Skip to main content
Erschienen in: Der Internist 3/2013

01.03.2013 | Schwerpunkt

Endoskopische Submukosadissektion

verfasst von: Prof. Dr. J. Hochberger, P. Köhler, E. Kruse, J. Hûppertz, M. Delvaux, G. Gay, E. Wedi

Erschienen in: Die Innere Medizin | Ausgabe 3/2013

Einloggen, um Zugang zu erhalten

Zusammenfassung

Die endoskopische Submukosadissektion (ESD) wurde Ende der 1990er-Jahre in Japan entwickelt. Mittlerweile hat sie sich auch in Europa an zahlreichen Zentren fest etabliert. Sie stellt eine En-bloc-Schleimhautresektionstechnik zur Behandlung von Frühkarzinomen mit einem Durchmesser >1 cm sowie von flächigen Präkanzerosen dar, die mit bisherigen Schlingenresektionstechniken onkologisch oft nur unbefriedigend in mehreren Partikeln oder mit unsicherem lateralem Sicherheitsabstand abgetragen werden konnten. Bei der ESD wird die Läsion nach zirkulärer Markierung und großflächiger Unterspritzung mit einem Sicherheitsabstand von etwa 5 mm umschnitten und nachfolgend im Niveau der Submukosa mit einem 1–3 mm langen Diathermiemesserchen abgelöst. Die Methode stellt erhöhte technische Ansprüche an die Erfahrung des Untersuchers und ist zeitaufwendiger als die Schlingenresektion. In zahlreichen Studien zeigt sich jedoch eine klare Überlegenheit hinsichtlich R0-Resektionsrate und Lokalrezidivrate. In der vorliegenden Arbeit geben wir einen aktuellen Überblick über die ESD im oberen und unteren Gastrointestinaltrakt und zeigen Perspektiven des Verfahrens auf.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Kantsevoy SV, Adler DG, Conway JD et al (2008) Endoscopic mucosal resection and endoscopic submucosal dissection. Gastrointest Endosc 68:11–18PubMedCrossRef Kantsevoy SV, Adler DG, Conway JD et al (2008) Endoscopic mucosal resection and endoscopic submucosal dissection. Gastrointest Endosc 68:11–18PubMedCrossRef
2.
Zurück zum Zitat Saito Y, Uraoka T, Matsuda T et al (2007) Endoscopic treatment of large superficial colorectal tumors: a case series of 200 endoscopic submucosal dissections (with video). Gastrointest Endosc 66:966–973PubMedCrossRef Saito Y, Uraoka T, Matsuda T et al (2007) Endoscopic treatment of large superficial colorectal tumors: a case series of 200 endoscopic submucosal dissections (with video). Gastrointest Endosc 66:966–973PubMedCrossRef
3.
Zurück zum Zitat Endoscopic Classification Review Group (2005) Update on the Paris classification of superficial neoplastic lesions in the digestive tract. Endoscopy 37:570–578CrossRef Endoscopic Classification Review Group (2005) Update on the Paris classification of superficial neoplastic lesions in the digestive tract. Endoscopy 37:570–578CrossRef
4.
Zurück zum Zitat Tanaka S, Terasaki M, Hayashi N et al (2013) Warning for unprincipled colorectal endoscopic submucosal dissection: accurate diagnosis and reasonable treatment strategy. Dig Endosc (im Druck). DOI 10.1111/den.12016 Tanaka S, Terasaki M, Hayashi N et al (2013) Warning for unprincipled colorectal endoscopic submucosal dissection: accurate diagnosis and reasonable treatment strategy. Dig Endosc (im Druck). DOI 10.1111/den.12016
5.
Zurück zum Zitat Tanaka S, Terasaki M, Kanao H et al (2012) Current status and future perspectives of endoscopic submucosal dissection for colorectal tumors. Dig Endosc 24(Suppl 1):73–79PubMedCrossRef Tanaka S, Terasaki M, Kanao H et al (2012) Current status and future perspectives of endoscopic submucosal dissection for colorectal tumors. Dig Endosc 24(Suppl 1):73–79PubMedCrossRef
6.
Zurück zum Zitat Lambert R, Tanaka S (2012) Laterally spreading tumors in the colon and rectum. Eur J Gastroenterol Hepatol 24:1123–1134PubMedCrossRef Lambert R, Tanaka S (2012) Laterally spreading tumors in the colon and rectum. Eur J Gastroenterol Hepatol 24:1123–1134PubMedCrossRef
7.
