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11.01.2016 | Original article

Association of monocyte/HDL-C ratio with SYNTAX scores in patients with stable coronary artery disease

verfasst von: H. Kundi, MD, E. Kiziltunc, MD, M. Cetin, MD, H. Cicekcioglu, MD, Z. G. Cetin, MD, G. Cicek, MD, E. Ornek, MD

Erschienen in: Herz | Ausgabe 6/2016

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Abstract

Purpose

The aim of this study was to investigate the relationship between monocyte count/high density lipoprotein cholesterol (HDL-C) ratio (MHR) and the severity of coronary atherosclerosis, as assessed by the SYNTAX score (SXscore), in patients with stable coronary artery disease (CAD) undergoing coronary angiography.

Materials and methods

A total of 428 patients were included in the study between March 2012 and February 2015. The SXscore was determined with baseline coronary angiography. An SXscore ≥ 23 was regarded as severe CAD by definition, and the patients were divided into two groups: those with low SXscores (< 23) and those with high SXscores (≥ 23).

Results

MHR and C-reactive protein (CRP) were significantly higher in patients with high SXscores (p < 0.001 and p < 0.001, respectively). Left ventricular ejection fraction (LVEF) was lower in the group with high MHR and high SXscores. The cutoff value of MHR that predicted a high SXscore was 24, with a sensitivity of 66 % and a specificity of 65.1 %.

Conclusion

To the best of our knowledge, this is the first study in the literature showing that MHR is significantly associated with SXscores. Our results suggest that MHR can be used as a prognostic marker in patients with stable CAD, since it is an easily available and inexpensive test.

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Titel: Association of monocyte/HDL-C ratio with SYNTAX scores in patients with stable coronary artery disease
verfasst von: H. Kundi, MD
E. Kiziltunc, MD
M. Cetin, MD
H. Cicekcioglu, MD
Z. G. Cetin, MD
G. Cicek, MD
E. Ornek, MD
Publikationsdatum: 11.01.2016
Verlag: Springer Medizin
Erschienen in: Herz / Ausgabe 6/2016
Print ISSN: 0340-9937
Elektronische ISSN: 1615-6692
DOI: https://doi.org/10.1007/s00059-015-4393-1

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Association of monocyte/HDL-C ratio with SYNTAX scores in patients with stable coronary artery disease

Abstract

Purpose

Materials and methods

Results

Conclusion

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Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Purpose

Materials and methods

Results

Conclusion

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