Abstract
A 68-year-old woman was admitted to our hospital because of left ventricular failure. Myocardial perfusion single-photon emission computed tomography demonstrated a non-reversible perfusion defect in the anterolateral left ventricular segments and reduced ejection fraction, findings consisted with ischemic cardiomyopathy accompanied by lateral wall infarction. Coronary angiogram was normal, but the left ventriculogram showed prominent trabeculations in the apical and anterolateral segments. The left ventricular ejection fraction was 28%. Cine magnetic resonance imaging demonstrated prominent trabeculations and deep intertrabecular recesses, findings consistent with noncompaction of the ventricular myocardium. Myocardial hypoperfusion or necrosis in the noncompacted myocardium may be the cause of myocardial damage and possibly the basis of left ventricular failure.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Chin TK, Perloff JK, Williams RG, Jue K, Mohrmann R. Isolated noncompaction of the left ventricular myocardium. A study of eight cases.Circulation 1990; 82:507–513.
Oechslin EN, Attenhofer Jost CH, Rojas JR, Kaufman PA, Jenni R. Long-term follow up of 34 adults with isolated left ventricular noncompaction: a distinct cardiomyopathy with poor prognosis.J Am Coll Cardiol 2000; 36:493–500.
Junga G, Kneifel S, Smekal AV, Steiner H, Bauersfeld U. Myocardial ischemia in children with isolated ventricular non-compaction.Eur Heart J 1999; 20:910–916.
Soler R, Rodriguez E, Monserrat L, Alvarez N. MRI of subendocardial perfusion deficits in isolated left ventricular noncompaction.J Comput Assist Tomogr 2002; 26:373–375.
Borges AC, Kivelitz D, Baumann G. Isolated left ventricular non-compaction: cardiomyopathy with homogeneous transmural and heterogeneous segmentai perfusion.Heart 2003; 89:e20.
Mamede M, Tadamura E, Hosokawa R, Ohba M, Kubo S, Yamamuro M, et al. Comparison of myocardial blood flow induced by adenosine triphosphate and dipyridamole in patients with coronary artery disease.Ann Nucl Med 2005; 19:711–717.
Jeni R, Oechslin E, Schneider J, Jost CA, Kaufman PA. Echocardiographic and pathoanatomical characteristics of isolated left ventricular noncompaction: a step towards classification as a distinct cardiomyopathy.Heart 2001; 86:666–671.
Petersen SE, Selvanayagam JB, Wiesmann F, Robson MD, Francis JM, Anderson RH, et al. Left ventricular non-compaction. Insights from cardiovascular magnetic resonance imaging.J Am Coll Cardiol 2005; 46:101–105.
Hook S, Ratliff NB, Rosenkranz E, Sterba R. Isolated non-compaction of the ventricular myocardium.Pediatr Cardiol 1996; 17:43–45.
Ichida F, Hamamichi Y, Miyawaki T, Ono Y, Kamiya T, Akagi T, et al. Clinical features of isolated noncompaction of the ventricular myocardium: long-term clinical course, hemodynamic properties, and genetic background.J Am Coll Cardiol 1999; 34:233–240.
Daimon Y, Watanabe S, Takeda S, Hijikata Y, Komuro I. Two-layered appearance of noncompaction of the ventricular myocardium on magnetic resonance imaging.Circ J 2002; 66:619–621.
Korcyk D, Edwards CC, Armstrong G, Christiansen JP, Howitt L, Sinclair T, et al. Contrast-enhanced cardiac magnetic resonance in a patient with familial isolated ventricular non-compaction.J Cardiovasc Magn Reson 2004; 6:569–576.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Matsumoto, N., Sato, Y., Kunimasa, T. et al. Noncompaction of the ventricular myocardium mimicking ischemic cardiomyopathy. Ann Nucl Med 20, 639–641 (2006). https://doi.org/10.1007/BF02984663
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02984663