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Erschienen in: Die Anaesthesiologie 11/2009

01.11.2009 | Klinische Pharmakologie

Was wissen wir über Narkosemechanismen?

Bewusstlosigkeit, Bewegungslosigkeit und Amnesie

verfasst von: Dr. V.-S. Eckle, C. Hucklenbruch, S.M. Todorovic

Erschienen in: Die Anaesthesiologie | Ausgabe 11/2009

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Zusammenfassung

Während der letzten Jahrzehnte verzeichnete die anästhesiologische Grundlagenforschung einen enormen Wissenszuwachs. Trotz neuer Erkenntnisse auf molekularer Ebene sind die Mechanismen, die Narkose vermitteln, weiterhin nicht vollständig geklärt. Der folgende Beitrag liefert einen knappen Überblick über einige anästhetikasensitive Ionenkanäle und ihre Modulation durch die klinisch gebräuchlichen Anästhetika Isofluran, Propofol und Ketamin. Die Teilaspekte der Allgemeinanästhesie Bewusstlosigkeit, Bewegungslosigkeit und Amnesie werden aufgegriffen und möglichen anatomischen Zielen zugeordnet.
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Metadaten
Titel
Was wissen wir über Narkosemechanismen?
Bewusstlosigkeit, Bewegungslosigkeit und Amnesie
verfasst von
Dr. V.-S. Eckle
C. Hucklenbruch
S.M. Todorovic
Publikationsdatum
01.11.2009
Verlag
Springer-Verlag
Erschienen in
Die Anaesthesiologie / Ausgabe 11/2009
Print ISSN: 2731-6858
Elektronische ISSN: 2731-6866
DOI
https://doi.org/10.1007/s00101-009-1618-9

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