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Erschienen in: Intensive Care Medicine 12/2006

01.12.2006 | Pediatric Original

Retrospective evaluation of a paediatric intensivist-led flexible bronchoscopy service

verfasst von: Soumendu S. Manna, Andrew Durward, Shyamala Moganasundram, Shane M. Tibby, Ian A. Murdoch

Erschienen in: Intensive Care Medicine | Ausgabe 12/2006

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Abstract

Objective

To demonstrate the diagnostic yield, therapeutic role and safety of flexible bronchoscopy via an intensivist-led service in critically ill children.

Design

Retrospective chart review.

Setting

Regional paediatric intensive care unit.

Measurements and results

One hundred forty-eight flexible bronchoscopies were performed by two intensivists on 134 patients (median age 16.5 months) over a 2.5-year period. Eighty-eight percent of patients required mechanical ventilation, and 22% were receiving inotropes. Case mix included general (n = 77), cardiac surgery (n = 18), cardiology (n = 13), ear-nose-and-throat surgery (n = 17), oncology (n = 8) and renal (n = 1). The indication for bronchoscopy was defined a priori according to one of four categories: suspected upper airway disease (n = 32); lower airway disease (n = 70); investigation of pulmonary disease (n = 25); and extubation failure (n = 21). Bronchoscopy was generally performed soon after PICU admission, at a median time of 1.5 days for the former three categories, and 4 days for extubation failure group. A positive yield from bronchoscopy (diagnosis that explained the clinical condition or influenced patient management) was present in 113 of 148 (76%) procedures, varying within groups from 44% (pulmonary disease) to 90% (extubation failure).Ten percent of patients developed a fall in oxygen saturations > 20% during the procedure and 17% required a bolus of at least 10 ml/kg of 0.9% saline for hypotension.

