Summary
A family with a distinct form of congenital generalized hypertrichosis was studied. Males were more severely affected than females, who exhibited asymmetric hair distribution. This finding was attributed to lyonization, since genealogical studies indicated an X-linked pattern of inheritance. A back mutation is postulated as the origin of this new phenotype.
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Macías-Flores, M.A., García-Cruz, D., Rivera, H. et al. A new form of hypertrichosis inherited as an X-linked dominant trait. Hum Genet 66, 66–70 (1984). https://doi.org/10.1007/BF00275189
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DOI: https://doi.org/10.1007/BF00275189