Abstract
In order to measure the effect of industry-independent information on the prescribing of benzodiazepines in general practice, 128 primary practitioners were randomly allocated to three intervention groups after stratification by year of graduation. One third of the participating physicians were forwarded written information about the indications and limitations of benzodiazepines, another third received both written and oral information, and the remaining third (the control group) obtained no information at all.
A comparison of the number of benzodiazepines prescribed per 100 patient contacts with prescription before and after the intervention showed an average decrease of 3% in the control group, of 14% in physicians who received only written information, and of 24% in physicians who were given additional oral information. Post hoc pairwise comparisons revealed a significant difference at the 1% level in the number of benzodiazepines prescribed between physicians who received both written and oral information and the control group.
A follow-up survey conducted 4 weeks after the intervention showed that the oral information campaign positively affected physicians' attitudes about the value of oral drug information from an industry-independent source.
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References
Schaffner W, Ray WA, Federspiel CF, et al (1983) Improving antibiotic prescribing in office practice: a controlled trial of three educational methods. JAMA 250: 1728–1732
Avorn J, Soumerai S (1983) Improving drug therapy decisions through educational outreach. A randomized controlled trial of academically based ‘detailing’. N Engl J Med 308: 1457–1463
Avorn J, Soumerai S, Taylor W, et al (1988) Reduction of incorrect antibiotic dosing through a structured educational form. Arch Int Med 148: 1720–1724
Harvey K, et al (1986) Educational antibiotic advertising. Med J Aust 145: 28–32
Ray WA, Blaser DG, et al (1986) Reducing long term diazepam prescribing in office practice. A controlled trial of educational visits. JAMA 256: 2536–2539
Catalan J, Gath DH (1985) Benzodiazepines in general practice: time for a decision. BMJ 290: 1374–1376
Drury VWM (1985) Benzodiazepines — a challenge to rational presribing. J R Coll Gen Pract 35: 86–88
Ashton H (1989) Risks of dependence on benzodiazepine drugs: a major problem of long term treatment. BMJ 298: 103–104
The APA task force report on benzodiazepine dependence, toxicity, and abuse. (1991) Am J Psychiatry 148 (2): 151–152
Health and Medical Research Council (1991) Guidelines for the prevention and management of benzodiazepine dependence. Monograph Series No 3, Canberra
Russell J, Lader M (1992) Guidelines for the prevention and treatment of benzodiazepine dependence. Mental Health Foundation, London
NHG-standaard Slapeloosheid en Slaapmiddelen (1992) Huisarts en wetenschap 35: 212–219
Balter MB, Manheimer DI, Mellinger GD, Uhlenhuth EH (1984) A cross-national comparison of anti-anxiety/sedative drug use. Curr Med Res Opin 8 [Suppl 4]: 5–20
Cannoodt L (1987) Informatieverwerving en andere determinanten van het voorschrijfgedrag van huisartsen in Vlaanderen. [Information processing and other determinants of the prescribing behaviour of general practitioners in Flanders] Gezondheid Samenleving 8: 231–240
Salinsky JV, Doré CJ (1987) Characteristics of long term benzodiazepine users in general practice. J Roy Coll Gen Pract 37: 202–204
Holm M (1988) Prescription of benzodiazepines in general practice in the County of Arhus, Denmark. Dan Med Bull 35: 495–499
Nolan L, O'Malley K (1988) Patients, prescribing, and benzodiazepines. Eur J Clin Pharmacol 35: 225–229
Simpson RJ, Power KG, Wallace LA, et al (1990) Controlled comparison of the characteristics of long-term benzodiazepine users in general practice. Br J Gen Pract 40: 22–26
Nicholas D, Hammond SM (1991) Personality characteristics of long-term benzodiazepine users. Person Individ Diff 13: 221–223
Lagro-Janssen ALM, Liberton IJW (1993) Profielen van regelmatige gebruikers van benzodiazepinen in een huisartspraktijk. [Profiles of regular users of benzodiazepines in a primary practice] Ned Tijdschr Geneeskd 137: 1969–1972
Hemminki E (1975) Review of literature on the factors affecting drug prescribing. Soc Sci Med 11: 115
Soumerai SB, Avorn J (1990) Principles of educational outreach (‘academic detailing’) to improve clinical decision making. JAMA 263: 549–556
Ray WA, et al (1985) Persistence of improvement in antibiotic prescribing in office practice. JAMA 253: 1774–1776
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Berings, D., Blondeel, L. & Habraken, H. The effect of industry-independent drug information on the prescribing of benzodiazepines in general practice. Eur J Clin Pharmacol 46, 501–505 (1994). https://doi.org/10.1007/BF00196105
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DOI: https://doi.org/10.1007/BF00196105