Introduction
Methods
Results
Population/calendar year | Diabetes | No diabetes | |||||||
---|---|---|---|---|---|---|---|---|---|
Number of people with amputation | Mean agea (years) | Number of total population | ARdb | Number of people with amputation | Mean agea (years) | Number of total population | ARnb | RRc | |
All major amputations | |||||||||
Total population | |||||||||
2009 | 618 | 72.4 | 678,655 | 42.3 | 554 | 69.5 | 10,198,663 | 6.1 | 6.9 |
2010 | 631 | 71.9 | 738,256 | 43.8 | 549 | 69.9 | 10,226,043 | 6.1 | 7.2 |
2011 | 590 | 71.9 | 793,883 | 37.6 | 578 | 69.9 | 10,255,320 | 6.4 | 5.9 |
2012 | 569 | 71.6 | 846,796 | 34.5 | 537 | 69.3 | 10,271,802 | 5.9 | 5.8 |
2013 | 599 | 71.9 | 896,126 | 29.9 | 542 | 69.7 | 10,269,852 | 6.0 | 5.0 |
Male population | |||||||||
2009 | 404 | 71.0 | 326,803 | 59.1 | 347 | 66.2 | 5,021,923 | 8.7 | 6.8 |
2010 | 400 | 70.5 | 354,104 | 60.8 | 336 | 66.4 | 5,038,345 | 8.5 | 7.2 |
2011 | 399 | 70.0 | 379,168 | 57.6 | 360 | 67.7 | 5,056,551 | 9.1 | 6.3 |
2012 | 385 | 69.9 | 402,725 | 52.8 | 341 | 66.9 | 5,067,837 | 8.5 | 6.2 |
2013 | 411 | 70.8 | 424,291 | 44.2 | 351 | 67.5 | 5,068,800 | 8.8 | 5.0 |
Female population | |||||||||
2009 | 214 | 75.1 | 351,852 | 28.1 | 207 | 75.1 | 5,176,740 | 4.0 | 7.1 |
2010 | 231 | 74.3 | 384,152 | 28.7 | 213 | 75.3 | 5,187,698 | 4.1 | 7.1 |
2011 | 191 | 75.7 | 414,715 | 19.3 | 218 | 73.7 | 5,198,769 | 4.2 | 4.6 |
2012 | 184 | 75.3 | 444,071 | 18 | 196 | 73.5 | 5,203,965 | 3.8 | 4.8 |
2013 | 188 | 74.3 | 471,835 | 17.7 | 191 | 73.8 | 5,201,052 | 3.7 | 4.8 |
Major amputations above the knee | |||||||||
Total population | |||||||||
2009 | 281 | 73.8 | 678,655 | 17.6 | 323 | 71.2 | 10,198,663 | 3.6 | 4.9 |
2010 | 285 | 74.4 | 738,256 | 16.6 | 300 | 72.3 | 10,226,043 | 3.4 | 4.9 |
2011 | 274 | 73.8 | 793,883 | 17.8 | 329 | 71.7 | 10,255,320 | 3.7 | 4.8 |
2012 | 259 | 74.4 | 846,796 | 12.6 | 356 | 71.0 | 10,271,802 | 4.0 | 3.2 |
2013 | 247 | 73.3 | 896,126 | 11.4 | 328 | 71.1 | 10,269,852 | 3.6 | 3.2 |
Male population | |||||||||
2009 | 173 | 72.6 | 326,803 | 22.7 | 202 | 67.8 | 5,021,923 | 5.2 | 4.4 |
2010 | 164 | 72.7 | 354,104 | 20.5 | 173 | 69.0 | 5,038,345 | 4.4 | 4.6 |
2011 | 166 | 71.9 | 379,168 | 25.7 | 202 | 69.2 | 5,056,551 | 5.2 | 5.0 |
2012 | 161 | 72.1 | 402,725 | 17.6 | 221 | 68.7 | 5,067,837 | 5.6 | 3.1 |
2013 | 159 | 71.5 | 424,291 | 16.0 | 209 | 67.8 | 5,068,800 | 5.3 | 3.1 |
Female population | |||||||||
2009 | 108 | 75.7 | 351,852 | 13.9 | 121 | 76.9 | 5,176,740 | 2.3 | 6.1 |
2010 | 121 | 76.7 | 384,152 | 13.3 | 127 | 76.6 | 5,187,698 | 2.4 | 5.5 |
2011 | 108 | 76.8 | 414,715 | 10.5 | 127 | 75.8 | 5,198,769 | 2.4 | 4.3 |
2012 | 98 | 78.2 | 444,071 | 8.4 | 135 | 74.8 | 5,203,965 | 2.6 | 3.2 |
