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Erschienen in: Diabetologia 9/2011

01.09.2011 | Research Letter

Plasma procalcitonin and risk of type 2 diabetes in the general population

verfasst von: A. Abbasi, E. Corpeleijn, D. Postmus, R. T. Gansevoort, P. E. de Jong, R. O. B. Gans, J. Struck, H. L. Hillege, R. P. Stolk, G. Navis, S. J. L. Bakker

Erschienen in: Diabetologia | Ausgabe 9/2011

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Excerpt

To the Editor: Chronic low-grade inflammation is a key feature of the pathophysiology of obesity, insulin resistance and type 2 diabetes [1]. In vitro studies have found that parenchymal cells of tissues, including adipocytes, secrete procalcitonin in response to stimulation by activated macrophages [2]. Since obesity is associated with an increased presence of activated macrophages in adipose tissue, a similar scenario may play a role in vivo [2, 3]. In an initial study, we found that procalcitonin is associated with insulin resistance and all components of the metabolic syndrome [3]. Our current aim is to test the prospective association of plasma procalcitonin with incident type 2 diabetes in the general population, and to compare its predictive value with that of high sensitivity C-reactive protein (hs-CRP). …
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Metadaten
Titel
Plasma procalcitonin and risk of type 2 diabetes in the general population
verfasst von
A. Abbasi
E. Corpeleijn
D. Postmus
R. T. Gansevoort
P. E. de Jong
R. O. B. Gans
J. Struck
H. L. Hillege
R. P. Stolk
G. Navis
S. J. L. Bakker
Publikationsdatum
01.09.2011
Verlag
Springer-Verlag
Erschienen in
Diabetologia / Ausgabe 9/2011
Print ISSN: 0012-186X
Elektronische ISSN: 1432-0428
DOI
https://doi.org/10.1007/s00125-011-2216-3

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