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Erschienen in: Intensive Care Medicine 7/2006

01.07.2006 | Original

Under-humidification and over-humidification during moderate induced hypothermia with usual devices

verfasst von: François Lellouche, Siham Qader, Solenne Taille, Aissam Lyazidi, Laurent Brochard

Erschienen in: Intensive Care Medicine | Ausgabe 7/2006

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Abstract

Objective

In mechanically ventilated patients with induced hypothermia, the efficacy of heat and moisture exchangers and heated humidifiers to adequately humidify the airway is poorly known. The aim of the study was to assess the efficacy of different humidification devices during moderate hypothermia.

Design

Prospective, cross-over randomized study.

Settings

Medical Intensive Care Unit in a University Hospital.

Patients and participants

Nine adult patients hospitalized after cardiac arrest in whom moderate hypothermia was induced (33°C for 24 h).

Interventions

Patients were ventilated at admission (period designated “normothermia”) with a heat and moisture exchanger, and were randomly ventilated during hypothermia with a heat and moisture exchanger, a heated humidifier, and an active heat and moisture exchanger.

Measurements and results

Core temperature, inspired and expired gas absolute and relative humidity were measured. Each system demonstrated limitations in its ability to humidify gases in the specific situation of hypothermia. Performances of heat and moisture exchangers were closely correlated to core temperature (r 2 = 0.84). During hypothermia, heat and moisture exchangers led to major under-humidification, with absolute humidity below 25 mgH2O/l. The active heat and moisture exchanger slightly improved humidification. Heated humidifiers were mostly adequate but led to over-humidification in some patients, with inspiratory absolute humidity higher than maximal water content at 33°C with a positive balance between inspiratory and expiratory water content.

Conclusions

These results suggest that in the case of moderate hypothermia, heat and moisture exchangers should be used cautiously and that heated humidifiers may lead to over-humidification with the currently recommended settings.
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Metadaten
Titel
Under-humidification and over-humidification during moderate induced hypothermia with usual devices
verfasst von
François Lellouche
Siham Qader
Solenne Taille
Aissam Lyazidi
Laurent Brochard
Publikationsdatum
01.07.2006
Verlag
Springer-Verlag
Erschienen in
Intensive Care Medicine / Ausgabe 7/2006
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-006-0192-8

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