Abstract
Hemimegalencephaly is a rare malformation characterized by overdevelopment of one cerebral hemisphere. The opposite hemisphere is usually normal. This paper presents a 2-day-old patient with hemimegalencephaly associated with diffuse volume loss in the contralateral hemisphere. To the best of the author's knowledge such an association has not been reported previously. This finding suggested that these patients may suffer from a congenital hemispheral insult of varying degree of severity and variable time of onset.
References
Barkovich AJ, Chuang SH (1990) Unilateral megalencephaly: correlation of MR imaging and pathologic characteristics. AJNR 11:523
Cavenagh EC, Hart BL, Rose D (1993) Association of linear sebaceous nevus syndrome and unilateral megalencephaly. AJNR 14:405
Bignami A, Palladini G, Zapella M (1968) Unilateral megalencephaly with nerve cell hypertrophy. An anatomical and quantitative histochemical study. Brain Res 9: 103
Manz HJ, Phillips TM, Rowden G, McCullough DC (1979) Unilateral megalencephaly, cerebral cortical dysplasia, neuronal hypertrophy, and heterotopia: cytomorphometric, fluorometric, cytochemical, and biochemical analyses. Acta Neuropathol (Berl) 45:97
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Sener, R.N. Hemimegalencephaly associated with contralateral hemispheral volume loss. Pediatr Radiol 25, 387–388 (1995). https://doi.org/10.1007/BF02021717
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DOI: https://doi.org/10.1007/BF02021717