Zurück zum Zitat Yoo JH, Shin SJ, Lee KM et al (2012) Risk factors for perforations associated with endoscopic submucosal dissection in gastric lesions: emphasis on perforation type. Surg Endosc 26:2456–2464PubMedCrossRef Yoo JH, Shin SJ, Lee KM et al (2012) Risk factors for perforations associated with endoscopic submucosal dissection in gastric lesions: emphasis on perforation type. Surg Endosc 26:2456–2464PubMedCrossRef
8.
Zurück zum Zitat Nagahama T, Yao K, Maki S et al (2011) Usefulness of magnifying endoscopy with narrow-band imaging for determining the horizontal extent of early gastric cancer when there is an unclear margin by chromoendoscopy (with video). Gastrointest Endosc 74:1259–1267PubMedCrossRef Nagahama T, Yao K, Maki S et al (2011) Usefulness of magnifying endoscopy with narrow-band imaging for determining the horizontal extent of early gastric cancer when there is an unclear margin by chromoendoscopy (with video). Gastrointest Endosc 74:1259–1267PubMedCrossRef
9.
Zurück zum Zitat Kudo S, Kashida H, Nakajima T et al (1997) Endoscopic diagnosis and treatment of early colorectal cancer. World J Surg 21:694–701PubMedCrossRef Kudo S, Kashida H, Nakajima T et al (1997) Endoscopic diagnosis and treatment of early colorectal cancer. World J Surg 21:694–701PubMedCrossRef
10.
Zurück zum Zitat Kudo S, Tamura S, Nakajima T et al (1996) Diagnosis of colorectal tumorous lesions by magnifying endoscopy. Gastrointest Endosc 44:8–14PubMedCrossRef Kudo S, Tamura S, Nakajima T et al (1996) Diagnosis of colorectal tumorous lesions by magnifying endoscopy. Gastrointest Endosc 44:8–14PubMedCrossRef
11.
Zurück zum Zitat Oka S, Tanaka S, Hiyama T et al (2004) Clinicopathologic and endoscopic features of colorectal serrated adenoma: differences between polypoid and superficial types. Gastrointest Endosc 59:213–219PubMedCrossRef Oka S, Tanaka S, Hiyama T et al (2004) Clinicopathologic and endoscopic features of colorectal serrated adenoma: differences between polypoid and superficial types. Gastrointest Endosc 59:213–219PubMedCrossRef
12.
Zurück zum Zitat Hochberger J, Kruse E, Gaertner T et al (2010) Endoskopische Submukosadissektion (ESD) im Ösophagus. Endoskopie heute 23:2–8CrossRef Hochberger J, Kruse E, Gaertner T et al (2010) Endoskopische Submukosadissektion (ESD) im Ösophagus. Endoskopie heute 23:2–8CrossRef
13.
Zurück zum Zitat Wang WL, Wu ZH, Sun Q et al (2012) Meta-analysis: the use of carbon dioxide insufflation vs. room air insufflation for gastrointestinal endoscopy. Aliment Pharmacol Ther 35:1145–1154PubMedCrossRef Wang WL, Wu ZH, Sun Q et al (2012) Meta-analysis: the use of carbon dioxide insufflation vs. room air insufflation for gastrointestinal endoscopy. Aliment Pharmacol Ther 35:1145–1154PubMedCrossRef
14.
Zurück zum Zitat Hochberger J, Kruse E, Wedi E et al (2011) Training in endoscopic mucosal resection and endoscopic submucosal dissection. In: Cohen J (Hrsg) Successful gastrointestinal endoscopy. Wiley-Blackwell, Oxford, UK, S 204–237 Hochberger J, Kruse E, Wedi E et al (2011) Training in endoscopic mucosal resection and endoscopic submucosal dissection. In: Cohen J (Hrsg) Successful gastrointestinal endoscopy. Wiley-Blackwell, Oxford, UK, S 204–237
15.
Zurück zum Zitat Ono S, Fujishiro M, Niimi K et al (2009) Long-term outcomes of endoscopic submucosal dissection for superficial esophageal squamous cell neoplasms. Gastrointest Endosc 70:860–866PubMedCrossRef Ono S, Fujishiro M, Niimi K et al (2009) Long-term outcomes of endoscopic submucosal dissection for superficial esophageal squamous cell neoplasms. Gastrointest Endosc 70:860–866PubMedCrossRef
16.
Zurück zum Zitat Hochberger J, Dammer S, Menke D et al (2010) Technische Aspekte bei der endoskopischen Submucosa-Dissektion (ESD). Endoskopie heute 23:24–33CrossRef Hochberger J, Dammer S, Menke D et al (2010) Technische Aspekte bei der endoskopischen Submucosa-Dissektion (ESD). Endoskopie heute 23:24–33CrossRef
17.
