Abstract
In a quantitative SPECT study with multiple radionuclides, it is very important to eliminate the counts of scattered photons from planar images. In this paper, the triple energy window (TEW) method, which has developed to eliminate the counts of scatter photons in measured counts, was applied to a multiradionuclide SPECT study and its effect was examined in a simulation study. In the simulation, we used Tc-99m and Tl-201, and we assumed their photopeak energies to be 141 and 73 keV, respectively. For two different activity distributions in a cylinder phantom, simulation tests with Tl-201 and Tc-99m gave good agreement between the activity distributions reconstructed from primary photons and those from corrected data. The contrast of a cold spot area in images with and without correction improved around 70% to more than 96%.
Similar content being viewed by others
References
Ogawa K, Harata Y, Ichihara T, Kubo A, Hashimoto S. Estimation of scatter component in SPECT planar image using a Monte Carlo method.Jpn J Nucl Med 27: 467–475, 1990.
Floyd CE, Jaszczak RJ, Harris CC, Coleman RE. Energy and spatial distribution of multiple order Compton scatter in SPECT: a Monte Carlo simulation.Phys Med Biol 29: 1217–1230, 1984.
Floyd CE, Jaszczak RJ, Coleman RE. Inverse Monte Carlo: A Unified Reconstruction Algorithm for SPECT.IEEE Trans Nucl Sci 32: 779–785, 1985.
Axelsson B, Msaki B, Israelsson A. Subtraction of Comptonscattered photons in single-photon emission computerized tomography.J Nucl Med 25: 490–494, 1984.
Jaszczak RJ, Greer KL, Floyd CE, Harris CC, Coleman RE. Improved SPECT quantification using compensation for scattered photons.J Nucl Med 25: 893–900, 1984.
Koral KF, Swailem FM, Buchbinder S, Clinthone NH, Rogers WL, Tsui BMW. SPECT dual-energy-window Compton Correction: Scatter Multiplier Required for Quantification.J Nucl Med 31: 90–98, 1990.
Hamill JJ, DeVito RP. Scatter reduction with energy-weighted acquisition.IEEE Trans Nucl Sci 36: 1334–1339, 1989.
Koral KF, Wang X, Rogers WL, Clinthorne NH, Wang X. SPECT Compton-scattering correction by analysis of energy spectra.J Nucl Med 29: 195–202, 1988.
Gagnon D, Todd-Pokropek AE, Arsenault A, Dupras G. Introduction to holospectral imaging in nuclear medicine for scatter subtraction.IEEE Trans Med Imag 8: 245–250, 1989.
Floyd CE, Jaszczak RJ, Coleman RE. Scatter detection in SPECT imaging: dependence on source depth, energy, and energy window.Phys Med Biol 33: 1075–1081, 1988.
Koral KF, Clinthorne NH, Rogers WL. Improving emission-computed-tomography quantification by Comptonscatter rejection through offset window.Nucl Inst and Methods in Phys Res A242: 610–614, 1986.
King MA, Hademenos GJ, Glick SJ. A dual photopeak window method for scatter correction.J Nucl Med 33: 605–612, 1992.
Ogawa K, Harata Y, Ichihara T, Kubo A, Hashimoto S. A Practical method for position-dependent Compton-scatter correction in single photon emission CT.IEEE Trans Med Imag 10: 408–412, 1991.
Ichihara T, Ogawa K, Motomura N, Kubo A, Hashimoto S. Compton scatter correction using triple-energy window method for single- and dual-isotope SPECT.J Nucl Med 34: 2216–2221, 1993
Raeside DE. Monte Carlo principles and applications.Phys Med Biol 21: 181–197, 1976.
Ogawa K, Takagi Y, Kubo A, Hashimoto S, Sanmiya T, Okano Y, et al. An attenuation correction method of single photon emission computed tomography using gamma ray transmission CT.KAKU IGAKU (Jpn JNucl Med) 22: 477–490, 1985.
Chang LT. A method for attenuation correction in radionuclide computed tomography.IEEE Trans Nucl Sci 25: 638–642, 1978.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ogawa, K. Simulation study of triple-energy-window scatter correction in combined Tl-201, Tc-99m SPECT. Ann Nucl Med 8, 277–281 (1994). https://doi.org/10.1007/BF03165031
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF03165031