2013 | 88 | 76.6 | 471,835 | 7.6 | 119 | 76.9 | 5,201,052 | 2.3 | 3.3 |
Major amputations below the knee | |||||||||
Total population | |||||||||
2009 | 385 | 71.3 | 678,655 | 27.6 | 271 | 67.2 | 10,198,663 | 3.0 | 9.3 |
2010 | 399 | 69.9 | 738,256 | 30.2 | 284 | 66.9 | 10,226,043 | 3.1 | 9.7 |
2011 | 360 | 70.2 | 793,883 | 22.1 | 281 | 67.9 | 10,255,320 | 3.1 | 7.2 |
2012 | 342 | 69.5 | 846,796 | 23.6 | 224 | 66.7 | 10,271,802 | 2.5 | 9.6 |
2013 | 393 | 70.6 | 896,126 | 20.5 | 256 | 68.0 | 10,269,852 | 2.8 | 7.3 |
Male population | |||||||||
2009 | 262 | 69.9 | 326,803 | 40.2 | 174 | 64.0 | 5,021,923 | 4.2 | 9.5 |
2010 | 271 | 69.3 | 354,104 | 44.4 | 185 | 63.8 | 5,038,345 | 4.6 | 9.7 |
2011 | 264 | 68.9 | 379,168 | 35.3 | 180 | 65.9 | 5,056,551 | 4.5 | 7.9 |
2012 | 251 | 68.4 | 402,725 | 38.3 | 151 | 64.9 | 5,067,837 | 3.7 | 10.2 |
2013 | 282 | 70.0 | 424,291 | 31.3 | 173 | 67.3 | 5,068,800 | 4.3 | 7.3 |
Female population | |||||||||
2009 | 123 | 74.2 | 351,852 | 16.5 | 97 | 72.9 | 5,176,740 | 1.9 | 8.9 |
2010 | 128 | 71.1 | 384,152 | 17.5 | 99 | 72.9 | 5,187,698 | 1.9 | 9.3 |
2011 | 96 | 73.8 | 414,715 | 10.4 | 101 | 71.4 | 5,198,769 | 1.9 | 5.4 |
2012 | 91 | 72.4 | 444,071 | 9.9 | 73 | 70.4 | 5,203,965 | 1.4 | 7.0 |
2013 | 111 | 72.0 | 471,835 | 11.2 | 83 | 69.4 | 5,201,052 | 1.6 | 7.1 |
Minor amputations | |||||||||
Total population | |||||||||
2009 | 1232 | 70.3 | 678,655 | 91.3 | 772 | 68.9 | 10,198,663 | 8.5 | 10.7 |
2010 | 1242 | 70.9 | 738,256 | 85.0 | 740 | 68.4 | 10,226,043 | 8.1 | 10.5 |
2011 | 1223 | 70.0 | 793,883 | 82.5 | 746 | 67.0 | 10,255,320 | 8.2 | 10.1 |
2012 | 1299 | 70.7 | 846,796 | 75.7 | 695 | 67.7 | 10,271,802 | 7.6 | 9.9 |
2013 | 1325 | 70.9 | 896,126 | 77.1 | 704 | 67.6 | 10,269,852 | 7.7 | 10.1 |
Male population | |||||||||
2009 | 860 | 68.6 | 326,803 | 139.0 | 423 | 66.5 | 5,021,923 | 10.8 | 12.9 |
2010 | 838 | 69.3 | 354,104 | 125.9 | 397 | 65.5 | 5,038,345 | 10.1 | 12.5 |
2011 | 860 | 68.7 | 379,168 | 127.2 | 407 | 65.2 | 5,056,551 | 10.3 | 12.4 |
2012 | 903 | 69.6 | 402,725 | 114.9 | 373 | 66.0 | 5,067,837 | 9.5 | 12.1 |
2013 | 935 | 69.8 | 424,291 | 119.0 | 367 | 65.4 | 5,068,800 | 9.2 | 13 |
Female population | |||||||||
2009 | 372 | 74.1 | 351,852 | 47.9 | 349 | 71.7 | 5,176,740 | 6.7 | 7.2 |
2010 | 404 | 74.3 | 384,152 | 48.5 | 343 | 71.7 | 5,187,698 | 6.6 | 7.4 |
2011 | 363 | 72.9 | 414,715 | 42.1 | 339 | 69.1 | 5,198,769 | 6.5 | 6.5 |
2012 | 396 | 73.3 | 444,071 | 41.1 | 322 | 69.8 | 5,203,965 | 6.2 | 6.6 |
2013 | 390 | 73.7 | 471,835 | 40.1 | 337 | 70.0 | 5,201,052 | 6.4 | 6.2 |
Variables | RR (95% CI) | ||
---|---|---|---|
Total population | Men | Women | |
Any major amputation | |||
Model 1a (diabetes) | |||
