Abstract
A group of 25 children affected by different degrees of psychomotor retardation (severe (n=13); mild-moderate (n=12)) and symptoms suggesting gastro-oesophageal reflux (GOR) underwent oesophageal manometry and oesophageal pH monitoring. Of these patients, 21 (84%) were affected by GOR. In all children with severe brain damage and GOR (12/13), oesophageal manometry showed marked motility abnormalities that persisted after cure of GOR. In patients with minor retardation and GOR (9/12), oesophageal manometry showed normal motility or a less severe degree of oesophageal motor dysfunction which improved after curing the GOR. These results suggest that oesophageal motor dysfunction is a frequent occurrence in children affected by severe psychomotor retardation and GOR.
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Abbreviations
- GOR:
-
gastro-oesophageal reflux
- LOS:
-
lower oesophageal sphincter
- UOS:
-
upper oesophageal spincter
References
Alford CA (1977) Prenatal infections and psychosocial development in children born into lower socioeconomic settings. In Mittler P (ed) Research to practice in mental retardation and biomedical aspects, vol III. University Park Press. Baltimore, pp 171–178
Byrne WJ, Campbell M, Ashcraft E, Seibert JJ, Euler AR (1983) A diagnostic approach to vomiting in severely retarded patients. Am J Dis Child 137:259–262
Clouse RE, Staiano A (1983) Contraction abnormalities of the esophageal body in patients referred for manometry. A new approach tomanometric classification. Dig Dis Sci 9:784–791
Cucchiara S, Staiano A, Di Lorenzo C, D'Ambrosio R, Andreotti MR, Prato M, De Filippo P, Auricchio S (1986) Esophageal motor abnormalities in children with gastroesophageal reflux and peptic esophagitis. J Pediatr 108:907–910
Cucchiara S, Staiano A, Boccieri A, De Stefano M, Capozzi C, Manzi G, Camerlingo F, Paone FM (1990) Effects of cisapride on parameters of esophageal motility and on the prolonged intraesophageal pH test in infants with gastroesophageal reflux disease. Gut 31:21–25
Cucchiara S, Staiano A, Gobio Casali L, Boccieri A, Paone FM (1990) Value of the 24-hour intraesophageal pH monitoring in children. Gut 31:129–133
Hillemeier AC, Grill BB, McCallum R, Gryboski J (1983) Esophageal and gastric motor abnormalities in gastroesophageal reflux during infancy. Gastroenterology 84:741–745
Katz PO, Knuff TE, Benjamin SB, Castell DO (1986) Abnormal esophageal pressures in reflux esophagitis: cause or effect? Am J Gastroenterol 81:744–746
Sondheimer JM, Morris BA (1979) Gastroesophageal reflux among severely retarded children. J Pediatr 94:710–714
Staiano A, Cucchiara S, De Vizia B, Andreotti MR, Auricchio S (1987) Disorders of upper esophageal sphincter motility in children. J Pediatr Gastroenterol Nutr 6:892–898
Worster-Drought C (1974) Suprabulbar paresis. Dev Med Child Neurol [Suppl]:30–31
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Staiano, A., Cucchiara, S., Del Giudice, E. et al. Disorders of oesophageal motility in children with psychomotor retardation and gastro-oesophageal reflux. Eur J Pediatr 150, 638–641 (1991). https://doi.org/10.1007/BF02072624
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DOI: https://doi.org/10.1007/BF02072624