Conclusions

Critically ill patients with respiratory problems may benefit from a PICU-led bronchoscopy service as the yield for positive bronchoscopic finding is high, particularly for upper airway problems or extubation failure.
Literatur
1.
Zurück zum Zitat Wood RE (2001) The emerging role of flexible bronchoscopy in pediatrics. Clin Chest Med 22:311–317PubMedCrossRef Wood RE (2001) The emerging role of flexible bronchoscopy in pediatrics. Clin Chest Med 22:311–317PubMedCrossRef
2.
Zurück zum Zitat Nussbaum E (2002) Pediatric fiberoptic bronchoscopy: clinical experience with 2,836 bronchoscopies. Pediatr Crit Care Med 3:171–176PubMedCrossRef Nussbaum E (2002) Pediatric fiberoptic bronchoscopy: clinical experience with 2,836 bronchoscopies. Pediatr Crit Care Med 3:171–176PubMedCrossRef
3.
Zurück zum Zitat Wood RE, Sherman JM (1980) Pediatric flexible bronchoscopy. Ann Otol Rhinol Laryngol 89:414–416PubMed Wood RE, Sherman JM (1980) Pediatric flexible bronchoscopy. Ann Otol Rhinol Laryngol 89:414–416PubMed
4.
Zurück zum Zitat Perez-Ruiz E, Perez-Frias J, Martinez-Gonzalez B, Martinez-Aran T, Milano-Manso G, Martinez-Valverde A (2001) Pediatric fiberoptic bronchoscopy. Analysis of a decade. An Esp Pediatr 55:421–428PubMed Perez-Ruiz E, Perez-Frias J, Martinez-Gonzalez B, Martinez-Aran T, Milano-Manso G, Martinez-Valverde A (2001) Pediatric fiberoptic bronchoscopy. Analysis of a decade. An Esp Pediatr 55:421–428PubMed
5.
Zurück zum Zitat Naguib ML, Streetman DS, Clifton S, Nasr SZ (2005) Use of laryngeal mask airway in flexible bronchoscopy in infants and children. Pediatr Pulmonol 39:56–63PubMedCrossRef Naguib ML, Streetman DS, Clifton S, Nasr SZ (2005) Use of laryngeal mask airway in flexible bronchoscopy in infants and children. Pediatr Pulmonol 39:56–63PubMedCrossRef
6.
Zurück zum Zitat Godfrey S, Avital A, Maayan C, Rotschild M, Springer C (1997) Yield from flexible bronchoscopy in children. Pediatr Pulmonol 23:261–269PubMedCrossRef Godfrey S, Avital A, Maayan C, Rotschild M, Springer C (1997) Yield from flexible bronchoscopy in children. Pediatr Pulmonol 23:261–269PubMedCrossRef
7.
Zurück zum Zitat de Blic J, Marchac V, Scheinmann P (2002) Complications of flexible bronchoscopy in children: prospective study of 1,328 procedures. Eur Respir J 20:1271–1276PubMedCrossRef de Blic J, Marchac V, Scheinmann P (2002) Complications of flexible bronchoscopy in children: prospective study of 1,328 procedures. Eur Respir J 20:1271–1276PubMedCrossRef
8.
Zurück zum Zitat Nussbaum E (1982) Flexible fiberoptic bronchoscopy and laryngoscopy in children under 2 years of age: diagnostic and therapeutic applications of a new pediatric flexible fiberoptic bronchoscope. Crit Care Med 10:770–772PubMedCrossRef Nussbaum E (1982) Flexible fiberoptic bronchoscopy and laryngoscopy in children under 2 years of age: diagnostic and therapeutic applications of a new pediatric flexible fiberoptic bronchoscope. Crit Care Med 10:770–772PubMedCrossRef
9.
10.
Zurück zum Zitat Fan LL, Sparks LM, Fix FJ (1988) Flexible fiberoptic endoscopy for airway problems in a pediatric intensive care unit. Chest 93:556–560PubMed Fan LL, Sparks LM, Fix FJ (1988) Flexible fiberoptic endoscopy for airway problems in a pediatric intensive care unit. Chest 93:556–560PubMed
11.
Zurück zum Zitat Bar-Zohar D, Sivan Y (2004) The yield of flexible fiberoptic bronchoscopy in pediatric intensive care patients. Chest 126:1353–1359PubMedCrossRef Bar-Zohar D, Sivan Y (2004) The yield of flexible fiberoptic bronchoscopy in pediatric intensive care patients. Chest 126:1353–1359PubMedCrossRef
12.
Zurück zum Zitat Garcia Garcia E, Perez Ruiz E, Quesada Rodriguez L, Milano Manso G, Perez Frias J, Calvo Macias C, Martinez Valverde A (1999) Usefulness of fiberoptic bronchoscopy in critical paediatric care. Arch Bronconeumol 35:525–528 Garcia Garcia E, Perez Ruiz E, Quesada Rodriguez L, Milano Manso G, Perez Frias J, Calvo Macias C, Martinez Valverde A (1999) Usefulness of fiberoptic bronchoscopy in critical paediatric care. Arch Bronconeumol 35:525–528
13.
Zurück zum Zitat Slater A, Shann F, Pearson G (2003) PIM2: a revised version of the Paediatric Index of Mortality. Intensive Care Med 29:278–285PubMed Slater A, Shann F, Pearson G (2003) PIM2: a revised version of the Paediatric Index of Mortality. Intensive Care Med 29:278–285PubMed
14.
Zurück zum Zitat Nielson DW, Ku PL, Egger M (2000) Topical lidocaine exaggerates laryngomalacia during flexible bronchoscopy. Am J Respir Crit Care Med 161:147–151PubMed Nielson DW, Ku PL, Egger M (2000) Topical lidocaine exaggerates laryngomalacia during flexible bronchoscopy. Am J Respir Crit Care Med 161:147–151PubMed
15.
Zurück zum Zitat Gibson NA, Coutts JA, Paton JY (1994) Flexible bronchoscopy under 10 kg. Respir Med 88:131–134PubMedCrossRef Gibson NA, Coutts JA, Paton JY (1994) Flexible bronchoscopy under 10 kg. Respir Med 88:131–134PubMedCrossRef
16.
Zurück zum Zitat Corno A, Giamberti A, Giannico S, Marino B, Rossi E, Marcelletti C, Kirklin JK (1990) Airway obstructions associated with congenital heart disease in infancy. J Thorac Cardiovasc Surg 99:1091–1098PubMed Corno A, Giamberti A, Giannico S, Marino B, Rossi E, Marcelletti C, Kirklin JK (1990) Airway obstructions associated with congenital heart disease in infancy. J Thorac Cardiovasc Surg 99:1091–1098PubMed
