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Erschienen in:
01.02.2011 | Erratum
Erratum to: Design, conduct, analysis and reporting of a multi-national placebo-controlled trial of activated protein C for persistent septic shock
Erschienen in: Intensive Care Medicine | Ausgabe 2/2011
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Due to an oversight by the authors, incorrect data appeared in Table 2. The table is reproduced here with the corrected item in bold type.
Table 2
Serious bleeding rates in clinical trials of drotrecogin alfa (activated)
|
Study
|
Placebo n (%)
|
DAA n (%)
|
P
|
|---|---|---|---|
|
PROWESS
|
17 (2.0)
|
30 (3.5)
|
0.06
|
|
PROWESS (CNS)
|
1 (0.1)
|
2 (0.2)
|
NS
|
|
ADDRESS
|
28 (2.2)
|
51 (3.9)
|
0.01
|
|
ADDRESS (Day 0–6)
|
15 (1.2)
|
31 (2.4)
|
0.02
|
|
ADDRESS (CNS)
|
5 (0.4)
|
6 (0.5)
|
0.72
|
|
RESOLVE
|
16 (6.8)
|
16 (6.7)
|
0.97
|
|
RESOLVE (Day 0–6)
|
8 (3.4)
|
9 (3.8)
|
0.83
|
|
RESOLVE (CNS)
|
5 (2.1)
|
11 (4.6)
|
0.13
|
|
ENHANCE
|
–
|
155 (6.5)
|
–
|