Abstract
The personal series of 12 nonfunctioning islet cell tumors (NFIT) of the pancreas is reported. The ultrasound and computed tomography features of NFIT are analyzed, and a few signs are identified that may be useful in the differential diagnosis vs ductal carcinoma. The necessity to complete the diagnostic work up by means of fine needle aspiration biopsy and cytologic smears is also emphasized.
Similar content being viewed by others
References
Kent RB III, Van Heerden JA, Weiland LH: Nonfunctioning islet cell tumors.Ann Surg 193:185–190, 1981
Broder LE, Carter SK: Pancreatic islet cell carcinoma. I. Clinical features of 52 patients.Ann Intern Med 79:101–107, 1973
Cubilla AL, Hajdu SI: Islet cell carcinoma of the pancreas.Arch Pathol Lab Med 99:204–207, 1975
Dial PF, Braasch JW, Rossi RL, Lee AK, Jin G: Management of nonfunctioning islet cell tumors of the pancreas.Surg Clin North Am 65:291–299, 1985
Broughan TA, Leslie JD, Soto JM, Hermann RE: Pancreatic islet cell tumors.Surgery 99:671–678, 1986
Eelkema EA, Stephens DH, Ward EM, Sheedy PF II: CT features of nonfunctioning islet cell carcinoma.AJR 143:943–948, 1984
Eckhauser FE, Cheung PS, Vinik AI, Strodel WE, Lloyd RV, Thompson NW: Nonfunctioning malignant neuroendocrine tumors of the pancreas.Surgery 100:978–988, 1986
Hancke S: Localization of hormone-producing gastrointestinal tumours by ultrasonic scanning.Scand J Gastroenterol 14 (suppl 53):115–116, 1979
Dunnick NR, Doppman JL, Mills SR, McCarthy DM: Computed tomographic detection of nonbeta pancreatic islet cell tumors.Radiology 135:117–120, 1980
Kuhn FP, Günther RW, Rückert K, Beyer J: Ultrasonic demonstration of small pancreatic islet cell tumors.J Clin Ultrasound 10:173–175, 1982
Günther RW, Klose KJ, Rückert K, Kuhn FP, Beyer J, Klotter HJ, Cordes U: Islet-cell tumors: detection of small lesions with computed tomography and ultrasound.Radiology 148:485–488, 1983
Krudy AG, Doppman JL, Jensen RT, Norton JA, Collen MJ, Shawker TH, Gardner JD, McArthur K, Gorden P: Localization of islet cell tumors by dynamic CT: comparison with plain CT, arteriography, sonography, and venous sampling.AJR 143:585–589, 1984
Günther RW, Klose KJ, Rückert K, Beyer J, Kuhn FP, Klotter HJ: Localization of small islet-cell tumors: preoperative and intraoperative ultrasound, computed tomography, arteriography, digital subtraction angiography, and pancreatic venous sampling.Gastrointest Radiol 10:145–152, 1985
Breatnach ES, Han SY, Rahatzad MT, Stanley RJ: CT evaluation of glucagonomas.JCAT 9:25–29, 1985
Rossi P, Baert A, Passariello R, Simonetti G, Pavone P, Tempesta P: CT of functioning tumors of the pancreas.AJR 144:57–60, 1985
Gorman B, Charboneau JW, James EM, Reading CC, Galiber AK, Grant CS, Van Heerden JA, Telander RL, Service FJ: Benign pancreatic insulinoma: preoperative and intraoperative sonographic localization.AJR 147:929–934, 1986
Galiber AK, Reading CC, Charboneau JW, Sheedy PF II, James EM, Gorman B, Grant CS, Van Heerden JA, Telander RL: Localization of pancreatic insulinoma: comparison of pre- and intraoperative US with CT and angiography.Radiology 166:405–408, 1988
Stark DD, Moss AA, Goldberg HI, Deveney CW: CT of pancreatic islet cell tumors.Radiology 150:491–494, 1984
Kolmannskog F, Schrumpf E, Vaines K: Computed tomography and angiography in pancreatic apudomas and cystadenomas.Acta Radiol (Diagnosis) 23:365–372, 1982
Gold J, Rosenfield AT, Sostman D, Burrell M, Taylor KJW: Nonfunctioning islet cell tumors of the pancreas: radiographic and ultrasonographic appearances in two cases.AJR 131:715–717, 1978
Frija J, Schmit P, Vadrot D, Katz M, Laval-Jeantet M: Non-secreting islet cell adenoma of the pancreas evaluated by computed tomography and sonography. Report of a case.Eur J Radiol 2:160–161, 1982
Stewart R, Sirinek KR, Levine BA: The asymptomatic pancreatic islet cell tumor: a novel presentation.Surgery 100:108–112, 1986
Cohen DJ, Fagelman D: Pancreas islet cell carcinoma with complete fatty replacement: CT characteristics.JCAT 10:1050–1051, 1986
Gudjonsson B: Cancer of the pancreas. 50 years of surgery.Cancer 60:2284–2303, 1987
Moertel CG, Hanley JA, Johnson LA: Streptozocin alone compared with streptozocin plus fluorouracil in the treatment of advanced islet cell carcinoma.New Engl J Med 303:1189–1194, 1980
Torrisi JR, Treat J, Zeman R, Dritschilo A: Radiotherapy in the management of pancreatic islet cell tumors.Cancer 60:1226–1231, 1987
Adler O, Kaftori JK, Rosenberger A, Ben Arieh J: Non-functioning islet cell tumours of the pancreas. A review of radiological literature and a report on two cases.Röfo 127:559–563, 1977
Fugazzola C, Bergamo Andreis IA, Portuese A, Procacci C, Iacono C, Jannucci A, Cinquino M, Della Sala S, Mansueto G: Tumori cistici del pancreas. Apporto diagnostico dell'ecografia e della tomografia computerizzata. In: Rizzatto G Solbiati L Derchi L Busilacchi P (eds):Imaging-US, Avanzamenti '88 Milano: Masson, 1989, pp 119–129
Friedman AC, Lichtenstein JC, Fishman EK, Oertel JE, Dachman AH, Siegelman SS: Solid and papillary epithelial neoplasm of the pancreas.Radiology 154:333–337, 1985
Weiland LH: Frozen section diagnosis in tumors of the pancreas.Sem Diagn Pathol 1:54–58, 1984
Hsiu JG, D'Amato NA, Sperling MH, Greenspan M, Jaffe AH, Smith R III, De La Torre R: Malignant islet-cell tumor of the pancreas diagnosed by fine needle aspiration biopsy. A case report.Acta Cytol 29:576–579, 1985
Larsson LI: Endocrine pancreatic tumors.Human Pathol 9:401–416, 1978
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Fugazzola, C., Procacci, C., Andreis, I.A.B. et al. The contribution of ultrasonography and computed tomography in the diagnosis of nonfunctioning islet cell tumors of the pancreas. Gastrointest Radiol 15, 139–144 (1990). https://doi.org/10.1007/BF01888758
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01888758