nach oben

Diabetologia

Erschienen in:

01.11.2009 | Meta-analysis

Meat consumption and the risk of type 2 diabetes: a systematic review and meta-analysis of cohort studies

verfasst von: D. Aune, G. Ursin, M. B. Veierød

Erschienen in: Diabetologia | Ausgabe 11/2009

Einloggen, um Zugang zu erhalten

Abstract

Aims/hypothesis

Diet is thought to play an important role in the aetiology of type 2 diabetes. Previous studies have found positive associations between meat consumption and the risk of type 2 diabetes, but the results have been inconsistent. We conducted a systematic review and meta-analysis of cohort studies of meat consumption and type 2 diabetes risk.

Methods

We searched several databases for cohort studies on meat consumption and type 2 diabetes risk, up to December 2008. Summary relative risks were estimated by use of a random-effects model.

Results

We identified 12 cohort studies. The estimated summary RR and 95% confidence interval of type 2 diabetes comparing high vs low intake was 1.17 (95% CI 0.92–1.48) for total meat, 1.21 (95% CI 1.07–1.38) for red meat and 1.41 (95% CI 1.25–1.60) for processed meat. There was heterogeneity amongst the studies of total, red and processed meat which, to some degree, was explained by the study characteristics.

Conclusions/interpretation

These results suggest that meat consumption increases the risk of type 2 diabetes. However, the possibility that residual confounding could explain this association cannot be excluded.

Wild S, Roglic G, Green A, Sicree R, King H (2004) Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 27:1047–1053CrossRefPubMed

Anonymous (2006) Standards of medical care in diabetes—2006. Diabetes Care 29(Suppl 1):S4–S42

Anonymous (2008) Economic costs of diabetes in the U.S. in 2007. Diabetes Care 31:596–615

Rana JS, Li TY, Manson JE, Hu FB (2007) Adiposity compared with physical inactivity and risk of type 2 diabetes in women. Diabetes Care 30:53–58CrossRefPubMed

Tuomilehto J, Lindstrom J, Eriksson JG et al (2001) Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 344:1343–1350CrossRefPubMed

Himsworth HP (1935) Diet and the incidence of diabetes mellitus. Clin Sci 1:117–148

Kawate R, Yamakido M, Nishimoto Y, Bennett PH, Hamman RF, Knowler WC (1979) Diabetes mellitus and its vascular complications in Japanese migrants on the Island of Hawaii. Diabetes Care 2:161–170CrossRefPubMed

Misra A, Ganda OP (2007) Migration and its impact on adiposity and type 2 diabetes. Nutrition 23:696–708CrossRefPubMed

Kitagawa T, Owada M, Urakami T, Yamauchi K (1998) Increased incidence of non-insulin dependent diabetes mellitus among Japanese schoolchildren correlates with an increased intake of animal protein and fat. Clin Pediatr (Phila) 37:111–115CrossRef

10.

Wang Y, Mi J, Shan XY, Wang QJ, Ge KY (2007) Is China facing an obesity epidemic and the consequences? The trends in obesity and chronic disease in China. Int J Obes (Lond) 31:177–188CrossRef

11.

Cheng Y, Chen KJ, Wang CJ, Chan SH, Chang WC, Chen JH (2005) Secular trends in coronary heart disease mortality, hospitalization rates, and major cardiovascular risk factors in Taiwan, 1971–2001. Int J Cardiol 100:47–52CrossRefPubMed

12.

Choi YJ, Cho YM, Park CK et al (2006) Rapidly increasing diabetes-related mortality with socio-environmental changes in South Korea during the last two decades. Diabetes Res Clin Pract 74:295–300CrossRefPubMed

13.

Schulze MB, Hoffmann K, Manson JE et al (2005) Dietary pattern, inflammation, and incidence of type 2 diabetes in women. Am J Clin Nutr 82:675–684PubMed

14.

van Dam RM, Rimm EB, Willett WC, Stampfer MJ, Hu FB (2002) Dietary patterns and risk for type 2 diabetes mellitus in U.S. men. Ann Intern Med 136:201–209PubMed

15.

Hodge AM, English DR, O'Dea K, Giles GG (2007) Dietary patterns and diabetes incidence in the Melbourne Collaborative Cohort Study. Am J Epidemiol 165:603–610CrossRefPubMed

16.

Snowdon DA, Phillips RL (1985) Does a vegetarian diet reduce the occurrence of diabetes? Am J Public Health 75:507–512CrossRefPubMed

17.

