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01.02.2005 | Erratum
Post-ICU mortality in critically ill infected patients: an international study
Erschienen in: Intensive Care Medicine | Ausgabe 2/2005
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Table 1 was published with a column missing, and the legend of Table 3 was incorrect. The correct versions of these tables are reproduced here.
Table 1
Patient characteristics, associated Post-ICU in-hospital mortality frequencies and risk factors of PIIHM (bivariate logistic regression): qualitative variables. Odds ratio computed by bivariate logistic regression; 95% confidence interval calculated by bivariate logistic regression
|
Variable
|
All patients
(n=1,872)
|
Survivors on the ward
(n=1,677, 89.6%)
|
Dead in ward
(n=195, 10.4)
|
Odds ratio
95% confidence interval
|
p
|
||||
|---|---|---|---|---|---|---|---|---|---|
|
n
|
%
|
n
|
%
|
n
|
%
|
n
|
%
|
||
|
Sex
|
|
|
|
|
|||||
|
Male
|
1,171
|
62.6
|
1,047
|
89.4
|
124
|
10.6
|
1
|
|
|
|
Female
|
701
|
37.4
|
630
|
89.9
|
71
|
10.1
|
0.95
|
0.70–1.30
|
0.75
|
|
Admission categories
|
|
|
|
|
|
|
|
||
|
Scheduled surgery
|
219
|
11.7
|
201
|
91.8
|
18
|
8.2
|
1
|
||
|
Medical
|
1,180
|
63.0
|
1,047
|
88.7
|
133
|
11.3
|
1.42
|
0.85–2.37
|
0.18
|
|
Emergent surgery
|
333
|
17.8
|
294
|
88.3
|
39
|
11.7
|
1.48
|
0.82–2.66
|
0.19
|
|
Trauma
|
140
|
7.5
|
135
|
96.4
|
5
|
3.6
|
0.41
|
0.15–1.14
|
0.09
|
|
Comorbidities
|
|
|
|
|
|
|
|
||
|
Chronic respiratory failure
|
98
|
5.2
|
81
|
82.7
|
17
|
17.4
|
1.88
|
1.09–3.25
|
0.02
|
|
Chronic heart failure
|
168
|
9.0
|
137
|
81.5
|
31
|
18.5
|
2.12
|
1.39–3.24
|
0.0005
|
|
Chronic renal failure
|
167
|
8.9
|
130
|
77.8
|
37
|
22.2
|
2.79
|
1.87–4.16
|
<0.0001
|
|
Cirrhosis
|
96
|
5.1
|
77
|
80.2
|
19
|
19.8
|
2.24
|
1.33–3.80
|
0.003
|
|
Immunosuppression
|
471
|
25.2
|
396
|
84.1
|
75
|
15.9
|
2.02
|
1.48–2.76
|
<0.0001
|
|
Chronic obstructive pulmonary disease
|
334
|
17.8
|
291
|
87.1
|
43
|
12.9
|
1.35
|
0.94–1.93
|
0.11
|
|
McCabe score
|
|
|
|
|
|
|
|
||
|
1
|
1,267
|
67.7
|
1,165
|
91.9
|
102
|
8.1
|
1
|
||
|
2
|
496
|
26.5
|
427
|
86.1
|
69
|
13.9
|
1.85
|
1.33–2.55
|
0.0002
|
|
3
|
109
|
5.8
|
85
|
78.0
|
24
|
22.0
|
3.23
|
1.96–5.30
|
<0.0001
|
|
Reason for ICU admission
|
|
|
|
|
|
|
|
||
|
Coma
|
184
|
9.8
|
166
|
90.2
|
18
|
9.7
|
0.93
|
0.56–1.54
|
0.77
|
|
Respiratory failure
|
804
|
42.9
|
720
|
89.6
|
84
|
10.5
|
1.01
|
0.75–1.36
|
0.97
|
|
Renal failure
|
133
|
7.1
|
109
|
82.0
|
24
|
18.0
|
2.02
|
1.26–3.23
|
0.003
|
|
Shock
|
378
|
20.2
|
327
|
86.5
|
51
|
13.5
|
1.46
|
1.04–2.06
|
0.03
|
|
Transfer from another hospital
|
329
|
17.6
|
302
|
91.8
|
27
|
8.2
|
0.73
|
0.48–1.12
|
0.15
|
|
ICU discharge on the weekend
