Skip to main content
Log in

Cricopharyngeal function and dysfunction

  • Published:
Dysphagia Aims and scope Submit manuscript

Abstract

The cricopharyngeus is a narrow band of muscle strategically placed between the pharynx and esophagus. Its normal function is vital to the efficient transfer of foodstuffs to the esophagus. Cine- and video-radiography are the major methods of studying the pharyngo-esophageal segment. More recently, refinements in manometric methods have complemented radiology, and have enabled us to achieve a better understanding of cricopharyngeal function in health and disease. Such an understanding of the physical forces necessary for normal bolus transfer, and the recognition of abnormal patterns of pharyngeal and cricopharyngeal motility, will hopefully lead us to a more rational approach to therapy in patients with pharyngeal dysphagia.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Kahrilas PJ, Dodds WJ, Dent J, Logemann JA, Shaker R: Upper esophageal sphincter function during deglutition.Gastroenterology 95:52–62, 1988

    Google Scholar 

  2. Jacob P, Kahrilas PJ, Herzon G, McLaughlin HB: Determinants of upper esophageal sphincter pressure in dogs.Am J Physiol 259:G245-G251, 1990

    Google Scholar 

  3. Cook U, Dent J, Collins SM: Upper esophageal sphincter tone and reactivity to stress in patients with a history of globus sensation.Dig Dis Sci 34:672–676, 1989

    Google Scholar 

  4. Lang IM, Dantas RO, Cook U, Dodds WJ: Videoradiographic, manometric, and electromyographic analysis of canine upper esophageal sphincter.Am J Physiol 260:G911-G919, 1991

    Google Scholar 

  5. Cook IJ, Dodds WJ, Dantas RO, Massey B, Kern MK, Lang JM, Brasseur JG, Hogan WJ: Opening mechanisms of the human upper esophageal sphincter.Am J Physiol 257:G748-G759, 1989

    Google Scholar 

  6. Asoh R, Goyal RK: Manometry and electromyography of the upper esophageal sphincter in the opossum.Gastroenterology 75:514–520, 1978

    Google Scholar 

  7. Jacob P, Kahrilas PJ, Logemann JA, Shah V, Ha T: Upper esophageal sphincter opening and modulation during swallowing.Gastroenterology 97:1469–1478, 1989

    Google Scholar 

  8. Shaw DW, Cook IJ, Dent J, Simula ME, Panagopoulos V, Gabb M, Shearman DJ: Age influences orophaymgeal and upper esophageal sphincter function during swallowing.Gastroenterology 98:A390, 1990

    Google Scholar 

  9. Dantas RO, Kern MK, Massey BT, Dodds WJ, Kahrilas PJ, Brasseur JG, Cook IJ, Lang IM: Effect of swallowed bolus variables on oral and pharyngeal phases of swallowing.Am J Physiol 258:G675-G681, 1990

    Google Scholar 

  10. Johnsson F, Shaw D, Gabb M, Cook IJ: Does body posture or gravity influence oropharyngeal and upper esophageal sphincter function during swallowing?Gastroenterology 102:A464, 1992

    Google Scholar 

  11. Miller AJ: Deglutition.Physiol Rev 62:129–184, 1982

    Google Scholar 

  12. Knauer CM, Castell JA, Dalton CB, Nowak L, Castell DO: Pharyngeal/upper esophageal sphincter pressure dynamics in humans.Dig Dis Sci 35(6):774–780, 1990

    Google Scholar 

  13. Mansson I, Sandberg N: Effects of surface anaesthesia on deglutition in man.Laryngoscope 84:427–437, 1974

    Google Scholar 

  14. Edwards DAW: Discriminatory value of symptoms in the differential diagnosis of dysphagia.Clin Gastroenterol 5:49–57, 1976

    Google Scholar 

  15. Ott DJ: Radiographic techniques and efficacy in evaluating esophageal dysphagia.Dysphagia 5:192–203, 1990

    Google Scholar 

  16. Dodds WJ, Logemann JA, Stewart ET: Radiologic assessment of abnormal oral and pharyngeal phases of swallowing.AJR 154:965–974, 1990

