Abstract
Recurrent parotid gland enlargement is a common disorder in children, while that of auto-immune aetiology is rare. Three children with recurrent parotid swelling had autoantibodies including antinuclear antibody, anti-SS-A (Sjögren syndrome-A), SS-B (Sjögren syndrome-B) antibodies and rheumatoid factor, abnormal sialograms and lymphocytic infiltration of salivary glands, which were consistent with Sjögren syndrome. Initially, all three lacked symptoms of keratocon-junctivitis sicca. During follow up, two patients developed xerostomia and were diagnosed as having primary Sjögren syndrome. Recurrent parotid enlargement appears to be important as an initial manifestation of Sjögren syndrome in children.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Abbreviations
- ANA:
-
anti nuclear antibody
- ESR:
-
erythrocyte sedimentation rate
- LE test:
-
lupus erythematosus test
- RNP:
-
ribonucleoprotein
- SS-A:
-
Sjögren syndrome-A
- SS-B:
-
Sjögren syndrome-B
References
Anderson DC (1982) Sjögren syndrome in the young: report of a case. J Oral Med 37:21–22
Celeda A, Beck D, Chavaz P, Kapanci Y, Cruchaud A (1980) Hypergammaglobulinemic purpura and Sjögren syndrome. Helv Paediatr Acta 35:569–576
Cudwin DS, Daniels TE, Wara DW, Ammann AJ, Barrett DJ, Whicher JP, Cowan MJ (1981) Spectrum of Sjögren syndrome in children. J Pediatr 98:213–217
Eliachar E, Perelman R, Hambourg M, Levasseur C, Marie J (1966) Syndrome de type “Geugert-Sjögren” chez un enfant. Ann Pediatr (Paris) 13:184–186
Fox IR, Howell FV, Bone RC, Michelson P (1984) Primary Sjögren syndrome: clinical and immunopathological feature. Semin Arthritis Rheum 14:77–105
Fox RI, Robinson CA, Curd JG, Kojin F, Howell F (1986) Sjögren syndrome: proposed criteria for classification. Arthritis Rheum 29:577–585
Franklin DJ, Smith RJH, Person MD, Pflugelder SC (1986) Sjögren syndrome in children. Otolaryngol Head Neck Surg 94:230–235
Ipp MM, Howard NJ, Tervo RC, Gelfand EW (1976) Sicca syndrome and total lipodystrophy: case in a fifteen-year-old female patient. Ann Intern Med 85:443–446
Jay MS, Freeman D, Jamieson D (1986) Sjögren syndrome in an adolescent. J Adolesc Health Care 7:53–56
Simila A, Kokkonen J, Kaski M (1978) Achalasia sicca-Juvenile Sjögren's syndrome with achalasia and gastric hyposecretion. Eur J Pediatr 129:175–181
Sjögren HS (1933) Zur Kenntnis der Keratoconjunctivitis Sicca. Acta Ophthalmol 11:1–151
Vermylen C, Meurant A, Noel H, Claus D, Cornu G (1985) Sjögren syndrome in a child. Eur J Pediatr 144:266–269
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Mizuno, Y., Hara, T., Hatae, K. et al. Recurrent parotid gland enlargement as an initial manifestation of Sjögren syndrome in children. Eur J Pediatr 148, 414–416 (1989). https://doi.org/10.1007/BF00595900
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00595900