Abstract
Salzmann's corneal dystrophy develops from proliferation of connective tissue in a pannus area. Vascular connective tissue apparently becomes avascular in the course of time. In addition, spheroid (keratinoid, elastotic) microglobular homogenous or granular deposits appear, as in other chronic corneal disturbances.
Zusammenfassung
Zur Salzmannschen Hornhautdystrophie kommt es durch Proliferation von Bindegwebe im Bereiche eines Pannus. Es wird dabei offenbar vaskularisiertes Bindegewebe im Laufe der Zeit gefäßfrei. Zusätzlich treten — wie bei anderen chronischen Hornhautschädigungen — sphäroidale (keratinoide, elastotische) kleinstkugelige, homogene oder granulierte Einlagerungen auf.
Similar content being viewed by others
Literatur
Bischler V (1946) La dystrophie cornéene nodulaire de Salzmann. Ophthalmologica, 111:111–119
Brown EVL, Katz D (1935) Salzmann's nodular corneal dystrophy, its pathologic process and successful therapy. Arch Ophthalmol 13:598–613
Brownstein S, Fine BS, Sherman ME, Zimmerman LE (1974) Granular dystrophy of the cornea. Light and electronmicroscopic confirmation of recurrence in a graft. Amer J Ophthal 77: 701
Brownstein S, Rodrigues MM, Fine BS and Albert EN (1973) The elastotic nature of hyaline corneal deposits. Am J Ophthalmol 75:799–809
Etienne R, Moreau PG (1957) La dystrophie cornéenne nodulaire de Salzmann. Annales d'Oculist 190:187–205
Fraunfelder FT, Hanna C (1973) Spheroidal degeneration of cornea and conjunctiva. 3. Incidences classification, and etiology. Am J Ophthalmol 76:41
Fuchs E (1902) Über knötchenförmige Hornhauttrübung. Graefes Arch f Ophth 53:423
Garner A (1970) Keratinoid degeneration of the cornea. Brit J Ophthal 54:769–780
Garner A, Fraunfelder FT, Barras TC, Hinzpeter EN (1976) Spheroidal degeneration of the cornea and conjunctiva. Brit J Ophthal 60:473
Garner A, Morgan G, and Tripathi RC (1973) Climatic droplet keratopathy. Pathologic findings. Arch Ophthalmol 89:198
Hanna C, Fraunfelder FT (1972) Spheroidal degeneration of the cornea and conjunctiva. Amer J Ophthal 74:829
Hogan M, Zimmerman LE (1962) Ophthalmic Pathology. Saunders, Philadelphia
Houber JP (1970) Récidive bilatérale d'une dégénérescence nodulaire de Salzmann apres greffe perforante de la cornée. Ophthalmologica 161:90–97
Katz D (1953) Salzmann's nodular corneal dystrophy. Acta Ophthalm 31:377–383
Kenyon KR (1969) The synthesis of basement membrane by the corneal epithelium in bullous keratopathy. Invest. Ophthalmol. 8:156
Ladekarl PM (1930) Two atypical cases of keratitis nodosa Groenouw with histological examinations. Acta Ophthalmol 8:213
Leuenberger PM, Gnadinger MC, Cabernard E (1973) Zur Frage der Kollagensynthese durch corneales Epithel. Albrecht von Graefe's Arch. Klin Ophthalmol 187:171
Muir EB (1940) Salzmann's nodulair dystrophy. Amer Journ Ophth 23:138–144
Rodrigues MM, Laibson PR, Weinreb S (1975) Corneal elastosis. Arch Ophthal 93:111
Salzmann M (1925) Über eine Abart der knötchenförmigen Hornhautdystrophie. Zeitsch f Augenheilk 57:92
Vannas A, Hogan MJ, Wood J (1975) Salzmann's nodular degeneration of the cornea. Am J Ophth 79:211–219
Yanoff M, Fine BS (1975) Ocular Pathology. Harper and Row Hegerstown, Maryland
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Pau, H., Schmitt-Gräff, A. Salzmannsche Hornhautdystrophie (knötchenförmige Hornhautdegeneration). Graefe's Arch Clin Exp Ophthalmol 218, 161–167 (1982). https://doi.org/10.1007/BF02215657
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02215657