Zurück zum Zitat Hochberger J, Kruse E, Wedi E et al (2011) Neue Instrumente für die endoskopische Submukosadissektion. Gastroenterologe 6:418–426CrossRef Hochberger J, Kruse E, Wedi E et al (2011) Neue Instrumente für die endoskopische Submukosadissektion. Gastroenterologe 6:418–426CrossRef
18.
Zurück zum Zitat Hochberger J (2010) Endoscopic submucosal dissection (ESD) – an educational DVD. 1. Aufl. LUX AV Audiovisual Editions, Kassel Hochberger J (2010) Endoscopic submucosal dissection (ESD) – an educational DVD. 1. Aufl. LUX AV Audiovisual Editions, Kassel
19.
Zurück zum Zitat Robert Koch-Institut, Gesellschaft der epidemiologischen Krebsregister in Deutschland e. V. (Hrsg) B. Krebs in Deutschland 2007/2008. 8. Ausgabe Robert Koch-Institut, Gesellschaft der epidemiologischen Krebsregister in Deutschland e. V. (Hrsg) B. Krebs in Deutschland 2007/2008. 8. Ausgabe
20.
Zurück zum Zitat Parkin DM, Bray F, Ferlay J et al (2002) Global cancer statistics. CA Cancer J Clin 55:74–108CrossRef Parkin DM, Bray F, Ferlay J et al (2002) Global cancer statistics. CA Cancer J Clin 55:74–108CrossRef
21.
Zurück zum Zitat Sano T, Kobori O, Muto T (1992) Lymph node metastasis from early gastric cancer: endoscopic resection of tumour. Br J Surg 79:241–244PubMedCrossRef Sano T, Kobori O, Muto T (1992) Lymph node metastasis from early gastric cancer: endoscopic resection of tumour. Br J Surg 79:241–244PubMedCrossRef
22.
Zurück zum Zitat Amano Y, Ishihara S, Amano K et al (1998) An assessment of local curability of endoscopic surgery in early gastric cancer without satisfaction of current therapeutic indications. Endoscopy 30:548–552PubMedCrossRef Amano Y, Ishihara S, Amano K et al (1998) An assessment of local curability of endoscopic surgery in early gastric cancer without satisfaction of current therapeutic indications. Endoscopy 30:548–552PubMedCrossRef
23.
Zurück zum Zitat Gotoda T, Sasako M, Ono H et al (2001) Evaluation of the necessity for gastrectomy with lymph node dissection for patients with submucosal invasive gastric cancer. Br J Surg 88:444–449PubMedCrossRef Gotoda T, Sasako M, Ono H et al (2001) Evaluation of the necessity for gastrectomy with lymph node dissection for patients with submucosal invasive gastric cancer. Br J Surg 88:444–449PubMedCrossRef
24.
Zurück zum Zitat Gotoda T, Yanagisawa A, Sasako M et al (2000) Incidence of lymph node metastasis from early gastric cancer: estimation with a large number of cases at two large centers. Gastric Cancer 3:219–225PubMedCrossRef Gotoda T, Yanagisawa A, Sasako M et al (2000) Incidence of lymph node metastasis from early gastric cancer: estimation with a large number of cases at two large centers. Gastric Cancer 3:219–225PubMedCrossRef
25.
Zurück zum Zitat Hosokawa K, Yoshida S (1998) Recent advances in endoscopic mucosal resection for early gastric cancer. Gan To Kagaku Ryoho 25:476–483PubMed Hosokawa K, Yoshida S (1998) Recent advances in endoscopic mucosal resection for early gastric cancer. Gan To Kagaku Ryoho 25:476–483PubMed
26.
Zurück zum Zitat Ono H, Kondo H, Gotoda T et al (2001) Endoscopic mucosal resection for treatment of early gastric cancer. Gut 48:225–229PubMedCrossRef Ono H, Kondo H, Gotoda T et al (2001) Endoscopic mucosal resection for treatment of early gastric cancer. Gut 48:225–229PubMedCrossRef
27.
Zurück zum Zitat Ohkuwa M, Hosokawa K, Boku N et al (2001) New endoscopic treatment for intramucosal gastric tumors using an insulated-tip diathermic knife. Endoscopy 33:221–226PubMedCrossRef Ohkuwa M, Hosokawa K, Boku N et al (2001) New endoscopic treatment for intramucosal gastric tumors using an insulated-tip diathermic knife. Endoscopy 33:221–226PubMedCrossRef
28.
Zurück zum Zitat Miyamoto S, Muto M, Hamamoto Y et al (2002) A new technique for endoscopic mucosal resection with an insulated-tip electrosurgical knife improves the completeness of resection of intramucosal gastric neoplasms. Gastrointest Endosc 55:576–581PubMedCrossRef Miyamoto S, Muto M, Hamamoto Y et al (2002) A new technique for endoscopic mucosal resection with an insulated-tip electrosurgical knife improves the completeness of resection of intramucosal gastric neoplasms. Gastrointest Endosc 55:576–581PubMedCrossRef
