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The use of two measures of health-related quality of life in HIV-infected individuals: a cross-sectional comparison

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Abstract

Two measures of health-related quality of life in 65 HIV-infected individuals were compared in a cross-sectional design. The Quality of Well-Being Scale (QWB) results in a single score ranging from death to perfect health. The MOS-HIV Health Survey (MOS-HIV, 34-item version) gives scores in 11 dimensions. The QWB score distinguished subjects with AIDS from those who were asymptomatic (p=0.027). For the seven multi-item scales of the MOS-HIV, Cronbach's alpha ranged from 0.85–0.95, indicating good internal consistency reliability. Clinical HIV-infection status was significantly associated with the dimensions of Overall Health (p=0.002), Role Function (p=0.022), Social Function (p=0.037), Energy/Fatigue (p=0.027) and Health Distress (p=0.025). All eleven dimensions of the MOS-HIV were significantly correlated with the QWB score (Spearman's coefficient = 0.405–0.670; for all, p<0.01) and the QWB score could be predicted from the MOS-HIV dimension scores using multiple regression. The QWB and the MOS-HIV may be useful in assessing health-related quality of life in patients infected with HIV.

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Authors and Affiliations

  1. Tucson Veterans Affairs Medical Center, Tucson, USA

    A. E. Copfer, N. M. Ampel, C. L. Dols & K. Colgan

  2. University of Arizona College of Medicine, Tucson, USA

    S. J. Coons

  3. University of Arizona College of Pharmacy, Tucson, USA

    T. E. Hughes & K. J. Gregor

  4. the Johns Hopkins University School of Hygiene and Public Health, Baltimore, USA

    A. W. Wu

Authors
  1. A. E. Copfer
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  2. N. M. Ampel
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  3. T. E. Hughes
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  4. K. J. Gregor
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  5. C. L. Dols
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  6. S. J. Coons
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  7. K. Colgan
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  8. A. W. Wu
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Additional information

Funding support for this study provided by the Center for Pharmaceutical Economics of the University of Arizona.

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Copfer, A.E., Ampel, N.M., Hughes, T.E. et al. The use of two measures of health-related quality of life in HIV-infected individuals: a cross-sectional comparison. Qual Life Res 5, 281–286 (1996). https://doi.org/10.1007/BF00434750

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  • DOI: https://doi.org/10.1007/BF00434750

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