Abstract
Blood volume was studied in 160 infants and children aged from one hour to 14 years. From these data linear and logarithmic regression equations relating blood volume to weight, height and surface area were calculated. Equations utilizing combined height and logarithmic weight values were found to be the most accurate for predicting blood volume. Therefore, nomograms were constructed for reading blood volume directly from height and weight.
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Betke, K.: Hämatologie der ersten Lebenszeit. Ergebn. inn. Med. Kinderheilk. N.F. 9, 437–509 (1958)
Betke, K., Kleihauer, E., Peter, H., Poser, G., Schlicht, I.: Rote Blutwerte bei gesunden Kindern aus Familien und aus Heimen. Dtsch. med. Wschr. 25, 1197–1203 (1964)
Bratteby, L.-E.: Studies on erythro-kinetics in infancy VIII. Mixing, disappearance rates and distribution volume of labelled erythrocytes and plasma proteins in early infancy. Acta Soc. Med. Upsal. 72, 249–271 (1967)
Bratteby, L.-E.: Studies on erythro-kinetics in infancy XI. The changes in circulating red cell volume during the first five months of life. Acta Paediat. Scand. 57, 215–224 (1968)
Brines, J. K., Gibson, J. G., Kunkel, P.: The blood volume in normal infants and children. J. Pediat. 18, 447–457 (1941)
Burmeister, W.: Body cell mass as the basis of allometric growth functions. Ann. Paediat. 204, 65–72 (1965)
Chaplin, H., Mollison, P. L., Vetter, H.: The body/venous hematocrit ratio: its constancy over a wide range. J. Clin. Invest. 32, 1309–1316 (1953)
Cropp, G. J. A.: Changes in blood and plasma volumes during growth. J. Pediat. 78, 220–229 (1971)
Darrow, D. C., Soule, H. C., Buckman, T. E.: Blood volume in normal infants and children. J. Clin. Invest. 5, 243–258 (1928)
Gorten, R. J.: The use of iodine-125 for precordial counting. J. Nucl. Med. 6, 169–174 (1965)
Gross, S., Godel, J. C.: Comparative studies of height and weight as a blood volume reference standard in normal children and children with sickle cell anemia. Amer. J. Clin. Path. 55, 662–670 (1971)
Karlberg, P., Lind, J.: Studies of the total amount of hemoglobin and the blood volume in children 1. Determination of total hemoglobin and blood volume in normal children. Acta Paediat. Scand. 44, 17–34 (1955)
Linderkamp, O., Butenandt, I., Euringer, A., Riegel, K.: Blutvolumen und Albuminschwund verbrannter Kinder. In: VI. Symposion über Pädiatrische Intensivmedizin (ed. P. Emmrich), pp. 281–284. Stuttgart: Thieme 1977
Linderkamp, O., Holthausen, H., Seifert, J., Butenandt, I., Riegel, K. P.: Accuracy of blood volume estimations in critically ill children using 125I-labeled albumin and 51Cr-labeled red cells. Europ. J. Pediat. 125, 143–151 (1977)
Linderkamp, O., Höpner, F., Klose, H., Riegel, K., Hecker, W. C.: Solitary hepatic hemangioma in a newborn infant complicated by cardiac failure, consumption coagulopathy, microangiopathic hemolytic anemia, and obstructive jaundice. Case report and review of the literature. Europ. J. Pediat. 124, 23–29 (1976)
Linderkamp, O., Mader, T., Butenandt, O., Riegel, K. P.: Plasma volume estimation in severely ill infants and children using a simplified Evans blue method. Europ. J. Pediat. 125, 135–141 (1977)
Linderkamp, O., Roth, G., Sengespeik, C., Versmold, H., Riegel, K.: Blutvolumen, Serumeisen und Erythrozytenparameter von ausgetragenen, früh abgenabelten Säuglingen im ersten Lebensjahr. Klin. Pädiat. 186, 511–518 (1974)
McIntosh, R.: The determination of the circulating blood volume in infants by the carbon monoxide method. J. Clin. Invest. 7, 203–227 (1929)
Morse, M., Cassels, D. E., Schlutz, F. W.: Blood volumes of normal infants. Amer. J. Physiol. 151, 448–458 (1947)
Prader, A., Rossi, E., Wodenegg, M.: Blutuntersuchungen beim Morbus caeruleus I. Plasmaund Blutvolumen. Helv. Paediat. Acta 4, 267–273 (1949)
Retzlaff, J. A., Tauxe, W. N., Kiely, J. M., Stroebel, C. F.: Erythrocyte volume, plasma volume and lean body mass in adult men and women. Blood 33, 649–661 (1968)
Russell, S. J. M.: Blood volume studies in healthy children. Arch. Dis. Childh. 24, 88–98 (1949)
Sachs, L.: Angewandte Statistik. Berlin-Heidelberg-New York: Springer 1974
Sendroy, J., Cecchini, L. P.: Determination of human body surface area from height and weight. J. Appl. Physiol. 7, 1–12 (1954)
Shah, P. M.: Blood volume studies in edematous children. I. Normal children. Indian J. med. Sci. 15, 109–116 (1961)
Sisson, T. R. C., Lund, C. J., Whalen, L. E., Telek, A.: The blood volume of infants. I. The full-term infant in the first year of life. J. Pediat. 55, 163–179 (1959)
Sukarochana, K., Parenzan, L., Thakurdas, N., Kiesewetter, W. B.: Red cell mass determinations in infancy and childhood, with the use of radioactive chromium. J. Pediat. 59, 903–908 (1961)
Wolner, E., Domanig, E., Elkadi, A., Helmer, F., Römer, P.: Über eine einfache Beziehung zwischen Blutvolumen und Köperoberfläche. Z. Kreislaufforsch. 57, 79–84 (1968)
Yao, A. C., Lind, J.: Placental transfusion. Amer. J. Dis. Child. 127, 128–141 (1974)
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Linderkamp, O., Versmold, H.T., Riegel, K.P. et al. Estimation and prediction of blood volume in infants and children. Eur J Pediatr 125, 227–234 (1977). https://doi.org/10.1007/BF00493567
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DOI: https://doi.org/10.1007/BF00493567