29.
Zurück zum Zitat Lian J, Chen S, Zhang Y et al (2012) A meta-analysis of endoscopic submucosal dissection and EMR for early gastric cancer. Gastrointest Endosc 76:763–770PubMedCrossRef Lian J, Chen S, Zhang Y et al (2012) A meta-analysis of endoscopic submucosal dissection and EMR for early gastric cancer. Gastrointest Endosc 76:763–770PubMedCrossRef
30.
Zurück zum Zitat Oda I, Saito D, Tada M et al (2006) A multicenter retrospective study of endoscopic resection for early gastric cancer. Gastric Cancer 9:262–270PubMedCrossRef Oda I, Saito D, Tada M et al (2006) A multicenter retrospective study of endoscopic resection for early gastric cancer. Gastric Cancer 9:262–270PubMedCrossRef
31.
Zurück zum Zitat Probst A, Pommer B, Golger D et al (2010) Endoscopic submucosal dissection in gastric neoplasia – experience from a European center. Endoscopy 42:1037–1044PubMedCrossRef Probst A, Pommer B, Golger D et al (2010) Endoscopic submucosal dissection in gastric neoplasia – experience from a European center. Endoscopy 42:1037–1044PubMedCrossRef
32.
Zurück zum Zitat Association JGC (1998) Japanese classification of gastric carcinoma – second English edition. Gastric Cancer 1:10–24CrossRef Association JGC (1998) Japanese classification of gastric carcinoma – second English edition. Gastric Cancer 1:10–24CrossRef
33.
Zurück zum Zitat Schumacher B, Charton JP, Nordmann T et al (2012) Endoscopic submucosal dissection of early gastric neoplasia with a water jet-assisted knife: a Western, single-center experience. Gastrointest Endosc 75:1166–1174PubMedCrossRef Schumacher B, Charton JP, Nordmann T et al (2012) Endoscopic submucosal dissection of early gastric neoplasia with a water jet-assisted knife: a Western, single-center experience. Gastrointest Endosc 75:1166–1174PubMedCrossRef
34.
Zurück zum Zitat Saito Y, Emura F, Matsuda T et al (2005) A new sinker-assisted endoscopic submucosal dissection for colorectal cancer. Gastrointest Endosc 62:297–301PubMedCrossRef Saito Y, Emura F, Matsuda T et al (2005) A new sinker-assisted endoscopic submucosal dissection for colorectal cancer. Gastrointest Endosc 62:297–301PubMedCrossRef
35.
Zurück zum Zitat Fujishiro M, Yahagi N, Nakamura M et al (2006) Endoscopic submucosal dissection for rectal epithelial neoplasia. Endoscopy 38:493–497PubMedCrossRef Fujishiro M, Yahagi N, Nakamura M et al (2006) Endoscopic submucosal dissection for rectal epithelial neoplasia. Endoscopy 38:493–497PubMedCrossRef
36.
Zurück zum Zitat Fujishiro M, Yahagi N, Kakushima N et al (2007) Outcomes of endoscopic submucosal dissection for colorectal epithelial neoplasms in 200 consecutive cases. Clin Gastroenterol Hepatol 5:678–683PubMedCrossRef Fujishiro M, Yahagi N, Kakushima N et al (2007) Outcomes of endoscopic submucosal dissection for colorectal epithelial neoplasms in 200 consecutive cases. Clin Gastroenterol Hepatol 5:678–683PubMedCrossRef
37.
Zurück zum Zitat Hurlstone DP, Atkinson R, Sanders DS et al (2007) Achieving R0 resection in the colorectum using endoscopic submucosal dissection. Br J Surg 94:1536–1542PubMedCrossRef Hurlstone DP, Atkinson R, Sanders DS et al (2007) Achieving R0 resection in the colorectum using endoscopic submucosal dissection. Br J Surg 94:1536–1542PubMedCrossRef
38.
Zurück zum Zitat Repici A, Hassan C, De Paula Pessoa D et al (2012) Efficacy and safety of endoscopic submucosal dissection for colorectal neoplasia: a systematic review. Endoscopy 44:137–150PubMedCrossRef Repici A, Hassan C, De Paula Pessoa D et al (2012) Efficacy and safety of endoscopic submucosal dissection for colorectal neoplasia: a systematic review. Endoscopy 44:137–150PubMedCrossRef
39.