17.
Zurück zum Zitat Davis DA, Tucker JA, Russo P (1993) Management of airway obstruction in patients with congenital heart defects. Ann Otol Rhinol Laryngol 102:163–166PubMed Davis DA, Tucker JA, Russo P (1993) Management of airway obstruction in patients with congenital heart defects. Ann Otol Rhinol Laryngol 102:163–166PubMed
18.
Zurück zum Zitat Lee SL, Cheung YF, Leung MP, Ng YK, Tsoi NS (2002) Airway obstruction in children with congenital heart disease: assessment by flexible bronchoscopy. Pediatr Pulmonol 34:304–311PubMedCrossRef Lee SL, Cheung YF, Leung MP, Ng YK, Tsoi NS (2002) Airway obstruction in children with congenital heart disease: assessment by flexible bronchoscopy. Pediatr Pulmonol 34:304–311PubMedCrossRef
19.
Zurück zum Zitat Manna SS, Shaw J, Tibby SM, Durward A (2003) Treatment of plastic bronchitis in acute chest syndrome of sickle cell disease with intratracheal rhDNase. Arch Dis Child 88:626–627PubMedCrossRef Manna SS, Shaw J, Tibby SM, Durward A (2003) Treatment of plastic bronchitis in acute chest syndrome of sickle cell disease with intratracheal rhDNase. Arch Dis Child 88:626–627PubMedCrossRef
20.
Zurück zum Zitat Durward A, Forte V, Shemie SD (2000) Resolution of mucus plugging and atelectasis after intratracheal rhDNase therapy in a mechanically ventilated child with refractory status asthmaticus. Crit Care Med 28:560–562PubMedCrossRef Durward A, Forte V, Shemie SD (2000) Resolution of mucus plugging and atelectasis after intratracheal rhDNase therapy in a mechanically ventilated child with refractory status asthmaticus. Crit Care Med 28:560–562PubMedCrossRef
21.
Zurück zum Zitat Patel A, Harrison E, Durward A, Murdoch IA (2000) Intratracheal recombinant human deoxyribonuclease in acute life-threatening asthma refractory to conventional treatment. Br J Anaesth 84:505–750PubMed Patel A, Harrison E, Durward A, Murdoch IA (2000) Intratracheal recombinant human deoxyribonuclease in acute life-threatening asthma refractory to conventional treatment. Br J Anaesth 84:505–750PubMed
22.
Zurück zum Zitat Holmgren NL, Cordova M, Ortuzar P, Sanchez I (2002) Role of flexible bronchoscopy in the re-expansion of persistent atelectasis in children. Arch Bronconeumol 38:367–371PubMed Holmgren NL, Cordova M, Ortuzar P, Sanchez I (2002) Role of flexible bronchoscopy in the re-expansion of persistent atelectasis in children. Arch Bronconeumol 38:367–371PubMed
23.
Zurück zum Zitat Moser C, Nussbaum E, Cooper DM (2001) Plastic bronchitis and the role of bronchoscopy in the acute chest syndrome of sickle cell disease. Chest 120:608–613PubMedCrossRef Moser C, Nussbaum E, Cooper DM (2001) Plastic bronchitis and the role of bronchoscopy in the acute chest syndrome of sickle cell disease. Chest 120:608–613PubMedCrossRef
24.
Zurück zum Zitat Stokes DC, Shenep JL, Parham D, Bozeman PM, Marienche KW, Mackert PW (1989) Role of flexible bronchoscopy in the diagnosis of pulmonary infiltrates in pediatric patients with cancer. J Pediatr 115:561–567PubMedCrossRef Stokes DC, Shenep JL, Parham D, Bozeman PM, Marienche KW, Mackert PW (1989) Role of flexible bronchoscopy in the diagnosis of pulmonary infiltrates in pediatric patients with cancer. J Pediatr 115:561–567PubMedCrossRef
25.
Zurück zum Zitat McCubbin MM, Trigg ME, Hendricker CM, Wagener JS (1992) Bronchoscopy with bronchoalveolar lavage in the evaluation of pulmonary complications of bone marrow transplantation in children. Pediatr Pulmonol 12:43–47PubMed McCubbin MM, Trigg ME, Hendricker CM, Wagener JS (1992) Bronchoscopy with bronchoalveolar lavage in the evaluation of pulmonary complications of bone marrow transplantation in children. Pediatr Pulmonol 12:43–47PubMed
26.
Zurück zum Zitat Lanino E, Sacco O, Kotitsa Z, Rabagliati A, Castagnola E, Garaventa A, Dallorso S, Gandolfo A, Manfredini L, Venzano P, Savioli C, Maccio L, Dini G, Rossi GA (1996) Fiberoptic bronchoscopy and bronchoalveolar lavage for the evaluation of pulmonary infiltrates after BMT in children. Bone Marrow Transplant;18:117–120PubMed Lanino E, Sacco O, Kotitsa Z, Rabagliati A, Castagnola E, Garaventa A, Dallorso S, Gandolfo A, Manfredini L, Venzano P, Savioli C, Maccio L, Dini G, Rossi GA (1996) Fiberoptic bronchoscopy and bronchoalveolar lavage for the evaluation of pulmonary infiltrates after BMT in children. Bone Marrow Transplant;18:117–120PubMed
27.
Zurück zum Zitat Schellhase DE, Graham LM, Fix EJ, Sparks LM, Fan LL (1990) Diagnosis of tracheal injury in mechanically ventilated premature infants by flexible bronchoscopy. A pilot study. Chest 98:1219–1225PubMed Schellhase DE, Graham LM, Fix EJ, Sparks LM, Fan LL (1990) Diagnosis of tracheal injury in mechanically ventilated premature infants by flexible bronchoscopy. A pilot study. Chest 98:1219–1225PubMed
Metadaten
Titel
Retrospective evaluation of a paediatric intensivist-led flexible bronchoscopy service
verfasst von
Soumendu S. Manna
Andrew Durward
Shyamala Moganasundram
Shane M. Tibby
Ian A. Murdoch
Publikationsdatum
01.12.2006
Verlag
Springer-Verlag
Erschienen in
Intensive Care Medicine / Ausgabe 12/2006
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-006-0351-y

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