990). https://doi.org/10.1007/BF00182645

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