Erschienen in:
04.01.2019 | Letter to the Editor
Comment to Impact of postmastectomy radiotherapy on the outcomes of breast cancer patients with T1-2 N1 disease; an individual patient data analysis of three clinical trials
verfasst von:
PD Dr. med. Christiane Matuschek, David Krug, Rainer J. Klement, René Baumann
Erschienen in:
Strahlentherapie und Onkologie
|
Ausgabe 4/2019
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Excerpt
Abdel-Rahman [
1] analyzed the overall survival-rate and disease-free survival of T1-2 N1 breast cancer patients after mastectomy, who were adjuvantly treated with various modern chemotherapeutic drugs (anthracyclines, taxanes) in 3 prospective phase III chemotherapy trials. His analysis suggested no potential benefits of an additional adjuvant postmastectomy radiotherapy (PMRT). The included trials were the BIG 02/98 [
6], the BCIRG 001 [
7] and the BCIRG-005 [
5] trials. The author concludes that in T1-2 N1 breast cancer patients who have received modern chemotherapy drugs PMRT does not provide any benefit for overall and disease-free survival. Prospective studies are necessary. …