Calendar year | 0.920 (0.909, 0.931)* | 0.933 (0.920, 0.946)* | 0.894 (0.877, 0.911)* |
Male vs female | 2.258 (2.177, 2.342)* | – | – |
Age (years)a | |||
≥80 | 18.824 (15.162, 23.369)* | 10.618 (8.424, 13.383)* | 52.671 (33.593, 82.583)* |
70–79 | 13.688 (11.027, 16.991)* | 8.418 (6.686, 10.598)* | 34.452 (21.958, 54.056)* |
60–69 | 9.308 (7.493, 11.563)* | 6.100 (4.843, 7.682)* | 19.087 (12.132, 30.029)* |
50–59 | 6.759 (5.426, 8.419)* | 4.161 (3.293, 5.258)* | 16.967 (10.748, 26.786)* |
40–49 | 3.39 (2.673, 4.299)* | 1.857 (1.432, 2.409)* | 10.543 (6.569, 16.924)* |
Model 1b (no diabetes) | |||
Calendar year | 0.991 (0.974, 1.009) | 1.001 (0.981, 1.022) | 0.975 (0.951, 1.000) |
Male vs female | 2.242 (2.130, 2.360)* | – | – |
Age (years)a | |||
≥80 | 71.017 (63.367, 79.591)* | 59.204 (51.699, 67.799)* | 81.253 (68.314, 96.642)* |
70–79 | 38.504 (34.279, 43.249)* | 42.539 (37.225, 48.612)* | 31.441 (26.184, 37.752)* |
60–69 | 18.428 (16.345, 20.776)* | 22.005 (19.210, 25.207)* | 11.759 (9.650, 14.328)* |
50–59 | 9.538 (8.417, 10.808)* | 10.273 (8.908, 11.847)* | 8.052 (6.589, 9.840)* |
40–49 | 3.604 (3.111, 4.176)* | 4.098 (3.477, 4.830)* | 2.579 (2.002, 3.321)* |
Model 2 (both diabetes and no diabetes combined) | |||
Calendar year | 0.991 (0.974, 1.008) | 1.001 (0.980, 1.021) | 0.975 (0.950, 1.002) |
Diabetes (yes vs no) | 6.122 (5.776, 6.489)* | 6.336 (5.908, 6.796)* | 5.708 (5.211, 6.253)* |
Male vs female | 2.252 (2.174, 2.336)* | – | – |
Age (years)a | |||
≥80 | 53.132 (47.956, 59.028)* | 44.619 (39.564, 50.494)* | 65.211 (55.092, 77.842)* |
70–79 | 33.552 (30.274, 37.286)* | 33.634 (29.871, 38.007)* | 33.117 (27.880, 39.655)* |
60–69 | 19.63 (17.692, 21.839)* | 21.278 (18.890, 24.052)* | 15.080 (12.608, 18.170)* |
50–59 | 11.378 (10.218, 12.699)* | 11.572 (10.231, 13.130)* | 10.734 (8.933, 12.986)* |
40–49 | 4.192 (3.692, 4.764)* | 4.266 (3.690, 4.939)* | 4.002 (3.214, 4.995)* |
Diabetes × calendar year | 0.927 (0.905, 0.949)* | 0.932 (0.906, 0.958)* | 0.916 (0.882, 0.951)* |
Major amputation above the knee | |||
Model 1a (diabetes) | |||
Calendar year | 0.902 (0.888, 0.917)* | 0.914 (0.896, 0.933)* | 0.883 (0.863, 0.905)* |
Male vs female | 1.869 (1.783, 1.959)* | – | – |
Age (years)a | |||
≥80 | 39.803 (27.408, 57.803)* | 23.887 (15.173, 37.606)* | 74.895 (40.68, 137.884)* |
70–79 | 24.376 (16.781, 35.41)* | 15.969 (10.15, 25.125)* | 41.965 (22.769, 77.345)* |
60–69 | 14.385 (9.89, 20.922)* | 10.324 (6.557, 16.256)* | 19.257 (10.403, 35.644)* |
50–59 | 9.124 (6.247, 13.326)* | 6.197 (3.916, 9.805)* | 14.368 (7.709, 26.779)* |
40–49 | 4.681 (3.131, 6.998)* | 2.342 (1.417, 3.87)* | 11.422 (6.02, 21.671)* |
Model 1b (no diabetes) | |||
Calendar year | 1.018 (0.998, 1.039) | 1.029 (1.004, 1.054)* | 1.003 (0.974, 1.032) |
