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Simultaneous acute infections with hepatitis non-A, non-B, and B viruses

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Summary

A case of overt acute hepatitis acquired through accidental needle stick was reported. The episode of hepatitis was classified as non-A, non-B because no hepatitis B marker or IgM-anti-HAV was detected during the peak of hepatitis. Concurrent with non-A, non-B hepatitis, subclinical acute hepatitis B virus infection might have developed as evidence byde novo hepatitis B seroconversion 6 weeks later. It was concluded that hepatitis B and non-A, non-B viruses can be transmitted simultaneously by the same carrier, and can acutely infect the recipient simultaneously with possible viral interference.

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References

  1. Miller WJ, Provast PJ, McAller WJ, Ittensohn OL, Villarejos VM, Hilleman MR: Specific immune adherence assay for human hepatitis A antibody. Application to diagnostic and epidemiologic investigations. Proc Soc Exp Biol Med 149:254–261, 1975

    PubMed  Google Scholar 

  2. Lemon SM, Brown CD, Brooks DS, Simons TE, Bancroft WH: Specific immunoglobulin M response to hepatitis A virus determined by solid-phase radioimmunoassay. Infect Immun 28:927–936, 1980

    PubMed  Google Scholar 

  3. Prince AM: An antigen detected in the blood during the incubation period of serum hepatitis. Proc Natl Acad Sci USA 60:814–821, 1968

    PubMed  Google Scholar 

  4. Irwin GR, Allen RG, Segae HG, Allen AM, Putnak JR, Cannon HG, Top FH Jr: Serodiagnosis of hepatitis B virus infection by antibody to core antigen. J Infect Dis 136:31–36, 1977

    PubMed  Google Scholar 

  5. Feinstone SM, Kapikian AZ, Purcell RH, Alter HJ, Holland PV: Transfusion-associated hepatitis not due to viral hepatitis type A or B. N Engl J Med 292:767–770, 1975

    PubMed  Google Scholar 

  6. Karvountzis GG, Mosley JW, Redeker AG: Serologic characterization of patients with two episodes of acute viral hepatitis. Am J Med 58:815–822, 1975

    PubMed  Google Scholar 

  7. Mosley JW, Redeker AG, Feinstone SM, Purcell RH: Multiple hepatitis viruses in multiple attacks of acute viral hepatitis. N Engl J Med 296:75–78, 1977

    PubMed  Google Scholar 

  8. Norkrans G, Frösner G, Hermodsson S, Iwarson S: Multiple hepatitis attacks in drug addicts. J Am Med Assoc 243:1056–1058, 1980

    Google Scholar 

  9. Dietzman DE, Mattew EB, Madden DL: The occurrence of epidemic infectious hepatitis in chronic carriers of Australia antigen. J Pediatr 80:577–582, 1972

    PubMed  Google Scholar 

  10. Hindman SH, Maynard JE, Bradley DW, Berguist KR, Denes AE: Simultaneous infection with type A and B hepatitis viruses. Am J Epidemiol 105:135–139, 1977

    PubMed  Google Scholar 

  11. Drucker J, Tabor E, Gerety RJ, Jackson D, Barker LF: Simultaneous acute infection with hepatitis A and hepatitis B viruses in chimpanzee. J Infect Dis 139:338–342, 1979

    PubMed  Google Scholar 

  12. Mathiesen LR, Hardt SF, Nielson JO, Sloth K, Zoffmann H, Møller AM, Wong D, Purcell RH and the Copenhagen hepatitis acute programme: Epidemiology and clinical characteristics of acute hepatitis types A, B, and non-A, non-B. Scand J Gastroenterol 14:849–856, 1979

    PubMed  Google Scholar 

  13. Hoofnagle JH, Gerety RJ, Barker LF: Antibody to hepatitis-B-virus core in man. Lancet 2:869–873, 1973

    PubMed  Google Scholar 

  14. Hoofnagle JH, Seeff LB, Bales ZB, Gerety RJ, Tabor E: Serologic responses in HB.In Viral Hepatitis, GN Vyas, SN Cohen, R Schmid (eds), Philadelphia, Franklin Institute Press, 1978, pp 219–242

    Google Scholar 

  15. Gerlich WH, Lüer W, Thomseen R, and the study group for viral hepatitis of the Deutsche Forschungsgemeinschaft: Diagnosis of acute and inapparent hepatitis B virus infections by measurement of IgM antibody to hepatitis B core antigen. J Infect Dis 142:95–101, 1980

    PubMed  Google Scholar 

  16. Chen DS, Lai MY, Yu JY, Wang TH, Sung JL, Lai MS: Laboratory evaluation of commercial γ-globulin in the protection against viral hepatitis A and B. Trans Gastroenterol Soc ROC 9:48–49, 1980

    Google Scholar 

  17. Seeff LB, Hoofnagle JH: Immunrprophylaxis of viral hepatitis. Gastroenterology 77:161–182, 1979

    PubMed  Google Scholar 

  18. Hoofnagle JH, Seeff LB, Bales ZB, Wright EC, Zimmerman HJ, Veterans Administration Cooperative Study Group: Passive-active immunity from HBIG: Reanalysis of a veterans administration cooperative study of needle-stick hepatitis. Ann Intern Med 91:813–818, 1979

    PubMed  Google Scholar 

  19. Hoofnagle JH, Waggoner JG: Hepatitis A and B virus markers in immune serum globulin. Gastroenterology 78:259–263, 1980

    PubMed  Google Scholar 

  20. Dulbecco R, Ginsberg HS: Interference with viral multiplication.In Microbiology, 2nd ed, BD Davis, R Dulbecco, HN Eisen, HS Ginsberg, WB Wood, Jr (eds). New York, Harper and Row, 1973, pp 1172–1187

    Google Scholar 

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Authors and Affiliations

  1. Liver Unit, Chang-Gung Memorial Hospital, Lin-Kou Medical Center, 199, Tung Hwa North Road, Taipei, Taiwan, Republic of China

    Yun-Fan Liaw MD, Chia-Ming Chu MD, Chi-Sin Chang-Chien MD & Cheng-Shyong WU MD

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  1. Yun-Fan Liaw MD
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  2. Chia-Ming Chu MD
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  3. Chi-Sin Chang-Chien MD
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  4. Cheng-Shyong WU MD
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Liaw, YF., Chu, CM., Chang-Chien, CS. et al. Simultaneous acute infections with hepatitis non-A, non-B, and B viruses. Digest Dis Sci 27, 762–764 (1982). https://doi.org/10.1007/BF01393772

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  • DOI: https://doi.org/10.1007/BF01393772

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