Fung TT, Schulze M, Manson JE, Willett WC, Hu FB (2004) Dietary patterns, meat intake, and the risk of type 2 diabetes in women. Arch Intern Med 164:2235–2240CrossRefPubMed

18.

Schulze MB, Manson JE, Willett WC, Hu FB (2003) Processed meat intake and incidence of Type 2 diabetes in younger and middle-aged women. Diabetologia 46:1465–1473CrossRefPubMed

19.

Song Y, Manson JE, Buring JE, Liu S (2004) A prospective study of red meat consumption and type 2 diabetes in middle-aged and elderly women: the women's health study. Diabetes Care 27:2108–2115CrossRefPubMed

20.

van Dam RM, Willett WC, Rimm EB, Stampfer MJ, Hu FB (2002) Dietary fat and meat intake in relation to risk of type 2 diabetes in men. Diabetes Care 25:417–424CrossRefPubMed

21.

Villegas R, Shu XO, Gao YT et al (2006) The association of meat intake and the risk of type 2 diabetes may be modified by body weight. Int J Med Sci 3:152–159PubMed

22.

Simmons RK, Harding AH, Wareham NJ, Griffin SJ (2007) Do simple questions about diet and physical activity help to identify those at risk of type 2 diabetes? Diabet Med 24:830–835CrossRefPubMed

23.

Vang A, Singh PN, Lee JW, Haddad EH, Brinegar CH (2008) Meats, processed meats, obesity, weight gain and occurrence of diabetes among adults: findings from adventist health studies. Ann Nutr Metab 52:96–104CrossRefPubMed

24.

Lee DH, Folsom AR, Jacobs DR Jr (2004) Dietary iron intake and Type 2 diabetes incidence in postmenopausal women: the Iowa Women's Health Study. Diabetologia 47:185–194CrossRefPubMed

25.

Schulze MB, Hoffmann K, Boeing H et al (2007) An accurate risk score based on anthropometric, dietary, and lifestyle factors to predict the development of type 2 diabetes. Diabetes Care 30:510–515CrossRefPubMed

26.

Hirayama T (1990) Life-style and mortality: a large-scale census-based cohort study in Japan. Karger, Basel

27.

Montonen J, Jarvinen R, Heliovaara M, Reunanen A, Aromaa A, Knekt P (2005) Food consumption and the incidence of type II diabetes mellitus. Eur J Clin Nutr 59:441–448CrossRefPubMed

28.

DerSimonian R, Laird N (1986) Meta-analysis in clinical trials. Control Clin Trials 7:177–188CrossRefPubMed

29.

Greenland S, Longnecker MP (1992) Methods for trend estimation from summarized dose-response data, with applications to meta-analysis. Am J Epidemiol 135:1301–1309PubMed

30.

Orsini N, Bellocco R, Greenland S (2006) Generalized least squares for trend estimation of summarized dose-response data. Stata Journal 6:40–57

31.

Norat T, Lukanova A, Ferrari P, Riboli E (2002) Meat consumption and colorectal cancer risk: dose-response meta-analysis of epidemiological studies. Int J Cancer 98:241–256CrossRefPubMed

32.

Higgins JP, Thompson SG (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21:1539–1558CrossRefPubMed

33.

Egger M, Davey SG, Schneider M, Minder C (1997) Bias in meta-analysis detected by a simple, graphical test. BMJ 315:629–634PubMed

34.

Begg CB, Mazumdar M (1994) Operating characteristics of a rank correlation test for publication bias. Biometrics 50:1088–1101CrossRefPubMed

35.

Hartemink N, Boshuizen HC, Nagelkerke NJ, Jacobs MA, van Houwelingen HC (2006) Combining risk estimates from observational studies with different exposure cutpoints: a meta-analysis on body mass index and diabetes type 2. Am J Epidemiol 163:1042–1052CrossRefPubMed

36.

Rimm EB, Stampfer MJ, Colditz GA, Chute CG, Litin LB, Willett WC (1990) Validity of self-reported waist and hip circumferences in men and women. Epidemiology 1:466–473CrossRefPubMed

37.

Kushi LH, Kaye SA, Folsom AR, Soler JT, Prineas RJ (1988) Accuracy and reliability of self-measurement of body girths. Am J Epidemiol 128:740–748PubMed

38.

Kipnis V, Subar AF, Midthune D et al (2003) Structure of dietary measurement error: results of the OPEN biomarker study. Am J Epidemiol 158:14–21CrossRefPubMed

39.

Rajpathak S, Ma J, Manson J, Willett WC, Hu FB (2006) Iron intake and the risk of type 2 diabetes in women: a prospective cohort study. Diabetes Care 29:1370–1376CrossRefPubMed

40.

