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Konstitution des Aldosterons, des neuen Mineralocorticoids

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Summary

Chemical degradation of the new crystalline mineralocorticoid provisionally called electrocortin has shown that this compound is 11β, 21-dihydroxy-3, 20-diketo-4-pregnen-18-al. In solution this reacts mainly as the 11-hemiacetal. We suggest aldosterone as a definitive name for the compound.

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References

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Authors and Affiliations

  1. The Middlesex Hospital Medical School, London W. 1

    S. A. Simpson, J. F. Tait, A. Wettstein, R. Neher, J. v. Euw, O. Schindler & T. Reichstein

  2. Forschungslaboratorium der Ciba Aktiengesellschaft, Basel

    S. A. Simpson, J. F. Tait, A. Wettstein, R. Neher, J. v. Euw, O. Schindler & T. Reichstein

  3. organisch-chemische Anstalt der Universität Basel, Switzerland

    S. A. Simpson, J. F. Tait, A. Wettstein, R. Neher, J. v. Euw, O. Schindler & T. Reichstein

Authors
  1. S. A. Simpson
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  2. J. F. Tait
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  3. A. Wettstein
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  4. R. Neher
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  5. J. v. Euw
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  6. O. Schindler
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  7. T. Reichstein
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Additional information

Über Bestandteile der Nebennierenrinde und verwandte Stoffe, 90. Mitteilung.

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Simpson, S.A., Tait, J.F., Wettstein, A. et al. Konstitution des Aldosterons, des neuen Mineralocorticoids. Experientia 10, 132–133 (1954). https://doi.org/10.1007/BF02158515

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