Summary
We report 80 supratentorial lobar ependymomas, including 46 recurrences. All underwent operation. In the total collection 34.5% survived for more than 5 years. The behaviour of children and adults was nearly identical. Based on a histological grading into three steps of malignancy (E 1, E 2, E 3), the ependymomas in low grade 1 showed a 5 years' survival time of 41.5%. Compared to a 28.5% survival in group E 2 at the same time. Results in group E 3, which histologically resembled malignant glioma or glioblastoma, are not relevant because of the small number of cases. More than 50% of the E 1 recurrences showed transformation to E 2. No transformation into a lower grade of malignancy has been observed.
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Afra, D., Müller, W., Slowik, F. et al. Supratentorial lobar ependymomas: Reports on the grading and survival periods in 80 cases, including 46 recurrences. Acta neurochir 69, 243–251 (1983). https://doi.org/10.1007/BF01401811
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DOI: https://doi.org/10.1007/BF01401811