Male vs female | 2.155 (2.032, 2.285)* | – | – |
Age (years)a | |||
≥80 | 110.327 (94.446, 128.879)* | 93.062 (76.83, 112.723)* | 120.183 (95.767, 150.824)* |
70–79 | 61.266 (52.349, 71.702)* | 69.182 (57.253, 83.596)* | 48.389 (38.246, 61.223)* |
60–69 | 27.25 (23.182, 32.031)* | 33.959 (28.021, 41.155)* | 16.077 (12.499, 20.681)* |
50–59 | 12.64 (10.677, 14.965)* | 14.959 (12.246, 18.273)* | 8.535 (6.555, 11.113)* |
40–49 | 4.55 (3.741, 5.533)* | 5.241 (4.168, 6.591)* | 3.282 (2.396, 4.497)* |
Model 2 (both diabetes and no diabetes combined) | |||
Calendar year | 1.018 (1.000, 1.037) | 1.028 (1.005, 1.052)* | 1.003 (0.976, 1.031) |
Diabetes (yes vs no) | 4.747 (4.441, 5.074)* | 4.603 (4.233, 5.004)* | 4.893 (4.433, 5.400)* |
Male vs female | 2.024 (1.946, 2.105)* | – | – |
Age (years)a | |||
≥80 | 95.278 (83.499, 109.273)* | 84.078 (71.588, 99.458)* | 104.238 (85.069, 129.41)* |
70–79 | 55.2 (48.34, 63.351)* | 59.146 (50.414, 69.898)* | 49.112 (39.935, 61.166)* |
60–69 | 28.1 (24.56, 32.308)* | 33.297 (28.351, 39.388)* | 18.763 (15.119, 23.553)* |
50–59 | 14.174 (12.324, 16.373)* | 16.083 (13.617, 19.121)* | 10.681 (8.521, 13.525)* |
40–49 | 5.129 (4.36, 6.046)* | 5.321 (4.382, 6.483)* | 4.788 (3.692, 6.239)* |
Diabetes × calendar year | 0.886 (0.862, 0.910)* | 0.889 (0.86, 0.92)* | 0.881 (0.846, 0.918)* |
Major amputation below the knee | |||
Model 1a (diabetes) | |||
Calendar year | 0.926 (0.913, 0.938)* | 0.941 (0.927, 0.956)* | 0.889 (0.867, 0.911)* |
Male vs female | 2.649 (2.541, 2.762)* | – | – |
Age (years)a | |||
≥80 | 12.335 (9.902, 15.367)* | 7.638 (6.065, 9.619)* | 35.56 (21.074, 60.004)* |
70–79 | 11.139 (8.949, 13.864)* | 7.057 (5.615, 8.869)* | 31.227 (18.506, 52.692)* |
60–69 | 8.525 (6.845, 10.616)* | 5.647 (4.493, 7.097)* | 20.585 (12.17, 34.817)* |
50–59 | 6.427 (5.147, 8.026)* | 3.99 (3.164, 5.031)* | 19.349 (11.403, 32.83)* |
40–49 | 3.042 (2.388, 3.875)* | 1.795 (1.386, 2.324)* | 9.989 (5.758, 17.328)* |
Model 1b (no diabetes) | |||
Calendar year | 0.964 (0.944, 0.984)* | 0.977 (0.952, 1.002) | 0.940 (0.910, 0.971)* |
Male vs female | 2.463 (2.315, 2.621)* | – | – |
Age (years)a | |||
≥80 | 48.973 (43.346, 55.332)* | 41.896 (36.022, 48.727)* | 56.046 (46.219, 67.964)* |
70–79 | 26.496 (23.376, 30.033)* | 29.954 (25.832, 34.734)* | 19.987 (16.21, 24.644)* |
60–69 | 14.072 (12.373, 16.004)* | 16.215 (13.947, 18.852)* | 9.597 (7.682, 11.989)* |
50–59 | 8.469 (7.422, 9.664)* | 8.226 (7.025, 9.632)* | 8.97 (7.235, 11.122)* |
40–49 | 3.331 (2.851, 3.893)* | 3.805 (3.182, 4.551)* | 2.229 (1.671, 2.973)* |
Model 2 (both diabetes and no diabetes combined) | |||
Calendar year | 0.964 (0.944, 0.984)* | 0.976 (0.952, 1.001) | 0.941 (0.909, 0.973)* |
