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01.07.2009 | Review

The impact of obesity on outcomes after critical illness: a meta-analysis

verfasst von: Charles W. Hogue Jr, Joshua D. Stearns, Elizabeth Colantuoni, Karen A. Robinson, Tracey Stierer, Nanhi Mitter, Peter J. Pronovost, Dale M. Needham

Erschienen in: Intensive Care Medicine | Ausgabe 7/2009

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Abstract

Purpose

To assess whether obesity is associated with mortality or other adverse intensive care unit (ICU) and post-ICU outcomes.

Methods

A meta-analysis of studies from PubMed and EMBASE databases.

Results

Twenty-two studies (n = 88,051 patients) were included. Pooled analysis demonstrated no difference in ICU mortality, but lower hospital mortality for obese and morbidly obese subjects (RR 0.76; 95% CI 0.59, 0.92; RR 0.83; 95% CI 0.66, 1.04, respectively) versus normal weight subjects. There was no association between obesity and duration of mechanical ventilation or ICU stay. Morbidly obese versus normal weight patients had longer hospitalizations. No study reported physical function, mental health, or quality of life outcomes after discharge.

Conclusions

Obesity is not associated with increased risk for ICU mortality, but may be associated with lower hospital mortality. There is a critical lack of research on how obesity may affect complications of critical illness and patient long-term outcomes.

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Titel: The impact of obesity on outcomes after critical illness: a meta-analysis
verfasst von: Charles W. Hogue Jr
Joshua D. Stearns
Elizabeth Colantuoni
Karen A. Robinson
Tracey Stierer
Nanhi Mitter
Peter J. Pronovost
Dale M. Needham
Publikationsdatum: 01.07.2009
Verlag: Springer-Verlag
Erschienen in: Intensive Care Medicine / Ausgabe 7/2009
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-009-1424-5

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The impact of obesity on outcomes after critical illness: a meta-analysis

Abstract

Purpose

Methods

Results

Conclusions

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Springer Medizin

Abstract

Purpose

Methods

Results

Conclusions

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