Abstract
We evaluated serum levels of calcium-related factors and bone mineral content in 40 healthy elderly female subjects (mean age ± SD, 79 ± 7 years) as possible factors relating to calcification of the abdominal aorta. There were no significant differences in serum levels of total cholesterol, triglycerides, and estradiol between elderly female subjects with and without calcification of the abdominal aorta. Elderly female subjects with calcification of the abdominal arota, when compared to those without calcification, showed significantly reduced values of bone mineral content of the distal radius. Moreover, the elderly female subjects with calcification of the abdominal aorta showed significant increases in serum levels of parathyroid hormone and calcitonin, and significantly decreased levels of 24,25-dihydroxyvitamin D3. There were no significant differences in serum levels of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3. These data suggest that elevated secretion of parathyroid hormone plays an important role in the development of calcification of the abdominal aorta.
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Koh, E., Morimoto, S., Tamatani, M. et al. Hyperparathyroidism as a cause of calcification of the abdominal aorta in elderly female subjects. J Bone Miner Metab 14, 35–38 (1996). https://doi.org/10.1007/BF01771672
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DOI: https://doi.org/10.1007/BF01771672