|
471
|
25.2
|
430
|
91.3
|
41
|
8.7
|
0.77
|
0.54–1.11
|
0.16
|
|
Inotropic or vasopressor treatment
|
710
|
37.9
|
610
|
85.9
|
100
|
14.1
|
1.84
|
1.37–2.48
|
<0.0001
|
|
Ventilatory assistance (invasive or noninvasive)
|
1,366
|
73.0
|
1,213
|
88.8
|
153
|
11.2
|
1.39
|
0.97–1.99
|
0.07
|
|
Renal replacement therapy
|
206
|
11.0
|
177
|
85.9
|
29
|
14.1
|
1.48
|
0.97–2.26
|
0.07
|
Table 3
Characteristics of infections, associated post-ICU in-hospital mortality (PIIHM) frequencies and risk factors of PIIHM (bivariate logistic regression). Primary bacteremia include catheter-related infections and endocarditis; other sites include neurological, ears, nose, and throat (sinusitis, epiglottitis, otitis, tracheitis), thoracic, genital tract, skin and soft tissue, and bone and joint. Odds ratio computed by bivariate logistic regression; 95% confidence interval calculated by bivariate logistic regression. Some patients had infection at more than one site, and at more than one organism
|
|
All patients (n=1,872)
|
Survivors on the ward (n=1,677)
|
Dead on the ward (n=195)
|
Odds ratio
|
95% confidence interval
|
P
|
|||
|---|---|---|---|---|---|---|---|---|---|
|
n
|
%
|
n
|
%
|
n
|
%
|
||||
|
Origin of infection
|
|
|
|
|
|
|
|
|
|
|
Community-acquired
|
946
|
50.5
|
875
|
92.5
|
71
|
7.5
|
1
|
–
|
–
|
|
Hospital-acquired
|
593
|
31.7
|
502
|
84.7
|
91
|
15.3
|
2.23
|
1.61–3.11
|
<0.0001
|
|
ICU-acquired
|
333
|
17.8
|
298
|
89.5
|
35
|
10.5
|
1.36
|
0.88–2.09
|
0.17
|
|
Documentation of infection
|
|
|
|
|
|
|
|
|
|
|
Microbiologically documented
|
1,184
|
63.3
|
1,038
|
87.7
|
146
|
12.3
|
1.83
|
1.31–2.57
|
0.0004
|
|
Clinical
|
688
|
36.8
|
639
|
92.9
|
49
|
7.1
|
1
|
–
|
–
|
|
Site of infection
|
|
|
|
|
|
|
|
|
|
|
Pulmonary
|
1,133
|
60.5
|
1,031
|
91.0
|
102
|
9.0
|
0.69
|
0.51–0.93
|
0.01
|
|
Gastrointestinal
|
236
|
12.6
|
206
|
87.3
|
30
|
12.7
|
1.30
|
0.86–1.97
|
0.22
|
|
Urinary tract
|
196
|
10.5
|
172
|
87.8
|
24
|
12.2
|
1.23
|
0.77–1.94
|
0.38
|
|
Primary bacteremia
|
198
|
10.6
|
167
|
84.3
|
31
|
15.7
|
1.71
|
1.13–2.59
|
0.01
|
|
Unknown
|
40
|
2.1
|
37
|
92.5
|
3
|
7.5
|
0.69
|
0.21–2.27
|
0.54
|
|
Other
|
306
|
16.4
|
275
|
89.9
|
31
|
10.1
|
0.96
|
0.64–1.44
|
0.86
|
|
Micro-organisms
|
|
|
|
|
|
|
|
|
|
|
Staphylococcus aureus
|
229
|
12.2
|
198
|
86.5
|
31
|
13.5
|
1.41
|
0.94–2.13
|
0.10
|
|
Gram-positive cocci other
|
392
|
20.9
|
347
|
88.5
|
45
|
11.5
|
1.15
|
0.81–1.64
|
0.44
|
|
Aerobic Gram-negative bacilli
|
208
|
11.1
|
180
|
86.5
|
28
|
13.5
|
1.39
|
0.91–2.14
|
0.12
|
|
Candida and fungi
|
108
|
5.7
|
91
|
84.3
|
17
|
15.7
|
1.66
|
0.97–2.86
|
0.06
|
|
Enterobacteriaceae
|
515
|
27.5
|
456
|
88.5
|
59
|
11.5
|
1.16
|
0.84–1.61
|
0.36
|