Zurück zum Zitat Probst A, Golger D, Arnholdt H et al (2009) Endoscopic submucosal dissection of early cancers, flat adenomas, and submucosal tumors in the gastrointestinal tract. Clin Gastroenterol Hepatol 7:149–155PubMedCrossRef Probst A, Golger D, Arnholdt H et al (2009) Endoscopic submucosal dissection of early cancers, flat adenomas, and submucosal tumors in the gastrointestinal tract. Clin Gastroenterol Hepatol 7:149–155PubMedCrossRef
40.
Zurück zum Zitat Probst A, Golger D, Anthuber M et al (2012) Endoscopic submucosal dissection in large sessile lesions of the rectosigmoid: learning curve in a European center. Endoscopy 44:660–667PubMedCrossRef Probst A, Golger D, Anthuber M et al (2012) Endoscopic submucosal dissection in large sessile lesions of the rectosigmoid: learning curve in a European center. Endoscopy 44:660–667PubMedCrossRef
41.
Zurück zum Zitat Kruse E, Buerrig KF, Wilhelms G et al (2012) Endoskopische Submucosa Dissektionen (ESD) bei 81 Patienten mit flächigen Polypen im Recto-Sigmoid bis 16 cm Größe. Endoskopie heute 25:FV7 (Abstract) Kruse E, Buerrig KF, Wilhelms G et al (2012) Endoskopische Submucosa Dissektionen (ESD) bei 81 Patienten mit flächigen Polypen im Recto-Sigmoid bis 16 cm Größe. Endoskopie heute 25:FV7 (Abstract)
42.
Zurück zum Zitat Titi M, Overhiser A, Ulusarac O et al (2012) Development of subsquamous high-grade dysplasia and adenocarcinoma after successful radiofrequency ablation of Barrett’s esophagus. Gastroenterology 143:564–566.e1PubMedCrossRef Titi M, Overhiser A, Ulusarac O et al (2012) Development of subsquamous high-grade dysplasia and adenocarcinoma after successful radiofrequency ablation of Barrett’s esophagus. Gastroenterology 143:564–566.e1PubMedCrossRef
43.
Zurück zum Zitat Hochberger J, Koehler P, Wedi E et al (2012) Successful mucosal transplantation from stomach to esophagus for stricture prevention after widespread circular endoscopic submucosal dissection (ESD) for early esophageal squamous cell carcinoma – report of a first case in man with 1 year transplant survival after preliminary experiments in the pig. Z Gastroenterol 50:108 (Abstract K261) Hochberger J, Koehler P, Wedi E et al (2012) Successful mucosal transplantation from stomach to esophagus for stricture prevention after widespread circular endoscopic submucosal dissection (ESD) for early esophageal squamous cell carcinoma – report of a first case in man with 1 year transplant survival after preliminary experiments in the pig. Z Gastroenterol 50:108 (Abstract K261)
44.
Zurück zum Zitat Mori H, Rafiq K, Kobara H et al (2012) Local steroid injection into the artificial ulcer created by endoscopic submucosal dissection for gastric cancer: prevention of gastric deformity. Endoscopy 44:641–648PubMedCrossRef Mori H, Rafiq K, Kobara H et al (2012) Local steroid injection into the artificial ulcer created by endoscopic submucosal dissection for gastric cancer: prevention of gastric deformity. Endoscopy 44:641–648PubMedCrossRef
45.
Zurück zum Zitat Hanaoka N, Ishihara R, Takeuchi Y et al (2012) Intralesional steroid injection to prevent stricture after endoscopic submucosal dissection for esophageal cancer: a controlled prospective study. Endoscopy 44:1007–1011PubMedCrossRef Hanaoka N, Ishihara R, Takeuchi Y et al (2012) Intralesional steroid injection to prevent stricture after endoscopic submucosal dissection for esophageal cancer: a controlled prospective study. Endoscopy 44:1007–1011PubMedCrossRef
46.
Zurück zum Zitat Isomoto H, Yamaguchi N, Nakayama T et al (2011) Management of esophageal stricture after complete circular endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma. BMC Gastroenterol 11:46PubMedCrossRef Isomoto H, Yamaguchi N, Nakayama T et al (2011) Management of esophageal stricture after complete circular endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma. BMC Gastroenterol 11:46PubMedCrossRef
47.