    Google Scholar 

  17. Jones B, Donner MW: Examination of the patient with dysphagia.Radiology 167:319–326, 1985

    Google Scholar 

  18. Siebert TL, Stein J, Poppel MH: Variations in the roentgen appearances of the “esophageal lips.”Am J Roentgenol 81:570–575, 1959

    Google Scholar 

  19. Seaman WB: Cineroentgenographic observations of the cricopharyngeus.Am J Roentgenol 96:922–931, 1966

    Google Scholar 

  20. Curtis DJ, Cruess DF, Bert T: The cricopharyngeal muscle: a videorecording review.AJR 142:497–500, 1984

    Google Scholar 

  21. Ekberg O, Nylander G: Cineradiography of the pharyngeal stage of deglutition in 150 individuals without dysphagia.Br J Radiol 55:253–257, 1982

    Google Scholar 

  22. Dantas RO, Cook U, Dodds WJ, Kern MK, Lang IM, Brasseur JG: Biomechanics of cricopharyngeal bars.Gastroenterology 99:1269–1274, 1990

    Google Scholar 

  23. Cruse JP, Edwards DAW, Smith JF, Wylie JH: The pathology of cricopharyngeal dysphagia.Histopathology 3:223–232, 1979

    Google Scholar 

  24. Zenker FA, Ziemssen H Von: Dilatations of the esophagus. In:Cyclopaedia of the Practice of Medicine, vol. III. London: Low, Maston, Searle & Rivington, 1878, pp 46–68

    Google Scholar 

  25. Cook IJ, Gabb M, Panagopoulos V, Jamiesson GG, Dodds WJ, Dent J, Shearman DJ: Pharyngeal (Zenker's) diverticulum is a disorder of upper esophageal sphincter opening.Gastroenterology 103:1229–1235, 1992

    Google Scholar 

  26. Lichter I: Motor disorder in pharyngoesophageal pouch.J Thorac Cardiovasc Surg 76:272–275, 1978

    Google Scholar 

  27. Cook IJ, Blumbergs P, Cash K, Jamieson GG, Shearman DJ: Structural abnormalities of the cricopharyngeus muscle in patients with pharyngeal (Zenker's) diverticulum.J Gastroenterol Kepatol 7:556–562, 1992

    Google Scholar 

  28. Hurwitz AL, Nelson JA, Haddad JK: Oropharyngeal dysphagia: manometric and cine-esophagraphic findings.Am J Dig Dis 20:313–318, 1975

    Google Scholar 

  29. Ekberg O, Nylander G: Pharyngal dysfunction after treatment for pharyngeal cancer with radiotherapy.Gastrointest Radiol 8:97–104, 1983

    Google Scholar 

  30. Donner M, Silbiger M: Cinefluorographic analysis of pharyngeal swallowing in neuromuscular disorders.Am J Med Sci 251:600–616, 1966

    Google Scholar 

  31. Jones B, Ravich WJ, Donner MW, Kramer SS, Hendrix TR: Pharyngoesophageai interrelationships: observations and working concepts.Gastrointest Radiol 10:225–233, 1988

    Google Scholar 

  32. Margulies SI, Brunt PW, Donner MW, Silbiger ML: Familial dysautonomia: a cineradiographic study of swallowing mechanisms.Radiology 90:107–116, 1968

    Google Scholar 

  33. Calne DB, Shaw DG, Spiers ASD: Swallowing in parkinsonism.Br J Radiol 43:456–1157, 1970

    Google Scholar 

  34. Castell JA, Castell DO, Duranceau A: Pharyngeal and upper esophageal sphincter manometric characteristics of patients with oculopharyngeal muscular dystrophy.Gastroenterology 100(5):A39, 1991

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cook, I.J. Cricopharyngeal function and dysfunction. Dysphagia 8, 244–251 (1993). https://doi.org/10.1007/BF01354546

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01354546

Key words

Navigation