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Incontinentia pigmenti

Herpes-simplex-Infektion als wichtige Differenzialdiagnose in der Neonatalperiode

Incontinentia pigmenti

Herpes simplex infection as an important differential diagnosis in the neonatal period

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Zusammenfassung

Wir berichten über ein 2 Tage altes, neugeborenes Mädchen mit herpetiform angeordneten Pusteln in disseminierter Verteilung. Es wird die Wichtigkeit einer ausführlichen Diagnostik bei Neugeborenen mit pustulösen Hautveränderungen herausgestellt, um die Differenzialdiagnosen Incontinentia pigmenti und einer kongenitalen Herpesinfektion abzugrenzen.

Abstract

In this article we present the case of a 2-day-old newborn girl in good general condition, with herpetic arranged pustules on the skin of her whole body. The case highlights the importance of a detailed diagnostic workup for newborns with pustular skin disease. Especially to differentiate between the diagnosis of incontinentia pigmenti and a congenital herpes infection.

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Literatur

  1. Berlin AL, Paller AS, Chan LS (2002) Incontinentia pigmenti: a review and update on the molecular basis of pathophysiology. J Am Acad Dermatol 47:169–187 (quiz 188–190)

    Article  PubMed  Google Scholar 

  2. Cohen BA (1987) Incontinentia pigmenti. Neurol Clin 5:361–377

    CAS  PubMed  Google Scholar 

  3. Detlefs RL, Frieden IJ, Berger TG et al (1987) Eosinophil fluorescence: a cause of false positive slide tests for herpes simplex virus. Pediatr Dermatol 4:129–133

    Article  CAS  PubMed  Google Scholar 

  4. Faloyin M, Levitt J, Bercowitz E et al (2004) All that is vesicular is not herpes: incontinentia pigmenti masquerading as herpes simplex virus in a newborn. Pediatrics 114:e270–e272

    Article  PubMed  Google Scholar 

  5. Folster-Holst R, Hoger P (2004) Pustular diseases of the newborn. J Dtsch Dermatol Ges 2:569–579

    Article  PubMed  Google Scholar 

  6. Kimberlin D (2004) Herpes simplex virus, meningitis and encephalitis in neonates. Herpes 11(Suppl 2):65A–76A

    PubMed  Google Scholar 

  7. Landy SJ, Donnai D (1993) Incontinentia pigmenti (Bloch-Sulzberger syndrome). J Med Genet 30:53–59

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Okan F, Yapici Z, Bulbul A (2008) Incontinentia pigmenti mimicking a herpes simplex virus infection in the newborn. Childs Nerv Syst 24:149–151

    Article  PubMed  Google Scholar 

  9. Sahn EE (1994) Vesiculopustular diseases of neonates and infants. Curr Opin Pediatr 6:442–446

    Article  CAS  PubMed  Google Scholar 

  10. Smahi A, Courtois G, Vabres P et al (2000) Genomic rearrangement in NEMO impairs NF-kappaB activation and is a cause of incontinentia pigmenti. The International Incontinentia Pigmenti (IP) Consortium. Nature 405(6785):466–472

    Article  CAS  PubMed  Google Scholar 

  11. Buckley DA, Munn SE, Higgins EM (2001) Neonatal eosinophilic pustular folliculitis. Clin Exp Dermatol 26:251–255

    Article  CAS  PubMed  Google Scholar 

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Correspondence to R. Fölster-Holst.

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A.-C. Rosenthal und R. Fölster-Holst geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren. Alle Patienten, die über Bildmaterial oder anderweitige Angaben innerhalb des Manuskripts zu identifizieren sind, haben hierzu ihre schriftliche Einwilligung gegeben.

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Rosenthal, AC., Fölster-Holst, R. Incontinentia pigmenti. Hautarzt 68, 149–152 (2017). https://doi.org/10.1007/s00105-016-3861-8

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  • DOI: https://doi.org/10.1007/s00105-016-3861-8

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