Skip to main content
Log in

Water and electrolyte balance after ileal J pouch-anal anastomosis in ulcerative colitis and familial adenomatous polyposis

  • Original Articles
  • Published:
International Journal of Colorectal Disease Aims and scope Submit manuscript

Abstract

The water and electrolyte balance was studied in 31 patients with ulcerative colitis (UC) and 22 with familial adenomatous polyposis (FAP) who underwent staged surgery involving colectomy and ileal J pouch-anal anastomosis (IAA), preoperatively, after terminal ileostomy, after high ileostomy, and after ileostomy closure. Serum electrolytes did not differ between each surgical stage. After terminal or high ileostomy, daily urine volume and urinary sodium loss was significantly lower, and daily fecal weight and fecal sodium loss was significantly higher than preoperatively. After ileostomy closure, urinary and fecal sodium loss became closer to preoperative value. Daily urinary potassium loss was significantly higher and fecal loss was lower after terminal and high ileostomy than preoperatively and did not show a significant change after ileostomy closure. The urinary sodium to potassium ratio after ileostomy closure was lower than preoperatively, but was higher than that after terminal and high ileostomy. Plasma aldosterone and renin levels were only significantly increased after high ileostomy. These findings indicate that high or terminal ileostomy caused chronic dehydration, which was compensated for by activation of the renin-aldosterone axis, while the water and electrolyte balance became closer to normal after ileostomy closure following ileoanal anastomosis.

Résumé

Un bilan hydro-électrolytique a été établi chez 31 patients porteurs d'une recto-colite ulcéro-hémorragique et 22 porteurs d'une polypose familiale; tous avaient subi plusieurs temps chirurgicaux comprenant une colectomie et la confection d'une anastomose iléoanale avec une pochen en J. Les dosages ont été réalisés à 4 péeriodes au cours du suivi chirurgical, en particulier en préopératoire, après la colectomie avec confection d'une iléostomie terminale, après l'anastomose iléo-anale sous couvert d'une iléostomie de protection et après fermeture de l'iléostomie de protection. Les taux sériques d'électrolytes ne diffèrent pas entre les 4 périodes chirurgicales. Après iléostomie terminale ou après iléostomie de protection, le volume urinaire quotidien et les pertes de sodium urinaire étaient significativement plus basses alors que le poids fécal quotidien et les pertes de sodium fécales étaient significativement plus élevées qu'en préopératoire. Après fermeture de l'iléostomie, les valeurs d'excrétion du sodium urinaire et fécal étaient voisines à celles de la valeur pré-opératoire. L'élimination journalière de potassium par les urinaires était plus élevée et les pertes fécales plus basses après iléostomie terminale et iléostomie de protection que celles observées en préopératoire; ces valeurs ne changeaient pas de manière significative après fermeture de l'iléostomie. Le rapport sodium/potassium urinaire après fermeture de l'iléostomie est abaissé par rapport à la valeur pré-opératoire mais demeure plus élevé qu'après iléostomie terminale et iléostomie de protection. Le taux d'aldostérone et le taux de rénine plasmatique étaient significativement augmentés après une iléostomie de protection. Ces données tendent à démontrer qu'une iléostomie terminale ou une iléostomie de protection favorisent une déshydratation chronique avec une perte sodique compensée par l'activation du mécanisme rénine-aldostérone.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Phillips SF, Giller J (1973) The contribution of the colon to electrolyte and water conservation in man. J Lab Clin Med 81:733–746

    Google Scholar 

  2. Utsunomiya J, Yamamura T, Kusunoki M, Iwama T (1988) The current technique of ileoanal anastomosis. Dig Surg 5:207–214

    Google Scholar 

  3. Utsunomiya J, Iwama T, Imajo M, Matsuo, Sawai S, Yaegashi K, Hirayama R (1980) Total colectomy, mucosal proctectomy, and ileoanal anastomosis. Dis Colon Rectum 23: 459–466

    Google Scholar 

  4. Pemberton JH, Kelly KA, Beart RW, Dozois RR, Wolff BG, Ilstrup DM (1987) Ileal pouch-anal anastomosis for chronic ulcerative colitis. Long-term results. Ann Surg 206:504–5143

    Google Scholar 

  5. Shoji Y, Kusunoki M, Fujita S, Yamamura T, Utsunomiya J (1992) Functional role of the preserved rectal cuff in ileoanal anastomosis. Surgery 111:266–273