Zurück zum Zitat Yamaguchi N, Isomoto H, Shikuwa S et al (2011) Effect of oral prednisolone on esophageal stricture after complete circular endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma: a case report. Digestion 83:291–295PubMedCrossRef Yamaguchi N, Isomoto H, Shikuwa S et al (2011) Effect of oral prednisolone on esophageal stricture after complete circular endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma: a case report. Digestion 83:291–295PubMedCrossRef
48.
Zurück zum Zitat Yamaguchi N, Isomoto H, Nakayama T et al (2011) Usefulness of oral prednisolone in the treatment of esophageal stricture after endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma. Gastrointest Endosc 73:1115–1121PubMedCrossRef Yamaguchi N, Isomoto H, Nakayama T et al (2011) Usefulness of oral prednisolone in the treatment of esophageal stricture after endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma. Gastrointest Endosc 73:1115–1121PubMedCrossRef
49.
Zurück zum Zitat Wedi E, Menke D, Hochberger J (2012) Der Over-The-Scope-Clip (OTSC) – Erste klinische Erfahrung bei der Behandlung von schweren Blutungen, Perforationen und Fisteln an 40 Patienten. Endoskopie heute 25:FV24 (Abstract)CrossRef Wedi E, Menke D, Hochberger J (2012) Der Over-The-Scope-Clip (OTSC) – Erste klinische Erfahrung bei der Behandlung von schweren Blutungen, Perforationen und Fisteln an 40 Patienten. Endoskopie heute 25:FV24 (Abstract)CrossRef
50.
Zurück zum Zitat Zhang XL, Qu JH, Sun G et al (2012) Feasibility study of secure closure of gastric fundus perforation using over-the-scope clips in a dog model. J Gastroenterol Hepatol 27:1200–1204 Zhang XL, Qu JH, Sun G et al (2012) Feasibility study of secure closure of gastric fundus perforation using over-the-scope clips in a dog model. J Gastroenterol Hepatol 27:1200–1204
51.
Zurück zum Zitat Renteln D von, Rosch T, Kratt T et al (2012) Endoscopic full-thickness resection of submucosal gastric tumors. Dig Dis Sci 57:1298–1303CrossRef Renteln D von, Rosch T, Kratt T et al (2012) Endoscopic full-thickness resection of submucosal gastric tumors. Dig Dis Sci 57:1298–1303CrossRef
52.
Zurück zum Zitat Topazian M, Zhong N, Baron TH et al (2012) Photodynamic therapy of intraductal papillary mucinous neoplasm. Endoscopy 44:213–215PubMedCrossRef Topazian M, Zhong N, Baron TH et al (2012) Photodynamic therapy of intraductal papillary mucinous neoplasm. Endoscopy 44:213–215PubMedCrossRef
53.
Zurück zum Zitat Suhail AH, Marvik R, Halgunset J et al (2012) Efficacy and safety of transgastric closure in natural orifice transluminal endoscopic surgery using the OTSC system and T-bar sutures: a survival study in a porcine model. Surg Endosc 26:2950–2954PubMedCrossRef Suhail AH, Marvik R, Halgunset J et al (2012) Efficacy and safety of transgastric closure in natural orifice transluminal endoscopic surgery using the OTSC system and T-bar sutures: a survival study in a porcine model. Surg Endosc 26:2950–2954PubMedCrossRef
54.
Zurück zum Zitat Yoshida N, Yagi N, Inada Y et al (2012) Possibility of ex vivo animal training model for colorectal endoscopic submucosal dissection. Int J Colorectal Dis 28:49–56PubMedCrossRef Yoshida N, Yagi N, Inada Y et al (2012) Possibility of ex vivo animal training model for colorectal endoscopic submucosal dissection. Int J Colorectal Dis 28:49–56PubMedCrossRef
55.
Zurück zum Zitat Yamamoto Y, Fujisaki J, Ishiyama A et al (2012) Current status of training for endoscopic submucosal dissection for gastric epithelial neoplasm at Cancer Institute Hospital, Japanese Foundation for Cancer Research, a famous Japanese hospital. Dig Endosc 24(Suppl 1):148–153PubMedCrossRef Yamamoto Y, Fujisaki J, Ishiyama A et al (2012) Current status of training for endoscopic submucosal dissection for gastric epithelial neoplasm at Cancer Institute Hospital, Japanese Foundation for Cancer Research, a famous Japanese hospital. Dig Endosc 24(Suppl 1):148–153PubMedCrossRef
56.
