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Experimentell-psychologische Differenzierung der Wirkung von zwei Psychostimulantien am Menschen (F-1983 und Amphetamin)

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Summary

A method which makes possible a quantitative assessment of fatigue after one sleepless night and the study of it's neutralisation by two different drugs is described. By means of combining psychological stress and relaxation and graduated motor stress in the performance-test a qualitative difference between the stimulating effect of Amphetamine and the new drug F-1983 is demonstrated:

18 students were given 10 mg Amphetamin, 60 mg F-1983 or Placebo in a double-blind study. In the short period of stress with an essential motor factor of performance, Amphetamine produced inferior results than F-1983 (and even Placebo). During the period of relaxation with less motor activity, both drugs had a similar stimulating effect in comparison to Placebo. The described difference between these two drugs is related to a more important activation of motor function produced by Amphetamine in contrast to F-1983.

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Authors and Affiliations

  1. Centre de recherche psychopathologique, Clinique psychiatrique universitaire de Lausanne, Schweiz

    H. Heimann & G. Lukàcs

Authors
  1. H. Heimann
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  2. G. Lukàcs
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Heimann, H., Lukàcs, G. Experimentell-psychologische Differenzierung der Wirkung von zwei Psychostimulantien am Menschen (F-1983 und Amphetamin). Psychopharmacologia 8, 79–90 (1965). https://doi.org/10.1007/BF00404168

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  • DOI: https://doi.org/10.1007/BF00404168

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