Rothman KJ, Greenland S (1998) Modern epidemiology, 2nd edn. Lippincott Williams & Wilkins, Philadelphia

41.

French SA, Jeffery RW, Forster JL, McGovern PG, Kelder SH, Baxter JE (1994) Predictors of weight change over two years among a population of working adults: the Healthy Worker Project. Int J Obes Relat Metab Disord 18:145–154PubMed

42.

Kahn HS, Tatham LM, Heath CW Jr (1997) Contrasting factors associated with abdominal and peripheral weight gain among adult women. Int J Obes Relat Metab Disord 21:903–911CrossRefPubMed

43.

Schulz M, Kroke A, Liese AD, Hoffmann K, Bergmann MM, Boeing H (2002) Food groups as predictors for short-term weight changes in men and women of the EPIC-Potsdam cohort. J Nutr 132:1335–1340PubMed

44.

Bes-Rastrollo M, Sanchez-Villegas A, Gomez-Gracia E, Martinez JA, Pajares RM, Martinez-Gonzalez MA (2006) Predictors of weight gain in a Mediterranean cohort: the Seguimiento Universidad de Navarra Study 1. Am J Clin Nutr 83:362–370PubMed

45.

Damiao R, Castro TG, Cardoso MA, Gimeno SG, Ferreira SR (2006) Dietary intakes associated with metabolic syndrome in a cohort of Japanese ancestry. Br J Nutr 96:532–538PubMed

46.

Lutsey PL, Steffen LM, Stevens J (2008) Dietary intake and the development of the metabolic syndrome: the atherosclerosis risk in communities study. Circulation 117:754–761CrossRefPubMed

47.

Azadbakht L, Esmaillzadeh A (2009) Red meat intake is associated with metabolic syndrome and the plasma C-reactive protein concentration in women. J Nutr 139:335–339PubMed

48.

Feskens EJ, Virtanen SM, Rasanen L et al (1995) Dietary factors determining diabetes and impaired glucose tolerance. A 20-year follow-up of the Finnish and Dutch cohorts of the Seven Countries Study. Diabetes Care 18:1104–1112CrossRefPubMed

49.

Mayer-Davis EJ, Monaco JH, Hoen HM et al (1997) Dietary fat and insulin sensitivity in a triethnic population: the role of obesity. The Insulin Resistance Atherosclerosis Study (IRAS). Am J Clin Nutr 65:79–87PubMed

50.

Mayer EJ, Newman B, Quesenberry CP Jr, Selby JV (1993) Usual dietary fat intake and insulin concentrations in healthy women twins. Diabetes Care 16:1459–1469CrossRefPubMed

51.

Lundgren H, Bengtsson C, Blohme G et al (1989) Dietary habits and incidence of noninsulin-dependent diabetes mellitus in a population study of women in Gothenburg, Sweden. Am J Clin Nutr 49:708–712PubMed

52.

Meyer KA, Kushi LH, Jacobs DR Jr, Folsom AR (2001) Dietary fat and incidence of type 2 diabetes in older Iowa women. Diabetes Care 24:1528–1535CrossRefPubMed

53.

Jiang R, Ma J, Ascherio A, Stampfer MJ, Willett WC, Hu FB (2004) Dietary iron intake and blood donations in relation to risk of type 2 diabetes in men: a prospective cohort study. Am J Clin Nutr 79:70–75PubMed

54.

Wolff SP (1993) Diabetes mellitus and free radicals. Free radicals, transition metals and oxidative stress in the aetiology of diabetes mellitus and complications. Br Med Bull 49:642–652PubMed

55.

Rajpathak SN, Crandall JP, Wylie-Rosett J, Kabat GC, Rohan TE, Hu FB (2009) The role of iron in type 2 diabetes in humans. Biochim Biophys Acta 1790:671–681PubMed

56.

Papakonstantinou E, Panagiotakos DB, Pitsavos C et al (2005) Food group consumption and glycemic control in people with and without type 2 diabetes: the ATTICA study. Diabetes Care 28:2539–2540CrossRefPubMed

57.

Helgason T, Ewen SW, Ross IS, Stowers JM (1982) Diabetes produced in mice by smoked/cured mutton. Lancet 2:1017–1022CrossRefPubMed

58.

Portha B, Giroix MH, Cros JC, Picon L (1980) Diabetogenic effect of N-nitrosomethylurea and N-nitrosomethylurethane in the adult rat. Ann Nutr Aliment 34:1143–1151PubMed

59.

