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Erschienen in: Intensive Care Medicine 11/2003

01.11.2003 | Brief Reports

Ventilator-associated pneumonia: caveats for benchmarking

verfasst von: Philippe Eggimann, Stéphane Hugonnet, Hugo Sax, Sylvie Touveneau, Jean-Claude Chevrolet, Didier Pittet

Erschienen in: Intensive Care Medicine | Ausgabe 11/2003

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Abstract

Objective

To determine the influence of using different denominators on risk estimates of ventilator-associated pneumonia (VAP).

Design and setting

Prospective cohort study in the medical ICU of a large teaching hospital.

Patients

All consecutive patients admitted for more than 48 h between October 1995 and November 1997.

Measurements and results

We recorded all ICU-acquired infections using modified CDC criteria. VAP rates were reported per 1,000 patient-days, patient-days at risk, ventilator-days, and ventilator-days at risk. Of the 1,068 patients admitted, VAP developed in 106 (23.5%) of those mechanically ventilated. The incidence of the first episode of VAP was 22.8 per 1,000 patient-days (95% CI 18.7–27.6), 29.6 per 1,000 patient-days at risk (24.2–35.8), 35.7 per 1,000 ventilator-days (29.2–43.2), and 44.0 per 1,000 ventilator-days at risk (36.0–53.2). When considering all episodes of VAP (n=127), infection rates were 27.3 episodes per 1,000 ICU patient-days (95% CI 22.6–32.1) and 42.8 episodes per 1,000 ventilator-days (35.3–50.2).

