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Erschienen in: Die Urologie 12/2008

01.12.2008 | Übersichten

Testikuläre adrenale Resttumoren (TART) bei erwachsenen Männern mit klassischem adrenogenitalen Syndrom (AGS)

verfasst von: P. Knape, N. Reisch, H.-G. Dörr, M. Reincke, S. Lenk, M. Quinkler

Erschienen in: Die Urologie | Ausgabe 12/2008

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Zusammenfassung

Hintergrund

Über die Behandlung von männlichen erwachsenen Patienten mit adrenogenitalem Syndrom (AGS) und testikulären adrenalen Resttumoren (TART) liegen wenige Informationen vor. Ein direktes Therapieschema existiert bisher nicht, und daher ist es Ziel dieser Übersichtsarbeit, den gegenwärtigen Stand der Therapiekonzepte darzustellen.

Methoden

Es wurde eine ausführliche Literaturrecherche mittels Pubmed/Medline mit Schwerpunkt auf die letzten 10 Jahre durchgeführt.

Ergebnisse

Die Ziele in der Behandlung erwachsener Patienten mit AGS sind v. a. Fertilitätssicherung, Prävention von Addison-Krisen, Verhinderung von TART, Wohlbefinden, gute Lebensqualität, befriedigende Sexualfunktion und natürlich die Prävention von iatrogenen Langzeitfolgen von Glukokortikoid- und Mineralokortikoiddauertherapie. Dennoch ist die Fertilität von AGS-Patienten signifikant verringert und mit dem Auftreten von TART korreliert. Die derzeit existierenden Therapieoptionen werden diskutiert.

Schlussfolgerungen

Ein zukünftiges System regelmäßiger Folgeuntersuchungen und ein standardisiertes Therapieregime sind notwendig, um eine bessere Fertilität und Langzeitlebensqualität für die Patienten zu erreichen.
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Metadaten
Titel
Testikuläre adrenale Resttumoren (TART) bei erwachsenen Männern mit klassischem adrenogenitalen Syndrom (AGS)
verfasst von
P. Knape
N. Reisch
H.-G. Dörr
M. Reincke
S. Lenk
M. Quinkler
Publikationsdatum
01.12.2008
Verlag
Springer-Verlag
Erschienen in
Die Urologie / Ausgabe 12/2008
Print ISSN: 2731-7064
Elektronische ISSN: 2731-7072
DOI
https://doi.org/10.1007/s00120-008-1857-4

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