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The Zurich Study

XVIII. Obsessive-compulsive disorders and syndromes in the general population

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Summary

The cross-sectional and longitudinal association between obsessive-compulsive syndrome (OCS) and other psychiatric problems and the course over 11 years was examined in a Swiss cohort of young adults. As the prevalence of obsessive-compulsive disorders, defined according to the DSM-III was very low (n=5), we applied a lower diagnostic threshold based on obsessive-compulsive symptoms and social impairment, to define an OCS. The weighted lifetime prevalence rate for OCS at age 30 years was 5.5%. The mean age of onset was 17.1±4.9 years for males, and 19.1±5.1 year for females. OCS was associated with all subtypes of depressive disorders as well as with social phobia and agoraphobia. Although the longitudinal analysis showed no stability at the diagnostical level, there was some stability on the symptom level. Perhaps subjects with OCS learned in time to cope and to live with their symptoms without suffering.

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Authors and Affiliations

  1. Research Department, Psychiatric University Hospital Zurich, P. O. Box 68, CH-8029, Zurich, Switzerland

    Martina Degonda, Maja Wyss & Jules Angst

Authors
  1. Martina Degonda
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  2. Maja Wyss
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  3. Jules Angst
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Additional information

This project was supported by grant 32-9502/3.873.0.88 from the Swiss National Science Foundation. The authors thank Dr. Kathleen R., Merikangas, Genetic Epidemiology Research Unit, Department of Psychiatry, Yale Univers., New Haven/USA and Dr. Cécile Ernst, Psychiatric University Hospital Zurich, CH-8029 Zurich/Switzerland for their valuable comments.

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Degonda, M., Wyss, M. & Angst, J. The Zurich Study. Eur Arch Psychiatry Clin Nuerosci 243, 16–22 (1993). https://doi.org/10.1007/BF02191519

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  • DOI: https://doi.org/10.1007/BF02191519

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