Diabetes (yes vs no) | 8.049 (7.533, 8.602)* | 8.488 (7.835, 9.198)* | 7.251 (6.491, 8.102)* |
Male vs female | 2.571 (2.469, 2.681)* | – | – |
Age (years)a | |||
≥80 | 31.797 (28.487, 35.592)* | 27.494 (24.137, 31.43)* | 39.408 (32.537, 48.219)* |
70–79 | 23.237 (20.83, 25.996)* | 22.855 (20.123, 26.057)* | 23.646 (19.455, 29.022)* |
60–69 | 15.691 (14.06, 17.561)* | 16.132 (14.207, 18.388)* | 13.513 (11.058, 16.665)* |
50–59 | 10.162 (9.078, 11.404)* | 9.556 (8.383, 10.932)* | 11.6 (9.476, 14.326)* |
40–49 | 3.826 (3.346, 4.378)* | 3.888 (3.333, 4.543)* | 3.609 (2.812, 4.642)* |
Diabetes × calendar year | 0.960 (0.934, 0.986)* | 0.963 (0.933, 0.995)* | 0.944 (0.901, 0.989)* |
Minor amputation | |||
Model 1a (diabetes) | |||
Calendar year | 0.954 (0.945, 0.962)* | 0.957 (0.948, 0.967)* | 0.946 (0.932, 0.961)* |
Male vs female | 2.528 (2.458, 2.599)* | – | – |
Age (years)a | |||
≥80 | 12.957 (11.216, 14.968)* | 9.039 (7.666, 10.658)* | 22.655 (17.640, 29.096)* |
70–79 | 10.248 (8.874, 11.835)* | 7.327 (6.221, 8.631)* | 17.735 (13.805, 22.785)* |
60–69 | 8.215 (7.112, 9.490)* | 6.204 (5.267, 7.307)* | 12.224 (9.498, 15.732)* |
50–59 | 5.897 (5.095, 6.826)* | 4.576 (3.878, 5.401)* | 7.918 (6.117, 10.250)* |
40–49 | 3.174 (2.709, 3.719)* | 2.356 (1.968, 2.821)* | 5.048 (3.829, 6.655)* |
Model 1b (no diabetes) | |||
Calendar year | 0.973 (0.959, 0.988)* | 0.963 (0.944, 0.982)* | 0.986 (0.965, 1.008) |
Male vs female | 1.541 (1.477, 1.608)* | – | – |
Age (years)a | |||
≥80 | 40.665 (37.649, 43.924)* | 42.094 (37.984, 46.65)* | 37.438 (33.474, 41.872)* |
70–79 | 19.135 (17.641, 20.756)* | 20.454 (18.394, 22.744)* | 17.29 (15.329, 19.503)* |
60–69 | 8.984 (8.243, 9.792)* | 10.976 (9.845, 12.238)* | 6.586 (5.755, 7.537)* |
50–59 | 4.66 (4.249, 5.110)* | 5.298 (4.714, 5.954)* | 3.843 (3.331, 4.434)* |
40–49 | 1.944 (1.736, 2.177)* | 2.143 (1.858, 2.471)* | 1.683 (1.410, 2.010)* |
Model 2 (both diabetes and no diabetes combined) | |||
Calendar year | 0.973 (0.954, 0.992)* | 0.962 (0.939, 0.987)* | 0.986 (0.962, 1.010) |
Diabetes (yes vs no) | 9.457 (8.906, 10.045)* | 11.955 (11.100, 12.882)* | 6.448 (5.937, 7.003)* |
Male vs female | 2.088 (2.016, 2.165)* | – | – |
Age (years)a | |||
≥80 | 25.967 (23.733, 28.462)* | 23.172 (20.694, 26.017)* | 28.283 (25.173, 31.882)* |
70–79 | 16.864 (15.410, 18.488)* | 15.823 (14.146, 17.747)* | 17.48 (15.518, 19.753)* |
60–69 | 11.615 (10.609, 12.739)* | 12.019 (10.751, 13.473)* | 9.399 (8.303, 10.669)* |
50–59 | 6.896 (6.273, 7.592)* | 7.448 (6.639, 8.376)* | 5.241 (4.585, 6.003)* |
40–49 | 2.731 (2.431, 3.068)* | 2.894 (2.516, 3.33)* | 2.392 (2.031, 2.816)* |
Diabetes × calendar year | 0.979 (0.956, 1.003)* | 0.993 (0.964, 1.023)* | 0.96 (0.928, 0.992)* |