Summary
One hundred and three ever-married women with newly diagnosed Chronic Obstructive Pulmonary Disease (COPD), who have never smoked, and 179 ever-married women who were visiting friends or relatives at the same hospital during the same period and have never smoked, were interviewed regarding the smoking habits of their husbands. There was statistically marginally significant difference between the COPD cases and the controls with respect to their husband's smoking habits. The association was irregular with respect to daily number of cigarettes smoked but there was a smooth dose response curve with respect to life long total number of cigarettes smoked, with women whose husband smoked more that 300 thousand cigarettes having a relative risk of 1.8 (90% confidence interval of 0.9–3.6) compared to women whose husband has never smoked. These findings, and converging related evidence, indicate that exposure to environmental tobacco smoke may be a risk factor for the development of COPD.
Résumé
Cent-trois femmes, mariées de longue date, n'ayant jamais fumé, et chez qui un syndrome broncho-obstructif chronique (SOC) a été récemment diagnostiqué, ont été interrogées pour ce qui concerne les habitudes tabagiques de leur maris. Leurs réponses furent comparées à celles de 179 femmes, également mariées de longue date et non-fumeuses, qui s'étaient rendues dans le même hôpital pour rendre visite à un parent ou ami. Les habitudes tabagiques des maris sont différentes entre les cas de SOC et les contrôles, mais les différences ne sont que marginalement statistiquement significatives. L'association est inconstante par rapport au nombre quotidien de cigarettes fumées, cependant la courbe dose-réponse en fonction du nombre total de cigarettes fumées au cours de la vie montre une progression régulière. Les femmes dont les maris ont fumé plus de 300000 cigarettes ont un risque relatif de développer un SOC de 1,8 (intervalle de confiance 90%: 0,9–3,6) par rapport aux femmes dont les maris n'ont jamais fumé. L'association décrite ici, ainsi que d'autres preuves concordantes, indiquent que l'exposition passive à la fumée de cigarettes peut être un facteur de risque pour la survenue du SOC.
Zusammenfassung
In einer Fall-Kontroll-Strdie wurden 103 Patientinnen mit chronisch obstruktiver Lungenkrankheit erfasst, die nie geraucht hatten und zur Zeit der Studie verheiratet waren oder es zumindest früher einmal gewesen waren. Als Kontrollen dienten 179 Frauen auf Krankenvisite im selben Spital, die ebenfalls nie geraucht hatten und auch zumindest einmal verheiratet gewesen waren. Verglichen wurden die Rauchgewohnheiten der Ehemänner. Der einfache Vergleich Raucher-Nichtraucher ergab eine schwach signifikante Differenz, ein eindeutiger Zusammenhang mit der täglich gerauchten Anzahl Zigaretten fand sich jedoch nicht. Eine dosisabhängige Beziehung zeigte sich bei der im Leben insgesamt gerauchten Anzahl Zigaretten: das relative Risiko war für Frauen, deren Ehemänner mehr als 300000 Zigaretten geraucht hatten 1,8 im Vergleich zu Partnerinnen von Nichtrauchern (90% Vertrauensintervall 0,9–3,6). Diese Resultate könnten ein Hinweis dafür sein, dass Nichtrauchen ein Risikofaktor für chronisch obstruktive Lungenkrankheiten sein könnte.
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Kalandidi, A., Trichopoulos, D., Hatzakis, A. et al. The effect of involuntary smoking on the occurence of chronic obstructive pulmonary disease. Soz Präventivmed 35, 12–16 (1990). https://doi.org/10.1007/BF01369539
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DOI: https://doi.org/10.1007/BF01369539