Zurück zum Zitat Tanaka S, Morita Y, Fujita T et al (2012) Ex vivo pig training model for esophageal endoscopic submucosal dissection (ESD) for endoscopists with experience in gastric ESD. Surg Endosc 26:1579–1586PubMedCrossRef Tanaka S, Morita Y, Fujita T et al (2012) Ex vivo pig training model for esophageal endoscopic submucosal dissection (ESD) for endoscopists with experience in gastric ESD. Surg Endosc 26:1579–1586PubMedCrossRef
57.
Zurück zum Zitat Ohata K, Ito T, Chiba H et al (2012) Effective training system in colorectal endoscopic submucosal dissection. Dig Endosc 24(Suppl 1):84–89PubMedCrossRef Ohata K, Ito T, Chiba H et al (2012) Effective training system in colorectal endoscopic submucosal dissection. Dig Endosc 24(Suppl 1):84–89PubMedCrossRef
58.
Zurück zum Zitat Oda I, Odagaki T, Suzuki H et al (2012) Learning curve for endoscopic submucosal dissection of early gastric cancer based on trainee experience. Dig Endosc 24(Suppl 1):129–132PubMedCrossRef Oda I, Odagaki T, Suzuki H et al (2012) Learning curve for endoscopic submucosal dissection of early gastric cancer based on trainee experience. Dig Endosc 24(Suppl 1):129–132PubMedCrossRef
59.
Zurück zum Zitat Niimi K, Fujishiro M, Goto O et al (2012) Safety and efficacy of colorectal endoscopic submucosal dissection by the trainee endoscopists. Dig Endosc 24(Suppl 1):154–158PubMedCrossRef Niimi K, Fujishiro M, Goto O et al (2012) Safety and efficacy of colorectal endoscopic submucosal dissection by the trainee endoscopists. Dig Endosc 24(Suppl 1):154–158PubMedCrossRef
60.
Zurück zum Zitat Kato M, Gromski M, Jung Y et al (2012) The learning curve for endoscopic submucosal dissection in an established experimental setting. Surg Endosc 27:154–161PubMedCrossRef Kato M, Gromski M, Jung Y et al (2012) The learning curve for endoscopic submucosal dissection in an established experimental setting. Surg Endosc 27:154–161PubMedCrossRef
61.
Zurück zum Zitat Tanimoto MA, Torres-Villalobos G, Fujita R et al (2011) Learning curve in a Western training center of the circumferential en bloc esophageal endoscopic submucosal dissection in an in vivo animal model. Diagn Ther Endosc 2011:847831PubMedCrossRef Tanimoto MA, Torres-Villalobos G, Fujita R et al (2011) Learning curve in a Western training center of the circumferential en bloc esophageal endoscopic submucosal dissection in an in vivo animal model. Diagn Ther Endosc 2011:847831PubMedCrossRef
62.
Zurück zum Zitat Takahashi T, Ando T, Kabeshima Y et al (2009) Borderline cases between benignancy and malignancy of the duodenum diagnosed successfully by endoscopic submucosal dissection. Scand J Gastroenterol 44:1377–1383PubMedCrossRef Takahashi T, Ando T, Kabeshima Y et al (2009) Borderline cases between benignancy and malignancy of the duodenum diagnosed successfully by endoscopic submucosal dissection. Scand J Gastroenterol 44:1377–1383PubMedCrossRef
63.
Zurück zum Zitat Honda T, Yamamoto H, Osawa H et al (2009) Endoscopic submucosal dissection for superficial duodenal neoplasms. Dig Endosc 21:270–274PubMedCrossRef Honda T, Yamamoto H, Osawa H et al (2009) Endoscopic submucosal dissection for superficial duodenal neoplasms. Dig Endosc 21:270–274PubMedCrossRef
64.
Zurück zum Zitat Muguruma N, Okamura S, Imoto Y et al (2012) Hypopharyngeal injury caused by overtube insertion during endoscopic submucosal dissection. Endoscopy 44(Suppl 2) UCTN:E225PubMedCrossRef Muguruma N, Okamura S, Imoto Y et al (2012) Hypopharyngeal injury caused by overtube insertion during endoscopic submucosal dissection. Endoscopy 44(Suppl 2) UCTN:E225PubMedCrossRef
65.
Zurück zum Zitat Iizuka T, Kikuchi D, Hoteya S et al (2011) Clinical advantage of endoscopic submucosal dissection over endoscopic mucosal resection for early mesopharyngeal and hypopharyngeal cancers. Endoscopy 43:839–843PubMedCrossRef Iizuka T, Kikuchi D, Hoteya S et al (2011) Clinical advantage of endoscopic submucosal dissection over endoscopic mucosal resection for early mesopharyngeal and hypopharyngeal cancers. Endoscopy 43:839–843PubMedCrossRef