    Google Scholar 

  6. Silva HJ, Angelis CP, Soper N, Kettlewell MGW, Mortensen NJMcC, Jewell DP (1991) Clinical and functional outcome after restorative proctocolectomy. Br J Surg 78:1039–1044

    Google Scholar 

  7. Max E, Trabanino G, Peznick RK, Bailey HR, Smith KW (1987) Metabolic changes during the defunctionalized stage after ileal pouch-anal anastomosis. Dis Colon Rectum 30:508–512

    Google Scholar 

  8. Natori H, Utsunomiya J, Yamamura T, Benno Y, Uchida K (1992) Fecal and stomal bile acid composition after ileostomy or ileoanal anastomosis in patients with chronic ulcerative colitis and adenomatosis coli. Gastroenterology 102:1278–1288

    Google Scholar 

  9. Sakanoue Y, Kusunoki M, Shoji Y, Yanagi H, Yamamura T, Utsunomiya J (1992) Transitory elevation of serum amylase levels after restorative proctocolectomy. Int J Colorect Dis 7:210–213

    Google Scholar 

  10. Santavirta J, Harmoinen M, Karvonen AL, Matikainen M (1991) Water and electrolyte balance after ileoanal anastomosis. Dis Colon Rectum 34:115–118

    Google Scholar 

  11. Kusunoki M, Yamamura T, Ichii S, Fujita S, Nakai T, Utsunomiya J (1988) The effects of sodium valporate on plasma somatostatin and insulin in humans. J Clin Endocrinol Metab 67:1060–1063

    Google Scholar 

  12. Cooper JC, Williams NS, King RFGJ, Barker MCJ (1986) Effects of a long-acting somatostatin analogue in patients with severe ileostomy diarrhoea. Br J Surg 73:128–131

    Google Scholar 

  13. Kennedy HJ, Al-Dujaili EAS, Edwards CRW, Truelove SC (1983) Water and electrolyte balance in subjects with a permanent ileostomy. Gut 24:702–705

    Google Scholar 

  14. Brevinge H, Bosaeus I, Philipson BM, Kewenter J (1992) Sodium and potassium excretion before and after conversion from conventional to reservoir ileostomy. Int J Colorect Dis 7: 148–154

    Google Scholar 

  15. Imajo M (1981) Study of the small bowel transit time and physiochemical characteristics of the ileal excreta in abdominal and anal ileostomy (in Japanese with English Abstract) J Jpn Surg Soc 82:549–565

    Google Scholar 

  16. Kelly DG, Branon ME, Phillips SF, Kelly KA (1980) Diarrhoea after continent ileostomy Gut 21:711–716

    Google Scholar 

  17. Hill GL (1982) Metabolic complications of ileostomy. Clin Gastroenterol 11:260–267

    Google Scholar 

  18. Kusuhara K, Kusunoki M, Okamoto T, Sakanoue Y, Utsunomiya J (1992) Reduction of the effluent volume in high-output ileostomy patients by a somatostatin analogue, SMS 201-995. Int J Colorect 7:202–205

    Google Scholar 

  19. Hasner E (1965) Electrolyte excretion in the urine, saliva, and ileostomy fluid after administration of cortisol and cortisone and postoperatively. Acta Chir Scand Suppl 343:147–153

    Google Scholar 

  20. Hill GL, Mair WSJ, Goligher JC (1975) Cause and management of high volume output salt-depleting ileostomy. Br J Surg 62: 720–726

    Google Scholar 

  21. Clarke AM, Hill GL, Macbeth WAAG (1967) Intestinal adaptation to salt depletion in a patient with an ileostomy. Gastroenterology 53:444–449

    Google Scholar 

  22. Hill GL, Mair WSJ, Goligher JC (1974) Impairment of “ileostomy adaptation” in patients after ileal resection. Gut 15: 982–987

    Google Scholar 

  23. Delin K, Fasth S, Andersson H, Aurell M, Huluten L, Jagenburg R (1984) Factors regulating sodium balance in proctocolectomized patients with various ileal resections. Scand J Gastroenterol 19:145–149

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Okamoto, T., Kusunoki, M., Kusuhara, K. et al. Water and electrolyte balance after ileal J pouch-anal anastomosis in ulcerative colitis and familial adenomatous polyposis. Int J Colorect Dis 10, 33–38 (1995). https://doi.org/10.1007/BF00337584

Download citation

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00337584

Keywords

Navigation