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X-linked congenital retinoschisis

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Abstract

The natural history and electrophysiological findings of 52 patients with X-linked congenital retinoschisis with a follow-up of up to 26 years are described. The mean visual acuity was reduced to 0.24±0.2 and remained unchanged in most patients during this time. If visual loss occurred, it usually happened in the first decennium. The complications were retinal detachments in 11% and vitreous hemorrhages in 4% of the eyes. In general, the vitreous hemorrhages resolved spontaneously. Retinal detachments were treated successfully with conventional buckling procedures. Redetachments occurred in about 40%. Prophylactic laser coagulation was of no use because it was complicated by detachment in 43% of our series. The electro-oculogram was usually normal. In addition to the known electroretinographic findings of normal a-wave and reduced b-wave amplitudes, we found prolonged b-wave latencies and implicit times, as well as a reduced 30 Hz flicker response.

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Kellner, U., Brümmer, S., Foerster, M.H. et al. X-linked congenital retinoschisis. Graefe's Arch Clin Exp Ophthalmol 228, 432–437 (1990). https://doi.org/10.1007/BF00927256

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  • DOI: https://doi.org/10.1007/BF00927256

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