Ito M, Kondo Y, Nakatani A, Naruse A (1999) New model of progressive non-insulin-dependent diabetes mellitus in mice induced by streptozotocin. Biol Pharm Bull 22:988–989PubMed

60.

Dahlquist GG, Blom LG, Persson LA, Sandstrom AI, Wall SG (1990) Dietary factors and the risk of developing insulin dependent diabetes in childhood. BMJ 300:1302–1306CrossRefPubMed

61.

Sipetic SB, Vlajinac HD, Kocev NI, Marinkovic JM, Radmanovic SZ, Bjekic MD (2005) The Belgrade childhood diabetes study: a multivariate analysis of risk determinants for diabetes. Eur J Public Health 15:117–122CrossRefPubMed

62.

Siemiatycki J, Colle E, Campbell S, Dewar RA, Belmonte MM (1989) Case-control study of IDDM. Diabetes Care 12:209–216CrossRefPubMed

63.

Peppa M, Goldberg T, Cai W, Rayfield E, Vlassara H (2002) Glycotoxins: a missing link in the "relationship of dietary fat and meat intake in relation to risk of type 2 diabetes in men". Diabetes Care 25:1898–1899CrossRefPubMed

64.

Aeberli I, Molinari L, Spinas G, Lehmann R, l'Allemand D, Zimmermann MB (2006) Dietary intakes of fat and antioxidant vitamins are predictors of subclinical inflammation in overweight Swiss children. Am J Clin Nutr 84:748–755PubMed

65.

Lee DH, Steffen LM, Jacobs DR Jr (2004) Association between serum gamma-glutamyltransferase and dietary factors: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Am J Clin Nutr 79:600–605PubMed

66.

Zyriax BC, Algenstaedt P, Hess UF et al (2008) Factors contributing to the risk of cardiovascular disease reflected by plasma adiponectin: data from the coronary risk factors for atherosclerosis in women (CORA) study. Atherosclerosis 200:403–409CrossRefPubMed

67.

Fraser GE (1999) Associations between diet and cancer, ischemic heart disease, and all-cause mortality in non-Hispanic white California Seventh-day Adventists. Am J Clin Nutr 70:532S–538SPubMed

68.

Tonstad S, Butler T, Yan R, Fraser GE (2009) Type of vegetarian diet, body weight, and prevalence of type 2 diabetes. Diabetes Care 32:791–796CrossRefPubMed

Titel: Meat consumption and the risk of type 2 diabetes: a systematic review and meta-analysis of cohort studies
verfasst von: D. Aune
G. Ursin
M. B. Veierød
Publikationsdatum: 01.11.2009
Verlag: Springer-Verlag
Erschienen in: Diabetologia / Ausgabe 11/2009
Print ISSN: 0012-186X
Elektronische ISSN: 1432-0428
DOI: https://doi.org/10.1007/s00125-009-1481-x

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Innere Medizin

23.04.2024 | Ablationstherapie | Nachrichten

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Meat consumption and the risk of type 2 diabetes: a systematic review and meta-analysis of cohort studies

Abstract

Aims/hypothesis

Methods

Results

Conclusions/interpretation

Leitlinien kompakt für die Innere Medizin

Neu im Fachgebiet Innere Medizin

Wie erfolgreich ist eine Re-Ablation nach Rezidiv?

Europäische Ernährungsgewohnheiten: Das sind die häufigsten Fehler

Hinter dieser Appendizitis steckte ein Erreger

Demenzkranke durch Antipsychotika vielfach gefährdet

Update Innere Medizin

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Aims/hypothesis

Methods

Results

Conclusions/interpretation

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 11/2009

Family-based mitochondrial association study of traits related to type 2 diabetes and the metabolic syndrome in adolescents

Contact frequency determines outcome of basal insulin initiation trials in type 2 diabetes

Increased susceptibility to oxidative damage in post-diabetic human myotubes

Central nervous insulin resistance: a promising target in the treatment of metabolic and cognitive disorders?

Use of insulin glargine and cancer incidence in Scotland: a study from the Scottish Diabetes Research Network Epidemiology Group

Association of inflammation with worsening HOMA-insulin resistance

Leitlinien kompakt für die Innere Medizin

Neu im Fachgebiet Innere Medizin

Wie erfolgreich ist eine Re-Ablation nach Rezidiv?

Europäische Ernährungsgewohnheiten: Das sind die häufigsten Fehler

Hinter dieser Appendizitis steckte ein Erreger

Demenzkranke durch Antipsychotika vielfach gefährdet

Update Innere Medizin