Conclusions

The method of reporting VAP rates has a significant impact on risk estimates. Accordingly, clinicians and hospital management in charge of patient-care policies should be aware of how to read and compare nosocomial infection rates.
Literatur
1.
Zurück zum Zitat Fagon JY, Chastre J, Vuagnat A, Trouillet JL, Novara A, Gibert C (1996) Nosocomial pneumonia and mortality among patients in intensive care units. JAMA 275:866–869PubMed Fagon JY, Chastre J, Vuagnat A, Trouillet JL, Novara A, Gibert C (1996) Nosocomial pneumonia and mortality among patients in intensive care units. JAMA 275:866–869PubMed
2.
Zurück zum Zitat Heyland DK, Cook DJ, Griffith L, Keenan, SP, Brun-Buisson C (1999) The attributable morbidity and mortality of ventilator-associated pneumonia in the critically ill patient. The Canadian Critical Trials Group. Am J Respir Crit Care Med 159:1249–1256PubMed Heyland DK, Cook DJ, Griffith L, Keenan, SP, Brun-Buisson C (1999) The attributable morbidity and mortality of ventilator-associated pneumonia in the critically ill patient. The Canadian Critical Trials Group. Am J Respir Crit Care Med 159:1249–1256PubMed
3.
Zurück zum Zitat Vincent JL, Bihari DJ, Suter PM, Bruining, HA, White J, Nicolas-Chanoin MH, Wolff M, Spencer RC, Hemmer M (1995) The prevalence of nosocomial infection in intensive care units in Europe. Results of the European Prevalence of Infection in Intensive Care (EPIC) study. JAMA 274:639–644PubMed Vincent JL, Bihari DJ, Suter PM, Bruining, HA, White J, Nicolas-Chanoin MH, Wolff M, Spencer RC, Hemmer M (1995) The prevalence of nosocomial infection in intensive care units in Europe. Results of the European Prevalence of Infection in Intensive Care (EPIC) study. JAMA 274:639–644PubMed
4.
Zurück zum Zitat Cook DJ, Walter SD, Cook RJ, Griffith LE, Guyatt GH, Leasa D, Jaeschke RZ, Brun-Buisson C (1998) Incidence of and risk factors for ventilator-associated pneumonia in critically ill patients. Ann Intern Med 129:433–440PubMed Cook DJ, Walter SD, Cook RJ, Griffith LE, Guyatt GH, Leasa D, Jaeschke RZ, Brun-Buisson C (1998) Incidence of and risk factors for ventilator-associated pneumonia in critically ill patients. Ann Intern Med 129:433–440PubMed
5.
Zurück zum Zitat Kollef MH (1999) Epidemiology and risk factors for nosocomial pneumonia. Emphasis on prevention. Clin Chest Med 20:653–670PubMed Kollef MH (1999) Epidemiology and risk factors for nosocomial pneumonia. Emphasis on prevention. Clin Chest Med 20:653–670PubMed
6.
Zurück zum Zitat Chastre J, Fagon JY (2002) Ventilator-associated pneumonia. Am J Respir Crit Care Med 165:867–903PubMed Chastre J, Fagon JY (2002) Ventilator-associated pneumonia. Am J Respir Crit Care Med 165:867–903PubMed
7.
Zurück zum Zitat Eggimann P, Pittet D (2001) Infection control in the ICU. Chest 120:2059–2093PubMed Eggimann P, Pittet D (2001) Infection control in the ICU. Chest 120:2059–2093PubMed
8.
Zurück zum Zitat National Nosocomial Infections Surveillance (NNIS) system report. Data summary from January 1992-June 2001 (2002) Am J Infect Control 29:404–421 National Nosocomial Infections Surveillance (NNIS) system report. Data summary from January 1992-June 2001 (2002) Am J Infect Control 29:404–421
10.
Zurück zum Zitat Eggimann P, Harbarth S, Constantin MN, Touveneau S, Chevrolet JC, Pittet D (2000) Impact of a prevention strategy targeted at vascular-access care on incidence of infections acquired in intensive care. Lancet 355:1864–1868PubMed Eggimann P, Harbarth S, Constantin MN, Touveneau S, Chevrolet JC, Pittet D (2000) Impact of a prevention strategy targeted at vascular-access care on incidence of infections acquired in intensive care. Lancet 355:1864–1868PubMed
11.
Zurück zum Zitat Garner JS, Jarvis WR, Emori TG, Toran TC, Hughes JM (1988) CDC definitions for nosocomial infections. Am J Infect Control 16:128–140PubMed Garner JS, Jarvis WR, Emori TG, Toran TC, Hughes JM (1988) CDC definitions for nosocomial infections. Am J Infect Control 16:128–140PubMed
12.
Zurück zum Zitat American Thoracic Society (1995) Hospital acquired pneumonia in adults: diagnosis, assessment of severity, initial antimicrobial therapy and preventive strategies. A consensus statement. Am J Respir Crit Care Med 153:1711–1725 American Thoracic Society (1995) Hospital acquired pneumonia in adults: diagnosis, assessment of severity, initial antimicrobial therapy and preventive strategies. A consensus statement. Am J Respir Crit Care Med 153:1711–1725
13.
Zurück zum Zitat Haley RW, Culver DH, White JW, Morgan WM, Emori TG, Munn VP, Hooton TM (1985) The efficacy of infection surveillance and control programs in preventing nosocomial infections in US hospitals. Am J Epidemiol 121:182–205PubMed Haley RW, Culver DH, White JW, Morgan WM, Emori TG, Munn VP, Hooton TM (1985) The efficacy of infection surveillance and control programs in preventing nosocomial infections in US hospitals. Am J Epidemiol 121:182–205PubMed
14.
Zurück zum Zitat Pittet D, Hugonnet S, Harbarth S, Mourouga P, Sauvan V, Touveneau S, Perneger TV, and the members of the Infection Control Programme (2000) Effectiveness of a hospital-wide programme to improve compliance with hand hygiene. Lancet 356:1307–1312CrossRefPubMed Pittet D, Hugonnet S, Harbarth S, Mourouga P, Sauvan V, Touveneau S, Perneger TV, and the members of the Infection Control Programme (2000) Effectiveness of a hospital-wide programme to improve compliance with hand hygiene. Lancet 356:1307–1312CrossRefPubMed
16.
Zurück zum Zitat Richards C, Emori TG. Edwards J, Fridkin S, Tolson J, Gaynes R (2002) Characteristics of hospitals and infection control professionals participating in the National Nosocomial Infections Surveillance System 1999. Am J Infect Control 29:400–403CrossRef Richards C, Emori TG. Edwards J, Fridkin S, Tolson J, Gaynes R (2002) Characteristics of hospitals and infection control professionals participating in the National Nosocomial Infections Surveillance System 1999. Am J Infect Control 29:400–403CrossRef
17.
Zurück zum Zitat Pittet D, Harbarth S (1998) What techniques for diagnosis of ventilator-associated pneumonia? Lancet 352:83–84CrossRef Pittet D, Harbarth S (1998) What techniques for diagnosis of ventilator-associated pneumonia? Lancet 352:83–84CrossRef
18.
Zurück zum Zitat Grossman RF, Fein A (2000) Evidence-based assessment of diagnostic tests for ventilator-associated pneumonia: executive summary. Chest 117 [Suppl 2]:177S–181S Grossman RF, Fein A (2000) Evidence-based assessment of diagnostic tests for ventilator-associated pneumonia: executive summary. Chest 117 [Suppl 2]:177S–181S
19.
Zurück zum Zitat Fagon JY, Chastre J, Wolff M, Gervais C, Parer-Aubas S, Stephan F, Similowski T, Mercat A, Diehl JL, Sollet JP, Tenaillon A (2000) Invasive and noninvasive strategies for management of suspected ventilator-associated pneumonia. A randomized trial. Ann Intern Med 132:621–630PubMed Fagon JY, Chastre J, Wolff M, Gervais C, Parer-Aubas S, Stephan F, Similowski T, Mercat A, Diehl JL, Sollet JP, Tenaillon A (2000) Invasive and noninvasive strategies for management of suspected ventilator-associated pneumonia. A randomized trial. Ann Intern Med 132:621–630PubMed
20.
Zurück zum Zitat Sax H, Pittet D, and the Swiss-NOSO Network (2002) Interhospital differences in nosocomial infection rates–importance of case-mix adjustment. Arch Intern Med 162:2437–2442CrossRefPubMed Sax H, Pittet D, and the Swiss-NOSO Network (2002) Interhospital differences in nosocomial infection rates–importance of case-mix adjustment. Arch Intern Med 162:2437–2442CrossRefPubMed
21.
Zurück zum Zitat Cook D (2000) Ventilator associated pneumonia: perspectives on the burden of illness. Intensive Care Med 26 [Suppl 1]:S31–S37 Cook D (2000) Ventilator associated pneumonia: perspectives on the burden of illness. Intensive Care Med 26 [Suppl 1]:S31–S37
Metadaten
Titel
Ventilator-associated pneumonia: caveats for benchmarking
verfasst von
Philippe Eggimann
Stéphane Hugonnet
Hugo Sax
Sylvie Touveneau
Jean-Claude Chevrolet
Didier Pittet
Publikationsdatum
01.11.2003
Verlag
Springer-Verlag
Erschienen in
Intensive Care Medicine / Ausgabe 11/2003
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-003-1991-9

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