Summary
A number of basically substituted benzimidazoles show a strong analgesic activity in mice, rats, rabbits, and dogs. Qualitatively they act very similarly to morphine and corresponding synthetic analgetics and the most active of these compounds are quantitatively superior to all analgetics hitherto described.
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Gross, F., Turrian, H. Über Benzimidazolderivate mit starker analgetischer Wirkung. Experientia 13, 401–403 (1957). https://doi.org/10.1007/BF02161117
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DOI: https://doi.org/10.1007/BF02161117