66.
Zurück zum Zitat Shimizu Y, Yamamoto J, Kato M et al (2006) Endoscopic submucosal dissection for treatment of early stage hypopharyngeal carcinoma. Gastrointest Endosc 64:255–259 (Diskussion: 260–262) Shimizu Y, Yamamoto J, Kato M et al (2006) Endoscopic submucosal dissection for treatment of early stage hypopharyngeal carcinoma. Gastrointest Endosc 64:255–259 (Diskussion: 260–262)
67.
Zurück zum Zitat Inoue H, Minami H, Kobayashi Y et al (2010) Peroral endoscopic myotomy (POEM) for esophageal achalasia. Endoscopy 42:265–271PubMedCrossRef Inoue H, Minami H, Kobayashi Y et al (2010) Peroral endoscopic myotomy (POEM) for esophageal achalasia. Endoscopy 42:265–271PubMedCrossRef
68.
Zurück zum Zitat Renteln D von, Inoue H, Minami H et al (2012) Peroral endoscopic myotomy for the treatment of achalasia: a prospective single center study. Am J Gastroenterol 107:411–417CrossRef Renteln D von, Inoue H, Minami H et al (2012) Peroral endoscopic myotomy for the treatment of achalasia: a prospective single center study. Am J Gastroenterol 107:411–417CrossRef
69.
Zurück zum Zitat Hochberger J, Kruse E, Wedi E et al (2011) Neue Instrumente für die endoskopische Submukosadissektion. Endo-Praxis 27:150–156 Hochberger J, Kruse E, Wedi E et al (2011) Neue Instrumente für die endoskopische Submukosadissektion. Endo-Praxis 27:150–156
70.
Zurück zum Zitat Kaltenbach T, Soetikno R (2013) Endoscopic resection of large colon polyps. Gastrointest Endosc Clin N Am 23:137–152PubMedCrossRef Kaltenbach T, Soetikno R (2013) Endoscopic resection of large colon polyps. Gastrointest Endosc Clin N Am 23:137–152PubMedCrossRef
71.
Zurück zum Zitat Gostout CJ, Knipschield MA (2012) Submucosal endoscopy with mucosal resection: a hybrid endoscopic submucosal dissection in the porcine rectum and distal colon. Gastrointest Endosc 76:829–834PubMedCrossRef Gostout CJ, Knipschield MA (2012) Submucosal endoscopy with mucosal resection: a hybrid endoscopic submucosal dissection in the porcine rectum and distal colon. Gastrointest Endosc 76:829–834PubMedCrossRef
72.
Zurück zum Zitat Sumiyama K, Tajiri H, Gostout CJ et al (2010) Chemically assisted submucosal injection facilitates endoscopic submucosal dissection of gastric neoplasms. Endoscopy 42:627–632PubMedCrossRef Sumiyama K, Tajiri H, Gostout CJ et al (2010) Chemically assisted submucosal injection facilitates endoscopic submucosal dissection of gastric neoplasms. Endoscopy 42:627–632PubMedCrossRef
73.
Zurück zum Zitat Sumiyama K, Gostout CJ (2007) Novel techniques and instrumentation for EMR, ESD, and full-thickness endoscopic luminal resection. Gastrointest Endosc Clin N Am 17:471–485, v–viPubMedCrossRef Sumiyama K, Gostout CJ (2007) Novel techniques and instrumentation for EMR, ESD, and full-thickness endoscopic luminal resection. Gastrointest Endosc Clin N Am 17:471–485, v–viPubMedCrossRef
74.
Zurück zum Zitat Uraoka T, Saito Y, Yahagi N (2012) What are the latest developments in colorectal endoscopic submucosal dissection? World J Gastrointest Endosc 4:296–300PubMedCrossRef Uraoka T, Saito Y, Yahagi N (2012) What are the latest developments in colorectal endoscopic submucosal dissection? World J Gastrointest Endosc 4:296–300PubMedCrossRef
Metadaten
Titel
Endoskopische Submukosadissektion
verfasst von
Prof. Dr. J. Hochberger
P. Köhler
E. Kruse
J. Hûppertz
M. Delvaux
G. Gay
E. Wedi
Publikationsdatum
01.03.2013
Verlag
Springer-Verlag
Erschienen in
Die Innere Medizin / Ausgabe 3/2013
Print ISSN: 2731-7080
Elektronische ISSN: 2731-7099
DOI
https://doi.org/10.1007/s00108-012-3179-2

Weitere Artikel der Ausgabe 3/2013

Der Internist 3/2013 Zur Ausgabe

CME Zertifizierte Fortbildung

Hyperthyreose

Mitteilungen des BDI

Mitteilungen

Medizin aktuell

J-Kurve

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.